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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
88330

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:88330

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue May 26 09:36:12 2015.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:88330
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0039706co-receptor bindingHFEIPIUniProtKB:Q6ZVN8HumanPMID:22728873
Molecular FunctionGO:0039706co-receptor bindingHFEIPIUniProtKB:Q96B86HumanPMID:22728873
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P61769HumanPMID:10638746
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P02787HumanPMID:15880641
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P02786HumanPMID:15965644
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P61769HumanPMID:15965644
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P02786HumanPMID:20618438
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P61769HumanPMID:20618438
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:O00238HumanPMID:24904118
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P36894HumanPMID:24904118
Molecular FunctionGO:0005515protein bindingHFEIPIUniProtKB:P61769HumanPMID:9465039
Molecular FunctionGO:0005102receptor bindingHFEIPIUniProtKB:P02786HumanPMID:10638746
Molecular FunctionGO:0005102receptor bindingHfeIPIUniProtKB:Q62351|UniProtKB:Q9JKX3MouseMGI:MGI:3695785|PMID:16893896
Molecular FunctionGO:1990459transferrin receptor bindingHFEIPIUniProtKB:Q9UP52HumanPMID:22728873
Molecular FunctionGO:1990459transferrin receptor bindingHFEIPIUniProtKB:P02786HumanPMID:9465039
Cellular ComponentGO:0045177apical part of cellHFEIDAHumanPMID:15880641
Cellular ComponentGO:0045177apical part of cellHfeIDARatRGD:1582698|PMID:16208485
Cellular ComponentGO:0045178basal part of cellHFEIDAHumanPMID:15880641
Cellular ComponentGO:0031410cytoplasmic vesicleHFEIDAHumanPMID:15880641
Cellular ComponentGO:0005769early endosomeHFEIDAHumanPMID:15880641
Cellular ComponentGO:0009897external side of plasma membraneHFEIDAHumanPMID:24904118
Cellular ComponentGO:1990712HFE-transferrin receptor complexHFEIDAHumanPMID:22728873
Cellular ComponentGO:1990712HFE-transferrin receptor complexHFEIDAHumanPMID:9465039
Cellular ComponentGO:1990712HFE-transferrin receptor complexHfeIDAMouseMGI:MGI:3695785|PMID:16893896
Cellular ComponentGO:0031528microvillus membraneHfeIDARatRGD:1582698|PMID:16208485
Cellular ComponentGO:0048471perinuclear region of cytoplasmHFEIDAHumanPMID:15880641
Cellular ComponentGO:0055037recycling endosomeHFEIDAHumanPMID:15880641
Cellular ComponentGO:1990357terminal webHfeIDARatRGD:1582698|PMID:16208485
Biological ProcessGO:0030509BMP signaling pathwayHFEIDAHumanPMID:24904118
Biological ProcessGO:0042446hormone biosynthetic processHfeIMPMGI:MGI:2385353MouseMGI:MGI:3700581|PMID:15914561
Biological ProcessGO:0055072iron ion homeostasisHfeIMPMGI:MGI:1934013MouseMGI:MGI:3043987|PMID:15131800
Biological ProcessGO:0055072iron ion homeostasisHfeIMPMGI:MGI:2385353MouseMGI:MGI:3700581|PMID:15914561
Biological ProcessGO:0055072iron ion homeostasisHfeIMPMouseMGI:MGI:4888467|PMID:21059897
Biological ProcessGO:0055072iron ion homeostasisHfeIMPMGI:MGI:3775648MouseMGI:MGI:5467909|PMID:22960056
Biological ProcessGO:0097459iron ion import into cellHFEIDAHumanPMID:10085150
Biological ProcessGO:0097459iron ion import into cellHfeIMPMGI:MGI:2181388MouseMGI:MGI:1332955|PMID:10077651
Biological ProcessGO:0060586multicellular organismal iron ion homeostasisHfeIMPMGI:MGI:2181388MouseMGI:MGI:1332955|PMID:10077651
Biological ProcessGO:2000059negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processHFEIDAHumanPMID:24904118
Biological ProcessGO:1900121negative regulation of receptor bindingHFEIDAHumanPMID:9465039
Biological ProcessGO:0010628positive regulation of gene expressionHfeIMPMouseMGI:MGI:5603002|PMID:24904118
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationHFEIDAHumanPMID:24904118

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory