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Comparative GO Graph (human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
8509

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:8509

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:8509
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0043125ErbB-3 class receptor bindingNRG1IPIUniProtKB:P21860HumanPMID:11389077
Molecular FunctionGO:0043125ErbB-3 class receptor bindingNRG1IDAHumanPMID:7556068
Molecular FunctionGO:0043125ErbB-3 class receptor bindingNrg1IMPRatRGD:1581607|PMID:11082038
Molecular FunctionGO:0008083growth factor activityNRG1IDAHumanPMID:11389077
Molecular FunctionGO:0005515protein bindingNRG1IPIUniProtKB:P04626HumanPMID:7592681
Molecular FunctionGO:0005515protein bindingNRG1IPIUniProtKB:P21860HumanPMID:7592681
Molecular FunctionGO:0030296protein tyrosine kinase activator activityNRG1IDAHumanPMID:7556068
Molecular FunctionGO:0005102receptor bindingNRG1IPIUniProtKB:A6QR62HumanPMID:7514177
Molecular FunctionGO:0003712transcription cofactor activityNRG1IDAHumanPMID:15073182
Cellular ComponentGO:0016324apical plasma membraneNRG1IDAHumanPMID:12646923
Cellular ComponentGO:0005615extracellular spaceNRG1IDAHumanPMID:11389077
Cellular ComponentGO:0005615extracellular spaceNRG1IDAHumanPMID:12646923
Biological ProcessGO:0007171activation of transmembrane receptor protein tyrosine kinase activityNRG1IDAHumanPMID:9553078
Biological ProcessGO:0060379cardiac muscle cell myoblast differentiationNRG1IDAHumanPMID:17336907
Biological ProcessGO:0008283cell proliferationNRG1IDAHumanPMID:11389077
Biological ProcessGO:0043624cellular protein complex disassemblyNRG1IGIUniProtKB:P25304HumanPMID:15155732
Biological ProcessGO:0060956endocardial cell differentiationNRG1IDAHumanPMID:17336907
Biological ProcessGO:0038127ERBB signaling pathwayNRG1IDAHumanPMID:11389077
Biological ProcessGO:0015758glucose transportNrg1IMPRatRGD:1581607|PMID:11082038
Biological ProcessGO:0010667negative regulation of cardiac muscle cell apoptotic processNRG1IDAHumanPMID:9553078
Biological ProcessGO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandNRG1IDAHumanPMID:9553078
Biological ProcessGO:0051048negative regulation of secretionNRG1IDAHumanPMID:10559227
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedNRG1IDAHumanPMID:15073182
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationNRG1IDAHumanPMID:9553078
Biological ProcessGO:0045785positive regulation of cell adhesionNRG1IDAHumanPMID:7556068
Biological ProcessGO:0030307positive regulation of cell growthNRG1IDAHumanPMID:9553078
Biological ProcessGO:0061098positive regulation of protein tyrosine kinase activityNRG1IDAHumanPMID:7556068
Biological ProcessGO:0043497regulation of protein heterodimerization activityNRG1IDAHumanPMID:10559227
Biological ProcessGO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayNRG1IDAHumanPMID:7514177
Biological ProcessGO:0055012ventricular cardiac muscle cell differentiationNRG1IDAHumanPMID:9553078
Biological ProcessGO:0003222ventricular trabecula myocardium morphogenesisNRG1IDAHumanPMID:17336907
Biological ProcessGO:0042060wound healingNRG1IDAHumanPMID:12646923

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory