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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
828

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:828

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:828
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0002020protease bindingTnfrsf1aIPIRGD:620945RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0002020protease bindingTnfrsf1aIPIRGD:708542RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P42224HumanPMID:10848577
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P51397HumanPMID:1087798
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:11684708
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:12887920
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:14743216
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q9NXR7HumanPMID:15465831
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q12933HumanPMID:16611992
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q13546HumanPMID:16611992
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:16611992
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q13546HumanPMID:18022363
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q13546HumanPMID:19524513
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:19524513
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q13546HumanPMID:19781631
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:19781631
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:20103630
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:22028622
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q13546HumanPMID:22817896
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:24070898
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P28799HumanPMID:24070898
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q9D1X0HumanPMID:24440909
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q12933HumanPMID:25241761
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:25911380
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:P01375HumanPMID:2848815
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:7758105
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:8565075
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q12933HumanPMID:8943045
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q15628HumanPMID:8943045
Molecular FunctionGO:0005515protein bindingTNFRSF1AIPIUniProtKB:Q8WXG6HumanPMID:9115275
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q05910MouseMGI:MGI:4831059|PMID:20826683
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q8K3K8MouseMGI:MGI:3766891|PMID:17702576
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:O88522MouseMGI:MGI:3766891|PMID:17702576
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q31125MouseMGI:MGI:3688344|PMID:15102471
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q60855MouseMGI:MGI:3766891|PMID:17702576
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q60855MouseMGI:MGI:3687669|PMID:10463949
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q60855|UniProtKB:Q9EQY0MouseMGI:MGI:5508636|PMID:16680093
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q8CFV9MouseMGI:MGI:4355761|PMID:19641494
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:Q60855MouseMGI:MGI:5512838|PMID:18022363
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIUniProtKB:P27958:PRO_0000037566|UniProtKB:P39429|UniProtKB:Q15628MouseMGI:MGI:5616328|PMID:11374864
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIRGD:1310457RatRGD:5130945|PMID:20967881
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIRGD:620888RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIRGD:621313RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0005515protein bindingTnfrsf1aIPIRGD:628700RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0032403protein complex bindingTnfrsf1aIPIRGD:621313|RGD:1310457RatRGD:1624191|PMID:15590916
Molecular FunctionGO:0043120tumor necrosis factor bindingTnfrsf1aIPIRGD:3876RatRGD:5130976|PMID:20649583
Molecular FunctionGO:0005031tumor necrosis factor-activated receptor activityTnfrsf1aIPIUniProtKB:P06804|UniProtKB:P01374MouseMGI:MGI:59648|PMID:1645445
Molecular FunctionGO:0005031tumor necrosis factor-activated receptor activityTnfrsf1aIMPMGI:MGI:1861040MouseMGI:MGI:2152007|PMID:11588035
Molecular FunctionGO:0005031tumor necrosis factor-activated receptor activityTnfrsf1aIMPRatRGD:5130976|PMID:20649583
Cellular ComponentGO:0030424axonTnfrsf1aIDARatRGD:5130963|PMID:11240015
Cellular ComponentGO:0009986cell surfaceTnfrsf1aIDAMouseMGI:MGI:5306543|PMID:21410936
Cellular ComponentGO:0009986cell surfaceTnfrsf1aIDARatRGD:5130976|PMID:20649583
Cellular ComponentGO:0005829cytosolTnfrsf1aIDARatRGD:8661758|PMID:21741934
Cellular ComponentGO:0005615extracellular spaceTNFRSF1AIDAHumanPMID:13130484
Cellular ComponentGO:0005615extracellular spaceTnfrsf1aIDARatRGD:5130976|PMID:20649583
Cellular ComponentGO:0000139Golgi membraneTNFRSF1AIDAHumanPMID:22801493
Cellular ComponentGO:0045121membrane raftTNFRSF1AIDAHumanPMID:17010968
Cellular ComponentGO:0045121membrane raftTnfrsf1aIDAMouseMGI:MGI:3828392|PMID:17010968
Cellular ComponentGO:0045121membrane raftTnfrsf1aIDARatRGD:1624191|PMID:15590916
Cellular ComponentGO:0005739mitochondrionTnfrsf1aIDARatRGD:8661758|PMID:21741934
Cellular ComponentGO:0005634nucleusTnfrsf1aIDARatRGD:5130963|PMID:11240015
Cellular ComponentGO:0043234protein complexTnfrsf1aIDARatRGD:1624191|PMID:15590916
Cellular ComponentGO:0043234protein complexTnfrsf1aIMPRatRGD:5130945|PMID:20967881
Cellular ComponentGO:0043235receptor complexTNFRSF1AIDAHumanPMID:23382219
Cellular ComponentGO:0045202synapseTnfrsf1aIDARatRGD:8661759|PMID:22522145
Biological ProcessGO:0007166cell surface receptor signaling pathwayTnfrsf1aIMPMGI:MGI:1857468MouseMGI:MGI:1194456|PMID:9551933
Biological ProcessGO:0019221cytokine-mediated signaling pathwayTnfrsf1aIMPMGI:MGI:1861040MouseMGI:MGI:2152007|PMID:11588035
Biological ProcessGO:0006952defense responseTnfrsf1aIMPMGI:MGI:1857261MouseMGI:MGI:53235|PMID:8387893
Biological ProcessGO:0042742defense response to bacteriumTnfrsf1aIMPMGI:MGI:1857261MouseMGI:MGI:1097215|PMID:9324362
Biological ProcessGO:0090002establishment of protein localization to plasma membraneTNFRSF1AIMPHumanPMID:25816133
Biological ProcessGO:0006954inflammatory responseTnfrsf1aIMPMGI:MGI:1857468MouseMGI:MGI:1328447|PMID:9843922
Biological ProcessGO:0006954inflammatory responseTnfrsf1aIMPMGI:MGI:1857468MouseMGI:MGI:1194456|PMID:9551933
Biological ProcessGO:0008630intrinsic apoptotic signaling pathway in response to DNA damageTnfrsf1aIMPMouseMGI:MGI:3709926|PMID:17242187
Biological ProcessGO:0043066negative regulation of apoptotic processTnfrsf1aIMPRatRGD:7245942|PMID:23028454
Biological ProcessGO:0010629negative regulation of gene expressionTnfrsf1aIDARatRGD:5130988|PMID:20501675
Biological ProcessGO:0050728negative regulation of inflammatory responseTNFRSF1AIMPHumanPMID:13130484
Biological ProcessGO:0032715negative regulation of interleukin-6 productionTnfrsf1aIDARatRGD:5130988|PMID:20501675
Biological ProcessGO:0045766positive regulation of angiogenesisTnfrsf1aIMPRatRGD:1624195|PMID:14970118
Biological ProcessGO:0010628positive regulation of gene expressionTnfrsf1aIMPRatRGD:5130967|PMID:20700128
Biological ProcessGO:0050729positive regulation of inflammatory responseTnfrsf1aIMPMGI:MGI:1857261,MGI:MGI:2652655MouseMGI:MGI:5565533|PMID:24211183
Biological ProcessGO:0050729positive regulation of inflammatory responseTnfrsf1aIMPMGI:MGI:1861040MouseMGI:MGI:2152007|PMID:11588035
Biological ProcessGO:0043525positive regulation of neuron apoptotic processTnfrsf1aIMPRatRGD:8661759|PMID:22522145
Biological ProcessGO:0033160positive regulation of protein import into nucleus, translocationTnfrsf1aIMPRatRGD:5130945|PMID:20967881
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTNFRSF1AIMPHumanPMID:21410936
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTnfrsf1aIMPMGI:MGI:1861040MouseMGI:MGI:2152007|PMID:11588035
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionTnfrsf1aIMPRatRGD:5130945|PMID:20967881
Biological ProcessGO:0051291protein heterooligomerizationTnfrsf1aIPIRGD:621313|RGD:1560875RatRGD:2298728|PMID:12786973
Biological ProcessGO:0042981regulation of apoptotic processTnfrsf1aIMPRatRGD:5130945|PMID:20967881
Biological ProcessGO:1903140regulation of establishment of endothelial barrierTNFRSF1AIMPHumanPMID:25816133
Biological ProcessGO:0033209tumor necrosis factor-mediated signaling pathwayTNFRSF1AIMPHumanPMID:25816133
Biological ProcessGO:0033209tumor necrosis factor-mediated signaling pathwayTnfrsf1aIMPRatRGD:5130945|PMID:20967881

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory