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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
81697

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:81697

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:81697
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003677DNA bindingNpm1IDARatRGD:1600911|PMID:8611572
Molecular FunctionGO:0019899enzyme bindingNpm1IPIRGD:620335RatRGD:1600871|PMID:15893727
Molecular FunctionGO:0019899enzyme bindingNpm1IDARatRGD:1600909|PMID:11481036
Molecular FunctionGO:0042393histone bindingNPM1IDAHumanPMID:11602260
Molecular FunctionGO:0051059NF-kappaB bindingNPM1IDAHumanPMID:15087454
Molecular FunctionGO:0005547phosphatidylinositol-3,4,5-trisphosphate bindingNpm1IPICHEBI:16618RatRGD:1600871|PMID:15893727
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P04637HumanPMID:12080348
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P46087HumanPMID:12080348
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P19525HumanPMID:12882984
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P04637HumanPMID:15144954
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q00987HumanPMID:15144954
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q98147HumanPMID:15144954
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P63104HumanPMID:15161933
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q99728HumanPMID:15184379
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q8N726HumanPMID:15989956
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P04637HumanPMID:16376884
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P19338HumanPMID:16648475
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P37198HumanPMID:16648475
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P46777HumanPMID:16648475
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9UKX7HumanPMID:16648475
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P19525HumanPMID:16957780
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q8N726HumanPMID:16957780
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:O75116HumanPMID:17015463
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P05549HumanPMID:17318229
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q13547HumanPMID:17318229
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q92769HumanPMID:17318229
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P61201HumanPMID:17438371
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9Y3A5HumanPMID:17475909
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P24938HumanPMID:17602943
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P68951HumanPMID:17602943
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9H4L4HumanPMID:18259216
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P46781HumanPMID:18420587
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P27695HumanPMID:19188445
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P49450HumanPMID:19410545
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P46783HumanPMID:20159986
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:P63104HumanPMID:20618440
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q8IZL8HumanPMID:21326211
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9H4L4HumanPMID:21326211
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q10570HumanPMID:21822216
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q00987HumanPMID:22510990
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9BZQ8HumanPMID:22510990
Molecular FunctionGO:0005515protein bindingNPM1IPIUniProtKB:Q9BXL5HumanPMID:22712502
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:O88443MouseMGI:MGI:1270060|PMID:9642267
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:Q64364MouseMGI:MGI:3511413|PMID:15485902
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:P62843|UniProtKB:Q6ZWU9|UniProtKB:P62960|UniProtKB:Q61858|UniProtKB:Q9CPP0MouseMGI:MGI:3573985|PMID:15596447
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:P47962MouseMGI:MGI:3625664|PMID:16648475
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:P20152MouseMGI:MGI:3697024|PMID:17015463
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:P70336MouseMGI:MGI:3697024|PMID:17015463
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:Q91YK2MouseMGI:MGI:4436996|PMID:19710015
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:Q00987MouseMGI:MGI:4456951|PMID:15144954
Molecular FunctionGO:0005515protein bindingNpm1IPIUniProtKB:Q03963MouseMGI:MGI:5486564|PMID:12882984
Molecular FunctionGO:0046982protein heterodimerization activityNPM1IMPHumanPMID:12080348
Molecular FunctionGO:0042803protein homodimerization activityNPM1IDAHumanPMID:9121481
Molecular FunctionGO:0019901protein kinase bindingNPM1IPIUniProtKB:Q9NYY3HumanPMID:20352051
Molecular FunctionGO:0004860protein kinase inhibitor activityNPM1IDAHumanPMID:12882984
Molecular FunctionGO:0043023ribosomal large subunit bindingNPM1IDAHumanPMID:18809582
Molecular FunctionGO:0043024ribosomal small subunit bindingNPM1IDAHumanPMID:18809582
Molecular FunctionGO:0003723RNA bindingNPM1IDAHumanPMID:12058066
Molecular FunctionGO:0003723RNA bindingNpm1IDAMouseMGI:MGI:3615094|PMID:16376875
Molecular FunctionGO:0019843rRNA bindingNpm1IDAMouseMGI:MGI:3573985|PMID:15596447
Molecular FunctionGO:0019843rRNA bindingNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Molecular FunctionGO:0030957Tat protein bindingNPM1IDAHumanPMID:9094689
Molecular FunctionGO:0003713transcription coactivator activityNPM1IDAHumanPMID:15087454
Molecular FunctionGO:0051082unfolded protein bindingNPM1IDAHumanPMID:10211837
Cellular ComponentGO:0005623cellNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0005813centrosomeNPM1IDAHumanPMID:11051553
Cellular ComponentGO:0005813centrosomeNpm1IDAMouseMGI:MGI:3610707|PMID:16297385
Cellular ComponentGO:0005737cytoplasmNPM1IDAHumanPMID:9121481
Cellular ComponentGO:0005737cytoplasmNpm1IDAMouseMGI:MGI:3625664|PMID:16648475
Cellular ComponentGO:0005829cytosolNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0001652granular componentNpm1IDAMouseMGI:MGI:3511413|PMID:15485902
Cellular ComponentGO:0005622intracellularNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0015934large ribosomal subunitNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0016607nuclear speckNpm1IDAMouseMGI:MGI:3615094|PMID:16376875
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:11420665
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:12080348
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:16041368
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:17475909
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:18809582
Cellular ComponentGO:0005730nucleolusNPM1IDAHumanPMID:19188445
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:80200|PMID:2100262
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:1891512|PMID:10716735
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:2446969|PMID:12374805
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3511413|PMID:15485902
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3522381|PMID:15615785
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3573985|PMID:15596447
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3583493|PMID:15989966
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3608543|PMID:16027046
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3610707|PMID:16297385
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3625664|PMID:16648475
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3689171|PMID:16855206
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3771267|PMID:18023416
Cellular ComponentGO:0005730nucleolusNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0005730nucleolusNpm1IDARatRGD:1566578|PMID:12450141
Cellular ComponentGO:0005654nucleoplasmNPM1IDAHumanPMID:12058066
Cellular ComponentGO:0005654nucleoplasmNpm1IDAMouseMGI:MGI:2446969|PMID:12374805
Cellular ComponentGO:0005654nucleoplasmNpm1IDAMouseMGI:MGI:3610707|PMID:16297385
Cellular ComponentGO:0005654nucleoplasmNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0005634nucleusNPM1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusNPM1IDAHumanPMID:12080348
Cellular ComponentGO:0005634nucleusNpm1IDAMouseMGI:MGI:3625664|PMID:16648475
Cellular ComponentGO:0030529ribonucleoprotein complexNPM1IDAHumanPMID:18809582
Cellular ComponentGO:0015935small ribosomal subunitNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Cellular ComponentGO:0031616spindle pole centrosomeNPM1IDAHumanPMID:16041368
Biological ProcessGO:0007569cell agingNPM1IMPHumanPMID:12080348
Biological ProcessGO:0016049cell growthNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0006884cell volume homeostasisNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0006884cell volume homeostasisNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0007098centrosome cycleNPM1IMPHumanPMID:11051553
Biological ProcessGO:0006281DNA repairNPM1IDAHumanPMID:19188445
Biological ProcessGO:0043066negative regulation of apoptotic processNPM1IDAHumanPMID:12882984
Biological ProcessGO:0008285negative regulation of cell proliferationNPM1IMPHumanPMID:12080348
Biological ProcessGO:0010826negative regulation of centrosome duplicationNPM1IMPHumanPMID:16041368
Biological ProcessGO:0048025negative regulation of mRNA splicing, via spliceosomeNpm1IDAMouseMGI:MGI:3615094|PMID:16376875
Biological ProcessGO:0044387negative regulation of protein kinase activity by regulation of protein phosphorylationNPM1IDAHumanPMID:12882984
Biological ProcessGO:0006913nucleocytoplasmic transportNPM1IDAHumanPMID:16041368
Biological ProcessGO:0006913nucleocytoplasmic transportNpm1IDAMouseMGI:MGI:3511413|PMID:15485902
Biological ProcessGO:0006334nucleosome assemblyNPM1IDAHumanPMID:11602260
Biological ProcessGO:0043085positive regulation of catalytic activityNpm1IDARatRGD:1600909|PMID:11481036
Biological ProcessGO:0008284positive regulation of cell proliferationNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0008284positive regulation of cell proliferationNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0031328positive regulation of cellular biosynthetic processNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0031328positive regulation of cellular biosynthetic processNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0010825positive regulation of centrosome duplicationNpm1IGIUniProtKB:Q28201MouseMGI:MGI:3697024|PMID:17015463
Biological ProcessGO:0051054positive regulation of DNA metabolic processNpm1IDARatRGD:1600909|PMID:11481036
Biological ProcessGO:0045740positive regulation of DNA replicationNpm1IDARatRGD:1600909|PMID:11481036
Biological ProcessGO:0051092positive regulation of NF-kappaB transcription factor activityNPM1IMPHumanPMID:15087454
Biological ProcessGO:0045860positive regulation of protein kinase activityNpm1IDAMouseMGI:MGI:3697024|PMID:17015463
Biological ProcessGO:0045727positive regulation of translationNPM1IDAHumanPMID:12882984
Biological ProcessGO:0031648protein destabilizationNpm1IMPMouseMGI:MGI:62033
Biological ProcessGO:0051260protein homooligomerizationNpm1IDARatRGD:1600911|PMID:8611572
Biological ProcessGO:0008104protein localizationNPM1IDAHumanPMID:18420587
Biological ProcessGO:0008104protein localizationNpm1IMPMGI:MGI:3604210MouseMGI:MGI:3603875|PMID:16199867
Biological ProcessGO:0051259protein oligomerizationNPM1IDAHumanPMID:18809582
Biological ProcessGO:0051726regulation of cell cycleNpm1IMPMouseMGI:MGI:3511413|PMID:15485902
Biological ProcessGO:0046599regulation of centriole replicationNPM1IMPHumanPMID:20352051
Biological ProcessGO:0010824regulation of centrosome duplicationNpm1IMPMGI:MGI:3604807MouseMGI:MGI:3604166|PMID:16007073
Biological ProcessGO:0043516regulation of DNA damage response, signal transduction by p53 class mediatorNpm1IGIMGI:MGI:98834MouseMGI:MGI:3603875|PMID:16199867
Biological ProcessGO:0060735regulation of eIF2 alpha phosphorylation by dsRNANPM1IDAHumanPMID:12882984
Biological ProcessGO:0032071regulation of endodeoxyribonuclease activityNPM1IDAHumanPMID:19188445
Biological ProcessGO:0060699regulation of endoribonuclease activityNPM1IDAHumanPMID:19188445
Biological ProcessGO:0043523regulation of neuron apoptotic processNpm1IMPRatRGD:1600871|PMID:15893727
Biological ProcessGO:0006950response to stressNPM1IMPHumanPMID:12080348
Biological ProcessGO:0042273ribosomal large subunit biogenesisNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0042273ribosomal large subunit biogenesisNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0000055ribosomal large subunit export from nucleusNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0042274ribosomal small subunit biogenesisNpm1IMPMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0042274ribosomal small subunit biogenesisNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0000056ribosomal small subunit export from nucleusNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0006407rRNA export from nucleusNpm1IDAMouseMGI:MGI:3822232|PMID:18809582
Biological ProcessGO:0006407rRNA export from nucleusNpm1IMPMouseMGI:MGI:3822232|PMID:18809582

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory