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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
80210

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:80210

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:80210
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:007188914-3-3 protein bindingRPTORIDAHumanPMID:18439900
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:12150925
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P23443HumanPMID:12150926
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:12150926
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P67999HumanPMID:12150926
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q13541HumanPMID:12150926
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9JLN9HumanPMID:12150926
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:12408816
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9BVC4HumanPMID:12408816
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q96B36HumanPMID:17386266
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:17461779
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:17565979
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q8TCU6HumanPMID:17565979
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q13541HumanPMID:18337751
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:19446321
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:19619545
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:19875983
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P70445HumanPMID:20347422
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9BVC4HumanPMID:20562859
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:21045808
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q8TCU6HumanPMID:21339740
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q96EB6HumanPMID:21471201
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:22424946
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9P2J5HumanPMID:22424946
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P50406HumanPMID:23027611
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:23953116
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q13283HumanPMID:23953116
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q96R06HumanPMID:23953116
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:24036451
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345,UniProtKB:Q9NWS0,UniProtKB:Q9Y4R8HumanPMID:24036451
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9BVC4HumanPMID:24036451
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9JLN9HumanPMID:24036451
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:24375676
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P42345HumanPMID:25446900
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:P62820HumanPMID:25446900
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9HB90HumanPMID:25446900
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q9HB90HumanPMID:25561175
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q6PJG6HumanPMID:25657994
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q6PKG0HumanPMID:25940091
Molecular FunctionGO:0005515protein bindingRPTORIPIUniProtKB:Q13615HumanPMID:26787466
Molecular FunctionGO:0005515protein bindingRptorIPIUniProtKB:Q9JLN9MouseMGI:MGI:4830417|PMID:20801936
Molecular FunctionGO:0005515protein bindingRptorIPIUniProtKB:Q9JLN9MouseMGI:MGI:4867369|PMID:21045808
Molecular FunctionGO:0030674protein binding, bridgingRPTORIDAHumanPMID:12150926
Molecular FunctionGO:0032403protein complex bindingRPTORIPIUniProtKB:O75385HumanPMID:19211835
Molecular FunctionGO:0030295protein kinase activator activityRPTORIDAHumanPMID:12150926
Molecular FunctionGO:0019901protein kinase bindingRPTORIPIUniProtKB:P54646HumanPMID:18439900
Molecular FunctionGO:0019901protein kinase bindingRPTORIPIUniProtKB:Q13131HumanPMID:18439900
Molecular FunctionGO:0019901protein kinase bindingRptorIPIRGD:68371RatRGD:2307416|PMID:15525761
Molecular FunctionGO:0030291protein serine/threonine kinase inhibitor activityRPTORIDAHumanPMID:12718876
Molecular FunctionGO:0001030RNA polymerase III type 1 promoter DNA bindingRPTORIDAHumanPMID:20233713
Molecular FunctionGO:0001031RNA polymerase III type 2 promoter DNA bindingRPTORIDAHumanPMID:20233713
Molecular FunctionGO:0001032RNA polymerase III type 3 promoter DNA bindingRPTORIDAHumanPMID:20233713
Molecular FunctionGO:0001156TFIIIC-class transcription factor bindingRPTORIDAHumanPMID:20543138
Cellular ComponentGO:0005737cytoplasmRPTORIDAHumanPMID:20381137
Cellular ComponentGO:0010494cytoplasmic stress granuleRPTORIDAHumanPMID:25940091
Cellular ComponentGO:0005829cytosolRPTORIDAHumanGO_REF:0000052
Cellular ComponentGO:0030425dendriteRptorIDARatRGD:2307416|PMID:15525761
Cellular ComponentGO:0005765lysosomal membraneRPTORIDAHumanPMID:17897319
Cellular ComponentGO:0005764lysosomeRPTORIDAHumanGO_REF:0000052
Cellular ComponentGO:0005764lysosomeRPTORIDAHumanPMID:20381137
Cellular ComponentGO:0005764lysosomeRPTORIMPHumanPMID:22424946
Cellular ComponentGO:0043025neuronal cell bodyRptorIDARatRGD:2307416|PMID:15525761
Cellular ComponentGO:0005654nucleoplasmRPTORIDAHumanGO_REF:0000052
Cellular ComponentGO:0031931TORC1 complexRPTORIDAHumanPMID:12150926
Cellular ComponentGO:0031931TORC1 complexRPTORIDAHumanPMID:12718876
Cellular ComponentGO:0031931TORC1 complexRPTORIDAHumanPMID:15467718
Cellular ComponentGO:0031931TORC1 complexRPTORIDAHumanPMID:24036451
Cellular ComponentGO:0031931TORC1 complexRPTORIDAHumanPMID:25940091
Biological ProcessGO:0016049cell growthRPTORIMPHumanPMID:20381137
Biological ProcessGO:0071230cellular response to amino acid stimulusRPTORIMPHumanPMID:20381137
Biological ProcessGO:0071233cellular response to leucineRPTORIDAHumanPMID:22424946
Biological ProcessGO:0031669cellular response to nutrient levelsRPTORIMPHumanPMID:12150925
Biological ProcessGO:0046676negative regulation of insulin secretionRptorIMPMouseMGI:MGI:5619445|PMID:23092880
Biological ProcessGO:0030307positive regulation of cell growthRPTORIMPHumanPMID:18426977
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationRptorIMPRatRGD:2307383|PMID:17110594
Biological ProcessGO:1900087positive regulation of G1/S transition of mitotic cell cycleRPTORIMPHumanPMID:18426977
Biological ProcessGO:0033138positive regulation of peptidyl-serine phosphorylationRPTORIMPHumanPMID:18426977
Biological ProcessGO:0010800positive regulation of peptidyl-threonine phosphorylationRPTORIMPHumanPMID:18426977
Biological ProcessGO:0071902positive regulation of protein serine/threonine kinase activityRPTORIDAHumanPMID:12150926
Biological ProcessGO:0032008positive regulation of TOR signalingRPTORIDAHumanPMID:12150926
Biological ProcessGO:0032008positive regulation of TOR signalingRPTORIDAHumanPMID:18439900
Biological ProcessGO:0045945positive regulation of transcription from RNA polymerase III promoterRPTORIMPHumanPMID:20233713
Biological ProcessGO:0008361regulation of cell sizeRPTORIMPHumanPMID:12150925
Biological ProcessGO:0042325regulation of phosphorylationRptorIMPRatRGD:2307383|PMID:17110594
Biological ProcessGO:0001932regulation of protein phosphorylationRptorIMPMouseMGI:MGI:5619445|PMID:23092880
Biological ProcessGO:0031929TOR signalingRPTORIDAHumanPMID:20381137
Biological ProcessGO:0038202TORC1 signalingRPTORIMPHumanPMID:12718876

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/15/2017
MGI 6.10
The Jackson Laboratory