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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7865

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:7865

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:7865
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0019899enzyme bindingNotch2IPIUniProtKB:Q9NWT6MouseMGI:MGI:5318027|PMID:17573339
Molecular FunctionGO:0051059NF-kappaB bindingNotch2IPIUniProtKB:Q04207MouseMGI:MGI:3814108|PMID:18710934
Molecular FunctionGO:0005515protein bindingNOTCH2IPIUniProtKB:O00548HumanPMID:10079256
Molecular FunctionGO:0005515protein bindingNOTCH2IPIUniProtKB:Q92585HumanPMID:11101851
Molecular FunctionGO:0005515protein bindingNOTCH2IPIUniProtKB:O00548HumanPMID:11823422
Molecular FunctionGO:0005515protein bindingNotch2IPIUniProtKB:P31266MouseMGI:MGI:87634|PMID:9111338
Molecular FunctionGO:0005515protein bindingNotch2IPIUniProtKB:Q9QXX0MouseMGI:MGI:1347427|PMID:10551863
Molecular FunctionGO:0005515protein bindingNotch2IPIUniProtKB:Q61483|UniProtKB:Q9QYE5MouseMGI:MGI:3691907|PMID:12496659
Cellular ComponentGO:0005623cellNotch2IGIMGI:MGI:97363MouseMGI:MGI:3718932|PMID:17658279
Cellular ComponentGO:0009986cell surfaceNOTCH2IDAHumanPMID:9244302
Cellular ComponentGO:0005929ciliumNotch2IDAMouseMGI:MGI:5013962|PMID:21703454
Cellular ComponentGO:0005887integral component of plasma membraneNOTCH2IDAHumanPMID:9244302
Cellular ComponentGO:0016020membraneNOTCH2IDAHumanPMID:19946888
Cellular ComponentGO:0005634nucleusNOTCH2IDAHumanPMID:1303260
Cellular ComponentGO:0005634nucleusNotch2IDAMouseMGI:MGI:3691907|PMID:12496659
Cellular ComponentGO:0043235receptor complexNOTCH2IDAHumanPMID:23382219
Biological ProcessGO:0060413atrial septum morphogenesisNOTCH2IMPHumanPMID:16773578
Biological ProcessGO:0046849bone remodelingNOTCH2IMPHumanPMID:21378985
Biological ProcessGO:0046849bone remodelingNOTCH2IMPHumanPMID:21378989
Biological ProcessGO:0007050cell cycle arrestNOTCH2IDAHumanPMID:11306509
Biological ProcessGO:0001709cell fate determinationNotch2IDARatRGD:69906|PMID:1295745
Biological ProcessGO:0016049cell growthNOTCH2IDAHumanPMID:11306509
Biological ProcessGO:0061073ciliary body morphogenesisNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5492288|PMID:23676271
Biological ProcessGO:0042742defense response to bacteriumNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5562510|PMID:23913046
Biological ProcessGO:0007368determination of left/right symmetryNotch2IMPMGI:MGI:1933205MouseMGI:MGI:2661305|PMID:12730124
Biological ProcessGO:0030326embryonic limb morphogenesisNotch2IGIMGI:MGI:97363MouseMGI:MGI:3610505|PMID:16169548
Biological ProcessGO:0001947heart loopingNotch2IGIUniProtKB:Q01705MouseMGI:MGI:2661305|PMID:12730124
Biological ProcessGO:0006959humoral immune responseNotch2IGIMGI:MGI:97363MouseMGI:MGI:3718932|PMID:17658279
Biological ProcessGO:0001701in utero embryonic developmentNotch2IMPMGI:MGI:1857783MouseMGI:MGI:3703838|PMID:17359302
Biological ProcessGO:0002437inflammatory response to antigenic stimulusNotch2IGIMGI:MGI:97363MouseMGI:MGI:3718932|PMID:17658279
Biological ProcessGO:0072602interleukin-4 secretionNotch2IGIMGI:MGI:97363MouseMGI:MGI:3718932|PMID:17658279
Biological ProcessGO:0070986left/right axis specificationNotch2IGIUniProtKB:Q01705MouseMGI:MGI:2661305|PMID:12730124
Biological ProcessGO:0002011morphogenesis of an epithelial sheetNotch2IMPMGI:MGI:1933205MouseMGI:MGI:2158685|PMID:11861489
Biological ProcessGO:0043011myeloid dendritic cell differentiationNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5562510|PMID:23913046
Biological ProcessGO:0008285negative regulation of cell proliferationNOTCH2IDAHumanPMID:11306509
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5492288|PMID:23676271
Biological ProcessGO:0060674placenta blood vessel developmentNotch2IMPMGI:MGI:1857783MouseMGI:MGI:3703838|PMID:17359302
Biological ProcessGO:0001890placenta developmentNotch2IMPMGI:MGI:1857783MouseMGI:MGI:3703838|PMID:17359302
Biological ProcessGO:0043065positive regulation of apoptotic processNotch2IGIMGI:MGI:97363MouseMGI:MGI:3610505|PMID:16169548
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5492288|PMID:23676271
Biological ProcessGO:0008284positive regulation of cell proliferationNotch2IMPMGI:MGI:3617328MouseMGI:MGI:5492288|PMID:23676271
Biological ProcessGO:0045672positive regulation of osteoclast differentiationNotch2IDAMouseMGI:MGI:3814108|PMID:18710934
Biological ProcessGO:0046579positive regulation of Ras protein signal transductionNOTCH2IDAHumanPMID:11306509
Biological ProcessGO:0003184pulmonary valve morphogenesisNOTCH2IMPHumanPMID:16773578
Biological ProcessGO:0042060wound healingNotch2IDAMouseMGI:MGI:3691907|PMID:12496659

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory