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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7485

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:7485

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:7485
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingPpargc1aIDARatRGD:7242168|PMID:22705949
Molecular FunctionGO:0031490chromatin DNA bindingPpargc1aIDAMouseMGI:MGI:3771455|PMID:17952069
Molecular FunctionGO:0003677DNA bindingPpargc1aIDAMouseMGI:MGI:3529655|PMID:15681609
Molecular FunctionGO:0016922ligand-dependent nuclear receptor bindingPPARGC1AIPIUniProtKB:P24468HumanPMID:18798693
Molecular FunctionGO:0030374ligand-dependent nuclear receptor transcription coactivator activityPPARGC1AIDAHumanPMID:16488887
Molecular FunctionGO:0005515protein bindingPPARGC1AIPIUniProtKB:P42704HumanPMID:17050673
Molecular FunctionGO:0005515protein bindingPPARGC1AIPIUniProtKB:P62508HumanPMID:19171140
Molecular FunctionGO:0005515protein bindingPPARGC1AIPIUniProtKB:P62508HumanPMID:19914244
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:P53995MouseMGI:MGI:3032469|PMID:14744933
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q8R349MouseMGI:MGI:3032469|PMID:14744933
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q7TPV4MouseMGI:MGI:3032469|PMID:14744933
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q923E4MouseMGI:MGI:3531058|PMID:15744310
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q923E4MouseMGI:MGI:3579714|PMID:15716268
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q6PB66MouseMGI:MGI:3689757|PMID:17050673
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:P51448|UniProtKB:P51450MouseMGI:MGI:3715412|PMID:17476214
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:Q91ZP3-1MouseMGI:MGI:3770090|PMID:16950137
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:P51949MouseMGI:MGI:3770112|PMID:17276355
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:A2A935MouseMGI:MGI:3770355|PMID:17618855
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:A2A935MouseMGI:MGI:4365360|PMID:18483224
Molecular FunctionGO:0005515protein bindingPpargc1aIPIUniProtKB:P23204MouseMGI:MGI:4819323|PMID:20385772
Molecular FunctionGO:0043565sequence-specific DNA bindingPPARGC1AIDAHumanPMID:23836911
Molecular FunctionGO:0003713transcription coactivator activityPPARGC1AIDAHumanPMID:19651776
Molecular FunctionGO:0003713transcription coactivator activityPPARGC1AIDAHumanPMID:21376232
Molecular FunctionGO:0003713transcription coactivator activityPpargc1aIMPMouseMGI:MGI:3689805|PMID:16271724
Molecular FunctionGO:0003713transcription coactivator activityPpargc1aIDAMouseMGI:MGI:3715412|PMID:17476214
Molecular FunctionGO:0003713transcription coactivator activityPpargc1aIDARatRGD:633650|PMID:12107181
Molecular FunctionGO:0008134transcription factor bindingPpargc1aIPIUniProtKB:P26687MouseMGI:MGI:3843109|PMID:19345188
Cellular ComponentGO:0005829cytosolPpargc1aIDARatRGD:1601465|PMID:17099248
Cellular ComponentGO:0005634nucleusPPARGC1AIDAHumanPMID:23836911
Cellular ComponentGO:0005634nucleusPpargc1aIDAMouseMGI:MGI:3771455|PMID:17952069
Cellular ComponentGO:0005634nucleusPpargc1aIDARatRGD:1601465|PMID:17099248
Biological ProcessGO:0034599cellular response to oxidative stressPpargc1aIMPMouseMGI:MGI:4462723|PMID:20566846
Biological ProcessGO:0032922circadian regulation of gene expressionPpargc1aIDAMouseMGI:MGI:3715412|PMID:17476214
Biological ProcessGO:0007005mitochondrion organizationPpargc1aIMPRatRGD:1601465|PMID:17099248
Biological ProcessGO:0007005mitochondrion organizationPpargc1aIMPRatRGD:7242171|PMID:22633948
Biological ProcessGO:0045820negative regulation of glycolytic processPpargc1aIMPRatRGD:7242186|PMID:22343369
Biological ProcessGO:0043524negative regulation of neuron apoptotic processPpargc1aIMPMouseMGI:MGI:4462723|PMID:20566846
Biological ProcessGO:2000272negative regulation of receptor activityPpargc1aIMPRatRGD:6484258|PMID:22593067
Biological ProcessGO:0014912negative regulation of smooth muscle cell migrationPpargc1aIMPRatRGD:8693683|PMID:20955697
Biological ProcessGO:0070997neuron deathPPARGC1AIDAHumanPMID:21376232
Biological ProcessGO:2001171positive regulation of ATP biosynthetic processPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:0031325positive regulation of cellular metabolic processPpargc1aIMPRatRGD:7242177|PMID:22527940
Biological ProcessGO:1901857positive regulation of cellular respirationPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:2000507positive regulation of energy homeostasisPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:0046321positive regulation of fatty acid oxidationPpargc1aIMPRatRGD:1601466|PMID:16139565
Biological ProcessGO:0046321positive regulation of fatty acid oxidationPpargc1aIMPRatRGD:7241851|PMID:23250358
Biological ProcessGO:1901860positive regulation of mitochondrial DNA metabolic processPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:0010822positive regulation of mitochondrion organizationPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:1901863positive regulation of muscle tissue developmentPpargc1aIMPMouseMGI:MGI:5463828|PMID:23150719
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityPPARGC1AIDAHumanPMID:19651776
Biological ProcessGO:0051091positive regulation of sequence-specific DNA binding transcription factor activityPpargc1aIDAMouseMGI:MGI:4418597|PMID:19651776
Biological ProcessGO:0048661positive regulation of smooth muscle cell proliferationPpargc1aIMPRatRGD:7242177|PMID:22527940
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPPARGC1AIDAHumanPMID:21376232
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPpargc1aIGIMGI:MGI:104661|MGI:MGI:1276116MouseMGI:MGI:3053497|PMID:15199055
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPpargc1aIGIMGI:MGI:104740MouseMGI:MGI:4819323|PMID:20385772
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPpargc1aIMPMouseMGI:MGI:4867337|PMID:21106753
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPPARGC1AIDAHumanPMID:16488887
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPPARGC1AIDAHumanPMID:19651776
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPpargc1aIDAMouseMGI:MGI:3032469|PMID:14744933
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPpargc1aIDAMouseMGI:MGI:3529655|PMID:15681609
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPpargc1aIMPRatRGD:1601466|PMID:16139565
Biological ProcessGO:0010941regulation of cell deathPPARGC1AIDAHumanPMID:21376232
Biological ProcessGO:0042752regulation of circadian rhythmPpargc1aIDAMouseMGI:MGI:3715412|PMID:17476214
Biological ProcessGO:2000310regulation of N-methyl-D-aspartate selective glutamate receptor activityPpargc1aIMPRatRGD:6484258|PMID:22593067
Biological ProcessGO:0006355regulation of transcription, DNA-templatedPPARGC1AIDAHumanPMID:23836911
Biological ProcessGO:0022904respiratory electron transport chainPpargc1aIDAMouseMGI:MGI:3032469|PMID:14744933
Biological ProcessGO:0014850response to muscle activityPpargc1aIMPMouseMGI:MGI:4867337|PMID:21106753

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory