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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68265

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:68265

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:68265
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005524ATP bindingPDK2IDAHumanPMID:16401071
Molecular FunctionGO:0005524ATP bindingPdk2IDARatRGD:1582376|PMID:15312755
Molecular FunctionGO:0005524ATP bindingPdk2IMPRatRGD:1582377|PMID:10698691
Molecular FunctionGO:0005524ATP bindingPdk2IDARatRGD:2307429|PMID:12573248
Molecular FunctionGO:0005524ATP bindingPdk2IDARatRGD:68199|PMID:9405293
Molecular FunctionGO:0005515protein bindingPdk2IPIUniProtKB:O08908MouseMGI:MGI:3688344|PMID:15102471
Molecular FunctionGO:0032403protein complex bindingPdk2IDARatRGD:2307429|PMID:12573248
Molecular FunctionGO:0046982protein heterodimerization activityPdk2IDARatRGD:2307429|PMID:12573248
Molecular FunctionGO:0042803protein homodimerization activityPDK2IPIUniProtKB:Q15119HumanPMID:19833728
Molecular FunctionGO:0042803protein homodimerization activityPdk2IDARatRGD:2307429|PMID:12573248
Molecular FunctionGO:0004674protein serine/threonine kinase activityPdk2IDARatRGD:8553418|PMID:11486000
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPDK2EXPHumanPMID:11485553
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPDK2IDAHumanPMID:19833728
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IDARatRGD:1582376|PMID:15312755
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IMPRatRGD:1582377|PMID:10698691
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IDARatRGD:2307429|PMID:12573248
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IDARatRGD:68199|PMID:9405293
Molecular FunctionGO:0004740pyruvate dehydrogenase (acetyl-transferring) kinase activityPdk2IDARatRGD:8553418|PMID:11486000
Cellular ComponentGO:0005829cytosolPDK2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005967mitochondrial pyruvate dehydrogenase complexPdk2IDAMouseMGI:MGI:4888421|PMID:21190881
Cellular ComponentGO:0005739mitochondrionPDK2IDAHumanGO_REF:0000052
Cellular ComponentGO:0005739mitochondrionPdk2IDAMouseMGI:MGI:3852644|PMID:18614015
Cellular ComponentGO:0005739mitochondrionPdk2IDAMouseMGI:MGI:2682130|PMID:14651853
Cellular ComponentGO:0005739mitochondrionPdk2IDAMouseMGI:MGI:4888421|PMID:21190881
Cellular ComponentGO:0005739mitochondrionPdk2IDARatRGD:1582377|PMID:10698691
Cellular ComponentGO:0005654nucleoplasmPDK2IDAHumanGO_REF:0000052
Cellular ComponentGO:0045254pyruvate dehydrogenase complexPdk2IDARatRGD:2307429|PMID:12573248
Biological ProcessGO:0031670cellular response to nutrientPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0034614cellular response to reactive oxygen speciesPDK2IMPHumanPMID:21283817
Biological ProcessGO:0042593glucose homeostasisPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0008286insulin receptor signaling pathwayPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0072332intrinsic apoptotic signaling pathway by p53 class mediatorPDK2IMPHumanPMID:22123926
Biological ProcessGO:0018105peptidyl-serine phosphorylationPdk2IDARatRGD:8553418|PMID:11486000
Biological ProcessGO:0006468protein phosphorylationPdk2IDARatRGD:1582376|PMID:15312755
Biological ProcessGO:0006468protein phosphorylationPdk2IMPRatRGD:1582377|PMID:10698691
Biological ProcessGO:0006468protein phosphorylationPdk2IDARatRGD:2307429|PMID:12573248
Biological ProcessGO:0006468protein phosphorylationPdk2IDARatRGD:68199|PMID:9405293
Biological ProcessGO:0010510regulation of acetyl-CoA biosynthetic process from pyruvatePdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0010565regulation of cellular ketone metabolic processPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0006111regulation of gluconeogenesisPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0010906regulation of glucose metabolic processPdk2IMPMouseMGI:MGI:5428826|PMID:22360721
Biological ProcessGO:0006885regulation of pHPdk2IMPMouseMGI:MGI:5428826|PMID:22360721

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory