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Comparative GO Graph (mouse, human, rat)
Class ID
HomoloGene (Release 68, May 6, 2014)

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:55803

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:55803
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004449isocitrate dehydrogenase (NAD+) activityIdh3gIDARatRGD:2306828|PMID:938457
Cellular ComponentGO:0005739mitochondrionIDH3GIDAHumanGO_REF:0000052
Cellular ComponentGO:0005739mitochondrionIDH3GIDAHumanGO_REF:0000054
Cellular ComponentGO:0005739mitochondrionIdh3gIDAMouseMGI:MGI:2682130|PMID:14651853
Cellular ComponentGO:0005739mitochondrionIdh3gIDAMouseMGI:MGI:3852644|PMID:18614015
Cellular ComponentGO:0005730nucleolusIDH3GIDAHumanGO_REF:0000052
Cellular ComponentGO:0005654nucleoplasmIDH3GIDAHumanGO_REF:0000052
Biological ProcessGO:00061032-oxoglutarate metabolic processIdh3gIDARatRGD:2306828|PMID:938457
Biological ProcessGO:0006102isocitrate metabolic processIdh3gIDARatRGD:2306828|PMID:938457
Biological ProcessGO:0006734NADH metabolic processIdh3gIDARatRGD:2306828|PMID:938457
Biological ProcessGO:0045926negative regulation of growthIdh3gIMPRatRGD:633076|PMID:9126338
Biological ProcessGO:0006099tricarboxylic acid cycleIdh3gIDARatRGD:2306828|PMID:938457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory