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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
55526

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:55526

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:55526
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005125cytokine activityIfngIDAMouseMGI:MGI:2664488|PMID:11911824
Molecular FunctionGO:0005125cytokine activityIfngIDAMouseMGI:MGI:2673020|PMID:12925700
Molecular FunctionGO:0005125cytokine activityIfngIDAMouseMGI:MGI:3033882|PMID:11027433
Molecular FunctionGO:0005125cytokine activityIfngIDAMouseMGI:MGI:3051174|PMID:15240719
Molecular FunctionGO:0005515protein bindingIfngIPIUniProtKB:P52293MouseMGI:MGI:3795810|PMID:18405666
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:3700858|PMID:16177108
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:3718932|PMID:17658279
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:4436838|PMID:19838199
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:4454353|PMID:20399120
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:4838928|PMID:20956546
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:4887510|PMID:21217760
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:5013872|PMID:21606376
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:5085959|PMID:21709260
Cellular ComponentGO:0009897external side of plasma membraneIfngIDAMouseMGI:MGI:5287957|PMID:21613615
Cellular ComponentGO:0005576extracellular regionIFNGIDAHumanPMID:20041150
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:1332382|PMID:10072077
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:1926579|PMID:11057672
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:2176422|PMID:11894098
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3050756|PMID:15220916
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3051177|PMID:15240714
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3510555|PMID:11728336
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3653161|PMID:9348310
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3693968|PMID:16769892
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3695768|PMID:16275384
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3813999|PMID:17082577
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3823129|PMID:18997793
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3829555|PMID:17277142
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:3839525|PMID:19139201
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:4838368|PMID:20706986
Cellular ComponentGO:0005615extracellular spaceIfngIDAMouseMGI:MGI:5004747|PMID:21460847
Cellular ComponentGO:0005615extracellular spaceIfngIDARatRGD:2311497|PMID:2474612
Cellular ComponentGO:0005615extracellular spaceIfngIDARatRGD:729159|PMID:3924594
Biological ProcessGO:0002250adaptive immune responseIfngIDAMouseMGI:MGI:3829555|PMID:17277142
Biological ProcessGO:0019882antigen processing and presentationIfngIDAMouseMGI:MGI:3054461|PMID:15356141
Biological ProcessGO:0006915apoptotic processIFNGIGIUniProtKB:P51397HumanPMID:7828849
Biological ProcessGO:0006915apoptotic processIFNGIGIUniProtKB:P53355HumanPMID:7828849
Biological ProcessGO:0002302CD8-positive, alpha-beta T cell differentiation involved in immune responseIfngIDAMouseMGI:MGI:3829555|PMID:17277142
Biological ProcessGO:0007050cell cycle arrestIFNGIDAHumanPMID:16942485
Biological ProcessGO:0071351cellular response to interleukin-18IfngIDAMouseMGI:MGI:4355633|PMID:19666510
Biological ProcessGO:0071222cellular response to lipopolysaccharideIfngIDAMouseMGI:MGI:3821815|PMID:18791161
Biological ProcessGO:0042742defense response to bacteriumIfngIDAMouseMGI:MGI:3051174|PMID:15240719
Biological ProcessGO:0042832defense response to protozoanIfngIMPMGI:MGI:1857184MouseMGI:MGI:3653161|PMID:9348310
Biological ProcessGO:0051607defense response to virusIfngIDAMouseMGI:MGI:4431293|PMID:20064371
Biological ProcessGO:0030968endoplasmic reticulum unfolded protein responseIfngIDAMouseMGI:MGI:3583403|PMID:15911877
Biological ProcessGO:0097191extrinsic apoptotic signaling pathwayIFNGIDAHumanPMID:16942485
Biological ProcessGO:0006959humoral immune responseIfngIDAMouseMGI:MGI:3829555|PMID:17277142
Biological ProcessGO:0006925inflammatory cell apoptotic processIfngIMPMouseMGI:MGI:3027059|PMID:11457893
Biological ProcessGO:0008285negative regulation of cell proliferationIfngIDARatRGD:1300182|PMID:11940252
Biological ProcessGO:0044130negative regulation of growth of symbiont in hostIfngIMPMGI:MGI:1857184MouseMGI:MGI:3653161|PMID:9348310
Biological ProcessGO:0044146negative regulation of growth of symbiont involved in interaction with hostIfngIDAMouseMGI:MGI:3653161|PMID:9348310
Biological ProcessGO:0032700negative regulation of interleukin-17 productionIFNGIDAHumanPMID:18501882
Biological ProcessGO:0003340negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0003340negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisIfngIDARatPMID:20624457
Biological ProcessGO:0072308negative regulation of metanephric nephron tubule epithelial cell differentiationIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0072308negative regulation of metanephric nephron tubule epithelial cell differentiationIfngIDARatPMID:20624457
Biological ProcessGO:0031642negative regulation of myelinationIfngIDAMouseMGI:MGI:3583403|PMID:15911877
Biological ProcessGO:0048662negative regulation of smooth muscle cell proliferationIFNGIDAHumanPMID:16942485
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIfngIDARatPMID:20624457
Biological ProcessGO:0001781neutrophil apoptotic processIfngIMPMGI:MGI:1857184MouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0030593neutrophil chemotaxisIfngIDAMouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0030593neutrophil chemotaxisIfngIMPMGI:MGI:1857184MouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0060559positive regulation of calcidiol 1-monooxygenase activityIFNGIDAHumanPMID:9282826
Biological ProcessGO:0045785positive regulation of cell adhesionIfngIDARatRGD:2311500|PMID:2509328
Biological ProcessGO:0045080positive regulation of chemokine biosynthetic processIfngIDAMouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0045080positive regulation of chemokine biosynthetic processIfngIMPMGI:MGI:1857184MouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0060550positive regulation of fructose 1,6-bisphosphate 1-phosphatase activityIFNGIDAHumanPMID:9282826
Biological ProcessGO:0060552positive regulation of fructose 1,6-bisphosphate metabolic processIFNGIDAHumanPMID:9282826
Biological ProcessGO:0050718positive regulation of interleukin-1 beta secretionIfngIMPMGI:MGI:1857184MouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0045084positive regulation of interleukin-12 biosynthetic processIfngIDAMouseMGI:MGI:2679145|PMID:14568984
Biological ProcessGO:0032735positive regulation of interleukin-12 productionIFNGIDAHumanPMID:7605994
Biological ProcessGO:0032735positive regulation of interleukin-12 productionIFNGIDAHumanPMID:8557999
Biological ProcessGO:0032735positive regulation of interleukin-12 productionIfngIDAMouseMGI:MGI:3653161|PMID:9348310
Biological ProcessGO:0032747positive regulation of interleukin-23 productionIFNGIDAHumanPMID:20027291
Biological ProcessGO:0045410positive regulation of interleukin-6 biosynthetic processIfngIDAMouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0045410positive regulation of interleukin-6 biosynthetic processIfngIMPMGI:MGI:1857184MouseMGI:MGI:2673020|PMID:12925700
Biological ProcessGO:0048304positive regulation of isotype switching to IgG isotypesIfngIDAMouseMGI:MGI:2670820|PMID:12882831
Biological ProcessGO:0051712positive regulation of killing of cells of other organismIFNGIDAHumanPMID:7544003
Biological ProcessGO:0051044positive regulation of membrane protein ectodomain proteolysisIFNGIDAHumanPMID:18373975
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIfngIDARatPMID:20624457
Biological ProcessGO:0045348positive regulation of MHC class II biosynthetic processIfngIDAMouseMGI:MGI:3033882|PMID:11027433
Biological ProcessGO:0045348positive regulation of MHC class II biosynthetic processIfngIDAMouseMGI:MGI:4942276|PMID:2502420
Biological ProcessGO:0045348positive regulation of MHC class II biosynthetic processIfngIDAMouseMGI:MGI:4942277|PMID:2493384
Biological ProcessGO:0045348positive regulation of MHC class II biosynthetic processIfngIDAMouseMGI:MGI:4943415|PMID:1845803
Biological ProcessGO:0045666positive regulation of neuron differentiationIfngIDARatRGD:2311496|PMID:19355840
Biological ProcessGO:0045429positive regulation of nitric oxide biosynthetic processIFNGIDAHumanPMID:8383325
Biological ProcessGO:0045429positive regulation of nitric oxide biosynthetic processIfngIDAMouseMGI:MGI:1930064|PMID:11168643
Biological ProcessGO:0045672positive regulation of osteoclast differentiationIFNGIDAHumanPMID:16220542
Biological ProcessGO:0033141positive regulation of peptidyl-serine phosphorylation of STAT proteinIFNGIDAHumanPMID:16280321
Biological ProcessGO:0033141positive regulation of peptidyl-serine phosphorylation of STAT proteinIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0033141positive regulation of peptidyl-serine phosphorylation of STAT proteinIfngIDARatPMID:20624457
Biological ProcessGO:0034393positive regulation of smooth muscle cell apoptotic processIFNGIDAHumanPMID:16942485
Biological ProcessGO:0032224positive regulation of synaptic transmission, cholinergicIfngIDARatRGD:2311499|PMID:1900518
Biological ProcessGO:0042102positive regulation of T cell proliferationIfngIDAMouseMGI:MGI:3621255|PMID:16280321
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIfngIDAMouseMGI:MGI:4412460|PMID:18025219
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIfngIGIMGI:MGI:104798MouseMGI:MGI:4412460|PMID:18025219
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedIfngIDAMouseMGI:MGI:2679145|PMID:14568984
Biological ProcessGO:2000309positive regulation of tumor necrosis factor (ligand) superfamily member 11 productionIFNGIDAHumanPMID:16220542
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionIfngIDAMouseMGI:MGI:4942276|PMID:2502420
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionIfngIDAMouseMGI:MGI:4943415|PMID:1845803
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinIFNGIDAHumanPMID:15604419
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinIFNGIDAHumanPMID:16280321
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinIfngIDARatRGD:8554478|PMID:20624457
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinIfngIDARatPMID:20624457
Biological ProcessGO:0060557positive regulation of vitamin D biosynthetic processIFNGIDAHumanPMID:9282826
Biological ProcessGO:0000060protein import into nucleus, translocationIFNGIDAHumanPMID:15604419
Biological ProcessGO:2000345regulation of hepatocyte proliferationIfngIDARatRGD:8142374|PMID:15799032
Biological ProcessGO:0050776regulation of immune responseIfngIDAMouseMGI:MGI:2670820|PMID:12882831
Biological ProcessGO:0050796regulation of insulin secretionIFNGIDAHumanPMID:8383325
Biological ProcessGO:0098908regulation of neuronal action potentialIfngIDARatRGD:8158038|PMID:7715823
Biological ProcessGO:0002026regulation of the force of heart contractionIfngIDARatRGD:2311499|PMID:1900518
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIfngIDAMouseMGI:MGI:2385392|PMID:12050152
Biological ProcessGO:0009615response to virusIFNGIDAHumanPMID:16280321
Biological ProcessGO:0050954sensory perception of mechanical stimulusIfngIDARatRGD:8158038|PMID:7715823

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory