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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
543

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:543

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:543
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0042166acetylcholine bindingACHEIDAHumanPMID:8349597
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301187|PMID:1133098
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301195|PMID:126256
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301203|PMID:4008917
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301204|PMID:3655326
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301205|PMID:2731551
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301207|PMID:8737018
Molecular FunctionGO:0042166acetylcholine bindingAcheIDARatRGD:2301213|PMID:14646156
Molecular FunctionGO:0003990acetylcholinesterase activityACHEIDAHumanPMID:1517212
Molecular FunctionGO:0003990acetylcholinesterase activityACHEIMPHumanPMID:1517212
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDAMouseMGI:MGI:3654414|PMID:16434405
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDAMouseMGI:MGI:65815|PMID:7512968
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:1580870|PMID:16052514
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301187|PMID:1133098
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301195|PMID:126256
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301197|PMID:334962
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301199|PMID:6854006
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301203|PMID:4008917
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301204|PMID:3655326
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301205|PMID:2731551
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301207|PMID:8737018
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:2301213|PMID:14646156
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIMPRatRGD:2301214|PMID:17018647
Molecular FunctionGO:0003990acetylcholinesterase activityAcheIDARatRGD:724758|PMID:8417155
Molecular FunctionGO:0033265choline bindingAcheIDARatRGD:2301187|PMID:1133098
Molecular FunctionGO:0004104cholinesterase activityACHEIDAHumanPMID:1517212
Molecular FunctionGO:0005518collagen bindingACHEIDAHumanPMID:12524166
Molecular FunctionGO:0016787hydrolase activityACHEIDAHumanPMID:1517212
Molecular FunctionGO:0043236laminin bindingACHEIDAHumanPMID:12524166
Molecular FunctionGO:0043236laminin bindingAcheIPIUniProtKB:P02469MouseMGI:MGI:3056824|PMID:15474030
Molecular FunctionGO:0005515protein bindingACHEIPIUniProtKB:O60888HumanPMID:10800960
Molecular FunctionGO:0005515protein bindingACHEIPIUniProtKB:Q9Y215HumanPMID:15526038
Molecular FunctionGO:0005515protein bindingACHEIPIUniProtKB:P06733HumanPMID:18194455
Molecular FunctionGO:0005515protein bindingACHEIPIUniProtKB:P63244HumanPMID:18194455
Molecular FunctionGO:0005515protein bindingAcheIPIUniProtKB:O35348MouseMGI:MGI:4431306|PMID:20053883
Molecular FunctionGO:0042803protein homodimerization activityACHEIPIUniProtKB:P22303HumanPMID:12524166
Molecular FunctionGO:0043621protein self-associationAcheIPIUniProtKB:P21836MouseMGI:MGI:78969|PMID:8626792
Molecular FunctionGO:0017171serine hydrolase activityACHEIDAHumanPMID:3954986
Cellular ComponentGO:0030424axonAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0005605basal laminaAcheIDAMouseMGI:MGI:71472|PMID:7885444
Cellular ComponentGO:0009986cell surfaceAcheIDAMouseMGI:MGI:3654414|PMID:16434405
Cellular ComponentGO:0009986cell surfaceAcheIDARatRGD:2301205|PMID:2731551
Cellular ComponentGO:0005737cytoplasmAcheIDARatRGD:1580870|PMID:16052514
Cellular ComponentGO:0030425dendriteAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0005788endoplasmic reticulum lumenAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0005576extracellular regionACHEIDAHumanPMID:1517212
Cellular ComponentGO:0005615extracellular spaceAcheIDAMouseMGI:MGI:3654414|PMID:16434405
Cellular ComponentGO:0005615extracellular spaceAcheIDAMouseMGI:MGI:78969|PMID:8626792
Cellular ComponentGO:0005794Golgi apparatusACHEIDAHumanPMID:15454088
Cellular ComponentGO:0005794Golgi apparatusAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0016020membraneACHEIDAHumanPMID:16262697
Cellular ComponentGO:0031594neuromuscular junctionAcheIDAMouseMGI:MGI:71472|PMID:7885444
Cellular ComponentGO:0043005neuron projectionAcheIDARatRGD:1580870|PMID:16052514
Cellular ComponentGO:0043025neuronal cell bodyAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0005635nuclear envelopeAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0048471perinuclear region of cytoplasmACHEIDAHumanPMID:14766237
Cellular ComponentGO:0048471perinuclear region of cytoplasmAcheIDARatRGD:1580870|PMID:16052514
Cellular ComponentGO:0005886plasma membraneAcheIDAMouseMGI:MGI:78969|PMID:8626792
Cellular ComponentGO:0005886plasma membraneAcheIDARatRGD:2301205|PMID:2731551
Cellular ComponentGO:0045211postsynaptic membraneAcheIDARatRGD:2301204|PMID:3655326
Cellular ComponentGO:0042734presynaptic membraneAcheIDARatRGD:2301204|PMID:3655326
Cellular ComponentGO:0005791rough endoplasmic reticulumAcheIDARatRGD:2301205|PMID:2731551
Cellular ComponentGO:0045202synapseACHEIDAHumanPMID:8460160
Cellular ComponentGO:0045202synapseAcheIDAMouseMGI:MGI:2449890|PMID:12533614
Cellular ComponentGO:0045202synapseAcheIDAMouseMGI:MGI:2179537|PMID:10995443
Cellular ComponentGO:0045202synapseAcheIDARatRGD:2301187|PMID:1133098
Cellular ComponentGO:0043083synaptic cleftAcheIDARatRGD:12050110|PMID:26820598
Biological ProcessGO:0006581acetylcholine catabolic processACHEIDAHumanPMID:1517212
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDAMouseMGI:MGI:65815|PMID:7512968
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDAMouseMGI:MGI:3654414|PMID:16434405
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:1580870|PMID:16052514
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301187|PMID:1133098
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301195|PMID:126256
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301197|PMID:334962
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301199|PMID:6854006
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301203|PMID:4008917
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301204|PMID:3655326
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301205|PMID:2731551
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301207|PMID:8737018
Biological ProcessGO:0006581acetylcholine catabolic processAcheIDARatRGD:2301213|PMID:14646156
Biological ProcessGO:0006581acetylcholine catabolic processAcheIMPRatRGD:2301214|PMID:17018647
Biological ProcessGO:0008291acetylcholine metabolic processAcheIMPRatRGD:1580871|PMID:16628397
Biological ProcessGO:0007155cell adhesionACHEIDAHumanPMID:15454088
Biological ProcessGO:0019695choline metabolic processAcheIMPRatRGD:1580871|PMID:16628397
Biological ProcessGO:0019695choline metabolic processAcheIDARatRGD:2301187|PMID:1133098
Biological ProcessGO:0019695choline metabolic processAcheIDARatRGD:2301207|PMID:8737018
Biological ProcessGO:0070997neuron deathAcheIMPRatRGD:5510037|PMID:11403956
Biological ProcessGO:0045212neurotransmitter receptor biosynthetic processAcheIMPMGI:MGI:2179948MouseMGI:MGI:3609472|PMID:14645660
Biological ProcessGO:0050772positive regulation of axonogenesisAcheIMPRatRGD:1299197|PMID:12799140
Biological ProcessGO:0050775positive regulation of dendrite morphogenesisAcheIMPRatRGD:1299197|PMID:12799140
Biological ProcessGO:0051262protein tetramerizationAcheIDAMouseMGI:MGI:78969|PMID:8626792
Biological ProcessGO:0031623receptor internalizationAcheIMPMGI:MGI:2179948MouseMGI:MGI:3609472|PMID:14645660
Biological ProcessGO:0001919regulation of receptor recyclingAcheIMPMGI:MGI:2179948MouseMGI:MGI:3609472|PMID:14645660
Biological ProcessGO:0060041retina development in camera-type eyeAcheIMPMGI:MGI:2179948MouseMGI:MGI:3603700|PMID:15579149
Biological ProcessGO:0007416synapse assemblyAcheIMPRatRGD:1299197|PMID:12799140

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory