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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
40606

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:40606

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:40606
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0030165PDZ domain bindingFZD8IPIUniProtKB:O00560HumanPMID:18256285
Molecular FunctionGO:0030165PDZ domain bindingFzd8IPIUniProtKB:Q8BH60MouseMGI:MGI:3688061|PMID:11520064
Molecular FunctionGO:0005515protein bindingFZD8IPIUniProtKB:P56704HumanPMID:22682250
Molecular FunctionGO:0005515protein bindingFZD8IPIUniProtKB:P98086HumanPMID:22682250
Molecular FunctionGO:0005515protein bindingFzd8IPIUniProtKB:Q01887MouseMGI:MGI:3510085|PMID:15454084
Molecular FunctionGO:0005515protein bindingFzd8IPIUniProtKB:Q9Z132|UniProtKB:Q2TJ95MouseMGI:MGI:3664518|PMID:16543246
Molecular FunctionGO:0005515protein bindingFzd8IPIUniProtKB:Q8BH60MouseMGI:MGI:3688061|PMID:11520064
Molecular FunctionGO:0005102receptor bindingFzd8IPIUniProtKB:O75581MouseMGI:MGI:4839462|PMID:11029007
Molecular FunctionGO:0031625ubiquitin protein ligase bindingFZD8IPIUniProtKB:Q9ULT6HumanPMID:22575959
Molecular FunctionGO:0042813Wnt-activated receptor activityFzd8IPIUniProtKB:P04426MouseMGI:MGI:3510085|PMID:15454084
Molecular FunctionGO:0017147Wnt-protein bindingFzd8IPIUniProtKB:P04426MouseMGI:MGI:3510085|PMID:15454084
Cellular ComponentGO:0005886plasma membraneFzd8IDAMouseMGI:MGI:3621833|PMID:15035989
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd8IMPMouseMGI:MGI:1929591|PMID:11265645
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd8IMPMouseMGI:MGI:3045540|PMID:15064719
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd8IMPMouseMGI:MGI:3045675|PMID:15143170
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd8IGIMGI:MGI:98956MouseMGI:MGI:3619748|PMID:16115200
Biological ProcessGO:0060070canonical Wnt signaling pathwayFzd8IDAMouseMGI:MGI:3664518|PMID:16543246
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterFzd8IDAMouseMGI:MGI:3703823|PMID:17360443
Biological ProcessGO:0043507positive regulation of JUN kinase activityFzd8IDAMouseMGI:MGI:4829604|PMID:15195140
Biological ProcessGO:0001934positive regulation of protein phosphorylationFzd8IMPMouseMGI:MGI:3045675|PMID:15143170
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterFzd8IDAMouseMGI:MGI:3703823|PMID:17360443
Biological ProcessGO:0007165signal transductionFzd8IPIUniProtKB:P04426MouseMGI:MGI:3510085|PMID:15454084
Biological ProcessGO:0033077T cell differentiation in thymusFzd8IMPMouseMGI:MGI:1929591|PMID:11265645

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory