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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
36321

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:36321

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:36321
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005125cytokine activityTIMP1IDAHumanPMID:3839290
Molecular FunctionGO:0008191metalloendopeptidase inhibitor activityTIMP1IDAHumanPMID:12714508
Molecular FunctionGO:0008191metalloendopeptidase inhibitor activityTIMP1IDAHumanPMID:3903517
Molecular FunctionGO:0008191metalloendopeptidase inhibitor activityTIMP1IDAHumanPMID:9573338
Molecular FunctionGO:0002020protease bindingTimp1IPIRGD:1307917RatRGD:7207284|PMID:21846328
Molecular FunctionGO:0005515protein bindingTIMP1IPIUniProtKB:P08962HumanPMID:16917503
Molecular FunctionGO:0005515protein bindingTIMP1IPIUniProtKB:P14780HumanPMID:2251898
Molecular FunctionGO:0005515protein bindingTIMP1IPIUniProtKB:P14780HumanPMID:24330623
Cellular ComponentGO:0005604basement membraneTimp1IDAMouseMGI:MGI:2675517|PMID:12950084
Cellular ComponentGO:0070062extracellular exosomeTIMP1IDAHumanPMID:23376485
Cellular ComponentGO:0070062extracellular exosomeTIMP1IDAHumanPMID:23533145
Cellular ComponentGO:0031012extracellular matrixTimp1IDARatRGD:2290365|PMID:9579471
Cellular ComponentGO:0005615extracellular spaceTIMP1IDAHumanPMID:3903517
Cellular ComponentGO:0005615extracellular spaceTimp1IDAMouseMGI:MGI:5640941|PMID:24006456
Cellular ComponentGO:0005578proteinaceous extracellular matrixTimp1IDAMouseMGI:MGI:2675517|PMID:12950084
Biological ProcessGO:0001775cell activationTimp1IMPRatRGD:1580120|PMID:15389776
Biological ProcessGO:0043066negative regulation of apoptotic processTimp1IMPRatRGD:1580121|PMID:12081564
Biological ProcessGO:0043086negative regulation of catalytic activityTIMP1IDAHumanPMID:3903517
Biological ProcessGO:0010951negative regulation of endopeptidase activityTIMP1IDAHumanPMID:3903517
Biological ProcessGO:0051045negative regulation of membrane protein ectodomain proteolysisTIMP1IDAHumanPMID:12714508
Biological ProcessGO:1905049negative regulation of metallopeptidase activityTIMP1IDAHumanPMID:9573338
Biological ProcessGO:1901164negative regulation of trophoblast cell migrationTIMP1IMPHumanPMID:21356369
Biological ProcessGO:0008284positive regulation of cell proliferationTIMP1IDAHumanPMID:3839290
Biological ProcessGO:2001044regulation of integrin-mediated signaling pathwayTIMP1IMPHumanPMID:16917503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory