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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
328

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:328

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:328
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0017127cholesterol transporter activityAPOBIMPHumanPMID:15797858
Molecular FunctionGO:0008201heparin bindingAPOBIDAHumanPMID:16233946
Molecular FunctionGO:0035473lipase bindingAPOBIPIUniProtKB:P07867HumanPMID:9685400
Molecular FunctionGO:0008289lipid bindingApobIMPRatRGD:1626402|PMID:12091487
Molecular FunctionGO:0050750low-density lipoprotein particle receptor bindingAPOBIMPHumanPMID:15797858
Molecular FunctionGO:0050750low-density lipoprotein particle receptor bindingAPOBIMPHumanPMID:2563166
Molecular FunctionGO:0005543phospholipid bindingAPOBIDAHumanPMID:7126555
Molecular FunctionGO:0005515protein bindingAPOBIPIUniProtKB:P29991:PRO_0000037946HumanPMID:21911577
Molecular FunctionGO:0005515protein bindingAPOBIPIUniProtKB:Q8NBP7HumanPMID:22580899
Molecular FunctionGO:0005515protein bindingAPOBIPIUniProtKB:P01130HumanPMID:24447298
Molecular FunctionGO:0005515protein bindingAPOBIPIUniProtKB:P02652HumanPMID:8245722
Molecular FunctionGO:0005515protein bindingApobIPIRGD:1308388RatRGD:1582567|PMID:11830580
Cellular ComponentGO:0015629actin cytoskeletonAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0015629actin cytoskeletonAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0042627chylomicronAPOBIDAHumanPMID:4363408
Cellular ComponentGO:0042627chylomicronAPOBIDAHumanPMID:8245722
Cellular ComponentGO:0005737cytoplasmAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0005737cytoplasmAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0005737cytoplasmAPOBIDAHumanPMID:22580899
Cellular ComponentGO:0005783endoplasmic reticulumApobIDAMouseMGI:MGI:2386141|PMID:12072432
Cellular ComponentGO:0005615extracellular spaceApobIDARatRGD:1599170|PMID:16227197
Cellular ComponentGO:0005794Golgi apparatusAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0005794Golgi apparatusAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0034363intermediate-density lipoprotein particleAPOBIDAHumanPMID:1917954
Cellular ComponentGO:0043231intracellular membrane-bounded organelleApobIDARatRGD:1626402|PMID:12091487
Cellular ComponentGO:0034362low-density lipoprotein particleAPOBIDAHumanPMID:4363408
Cellular ComponentGO:0034359mature chylomicronAPOBIDAHumanPMID:4363408
Cellular ComponentGO:0005886plasma membraneAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneAPOBIDAHumanGO_REF:0000052
Cellular ComponentGO:0034361very-low-density lipoprotein particleAPOBIDAHumanPMID:15308631
Cellular ComponentGO:0034361very-low-density lipoprotein particleAPOBIDAHumanPMID:4363408
Cellular ComponentGO:0034361very-low-density lipoprotein particleApobIDARatRGD:2325767|PMID:17500069
Cellular ComponentGO:0031983vesicle lumenApobIDARatRGD:1626402|PMID:12091487
Cellular ComponentGO:0012506vesicle membraneApobIDARatRGD:1626402|PMID:12091487
Biological ProcessGO:0048844artery morphogenesisApobIGIMGI:MGI:88057MouseMGI:MGI:3695082|PMID:16230502
Biological ProcessGO:0033344cholesterol effluxApobIGIMGI:MGI:104539MouseMGI:MGI:5428098|PMID:22363685
Biological ProcessGO:0042632cholesterol homeostasisAPOBIMPHumanPMID:2563166
Biological ProcessGO:0042632cholesterol homeostasisApobIMPMGI:MGI:1857625MouseMGI:MGI:71076|PMID:7878058
Biological ProcessGO:0042632cholesterol homeostasisApobIMPMGI:MGI:3665449MouseMGI:MGI:83856|PMID:8921909
Biological ProcessGO:0042632cholesterol homeostasisApobIMPMGI:MGI:1857304|MGI:MGI:1857303MouseMGI:MGI:893988|PMID:9202070
Biological ProcessGO:0042632cholesterol homeostasisApobIMPMGI:MGI:1857304MouseMGI:MGI:1201298|PMID:9502790
Biological ProcessGO:0042632cholesterol homeostasisApobIMPMGI:MGI:2157108MouseMGI:MGI:1316893|PMID:9852051
Biological ProcessGO:0042632cholesterol homeostasisApobIGIMGI:MGI:88057|MGI:MGI:96765MouseMGI:MGI:1928445|PMID:11120757
Biological ProcessGO:0042632cholesterol homeostasisApobIGIMGI:MGI:88057MouseMGI:MGI:3695082|PMID:16230502
Biological ProcessGO:0008203cholesterol metabolic processAPOBIMPHumanPMID:2563166
Biological ProcessGO:0030301cholesterol transportAPOBIMPHumanPMID:2563166
Biological ProcessGO:0030301cholesterol transportApobIMPMGI:MGI:2157090MouseMGI:MGI:77225|PMID:7593600
Biological ProcessGO:0009566fertilizationApobIMPMGI:MGI:2157090MouseMGI:MGI:83280|PMID:8855280
Biological ProcessGO:0001701in utero embryonic developmentApobIMPMGI:MGI:1857625MouseMGI:MGI:71076|PMID:7878058
Biological ProcessGO:0001701in utero embryonic developmentApobIMPMGI:MGI:2157775MouseMGI:MGI:1201298|PMID:9502790
Biological ProcessGO:0016042lipid catabolic processApobIMPMGI:MGI:2183298MouseMGI:MGI:3652707|PMID:16455790
Biological ProcessGO:0006629lipid metabolic processApobIMPMGI:MGI:1857141MouseMGI:MGI:64433|PMID:8460149
Biological ProcessGO:0006629lipid metabolic processApobIGIMGI:MGI:88057|MGI:MGI:96765MouseMGI:MGI:1928445|PMID:11120757
Biological ProcessGO:0006629lipid metabolic processApobIDAMouseMGI:MGI:2386141|PMID:12072432
Biological ProcessGO:0006629lipid metabolic processApobIMPMGI:MGI:2183298MouseMGI:MGI:3612778|PMID:15790761
Biological ProcessGO:0006629lipid metabolic processApobIDARatRGD:1626403|PMID:9931432
Biological ProcessGO:0042158lipoprotein biosynthetic processApobIGIMGI:MGI:103298MouseMGI:MGI:3028770|PMID:13130124
Biological ProcessGO:0042159lipoprotein catabolic processApobIGIMGI:MGI:107202MouseMGI:MGI:3588634|PMID:15863839
Biological ProcessGO:0042157lipoprotein metabolic processApobIMPMGI:MGI:1857625MouseMGI:MGI:71076|PMID:7878058
Biological ProcessGO:0042157lipoprotein metabolic processApobIMPMGI:MGI:2157108MouseMGI:MGI:1316893|PMID:9852051
Biological ProcessGO:0042157lipoprotein metabolic processApobIMPMGI:MGI:1857303MouseMGI:MGI:1354526|PMID:10713055
Biological ProcessGO:0042157lipoprotein metabolic processApobIGIMGI:MGI:88057|MGI:MGI:96765MouseMGI:MGI:1928445|PMID:11120757
Biological ProcessGO:0042157lipoprotein metabolic processApobIGIMGI:MGI:88057MouseMGI:MGI:3028770|PMID:13130124
Biological ProcessGO:0042157lipoprotein metabolic processApobIGIMGI:MGI:96765MouseMGI:MGI:3028770|PMID:13130124
Biological ProcessGO:0042157lipoprotein metabolic processApobIMPMGI:MGI:3665449MouseMGI:MGI:3664699|PMID:10705993
Biological ProcessGO:0042953lipoprotein transportApobIMPMGI:MGI:2183298MouseMGI:MGI:3028770|PMID:13130124
Biological ProcessGO:0042953lipoprotein transportApobIGIMGI:MGI:103298MouseMGI:MGI:3028770|PMID:13130124
Biological ProcessGO:0034383low-density lipoprotein particle clearanceAPOBIMPHumanPMID:15797858
Biological ProcessGO:0034383low-density lipoprotein particle clearanceAPOBIMPHumanPMID:2563166
Biological ProcessGO:0034374low-density lipoprotein particle remodelingAPOBIMPHumanPMID:15797858
Biological ProcessGO:0007399nervous system developmentApobIMPMGI:MGI:1857625MouseMGI:MGI:71076|PMID:7878058
Biological ProcessGO:0007399nervous system developmentApobIMPMGI:MGI:3665449MouseMGI:MGI:83856|PMID:8921909
Biological ProcessGO:0007399nervous system developmentApobIMPMGI:MGI:2157775MouseMGI:MGI:1201298|PMID:9502790
Biological ProcessGO:0010886positive regulation of cholesterol storageAPOBIDAHumanPMID:19114110
Biological ProcessGO:0010884positive regulation of lipid storageAPOBIDAHumanPMID:18322245
Biological ProcessGO:0010744positive regulation of macrophage derived foam cell differentiationAPOBIDAHumanPMID:17244792
Biological ProcessGO:0010744positive regulation of macrophage derived foam cell differentiationAPOBIDAHumanPMID:18322245
Biological ProcessGO:0010744positive regulation of macrophage derived foam cell differentiationAPOBIDAHumanPMID:19114110
Biological ProcessGO:0009791post-embryonic developmentApobIMPMGI:MGI:2157108MouseMGI:MGI:1316893|PMID:9852051
Biological ProcessGO:0045540regulation of cholesterol biosynthetic processApobIMPMGI:MGI:2183298MouseMGI:MGI:3652707|PMID:16455790
Biological ProcessGO:0009743response to carbohydrateApobIDARatRGD:1599166|PMID:16672736
Biological ProcessGO:0030317sperm motilityApobIMPMGI:MGI:2157090MouseMGI:MGI:83280|PMID:8855280
Biological ProcessGO:0007283spermatogenesisApobIMPMGI:MGI:2157090MouseMGI:MGI:83280|PMID:8855280
Biological ProcessGO:0019433triglyceride catabolic processApobIMPMGI:MGI:2183298MouseMGI:MGI:3652707|PMID:16455790
Biological ProcessGO:0019433triglyceride catabolic processApobIMPRatRGD:1626404|PMID:9290048
Biological ProcessGO:0006642triglyceride mobilizationApobIMPMGI:MGI:2183298MouseMGI:MGI:1913181|PMID:10893242

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory