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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
31141

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:31141

Graphs for Molecular Function, Cellular Component, Biological Process generated Wed Mar 2 12:12:49 2016.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:31141
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003677DNA bindingTERTIDAHumanPMID:21937513
Molecular FunctionGO:0016779nucleotidyltransferase activityTERTIDAHumanPMID:19701182
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96BK5HumanPMID:11701125
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:P12956HumanPMID:12377759
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:P13010HumanPMID:12377759
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q86US8HumanPMID:12699629
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9UPR3HumanPMID:12699629
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96EZ8-2HumanPMID:15044100
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96BK5HumanPMID:15381700
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q86US8HumanPMID:15857955
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9UPR3HumanPMID:15857955
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96AP0HumanPMID:17237767
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q86US8HumanPMID:17940095
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9H0A0HumanPMID:18082603
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9Y265HumanPMID:18358808
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9BUR4HumanPMID:19179534
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9NVN8HumanPMID:19487455
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:P29590-5HumanPMID:19567472
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96BK5HumanPMID:21119197
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q92900HumanPMID:21829167
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:O15381HumanPMID:22226966
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9BVP2HumanPMID:24550003
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q96AP0HumanPMID:25172512
Molecular FunctionGO:0005515protein bindingTERTIPIUniProtKB:Q9BQ15HumanPMID:25589350
Molecular FunctionGO:0005515protein bindingTertIPIUniProtKB:Q9CZX5MouseMGI:MGI:2153155|PMID:11701125
Molecular FunctionGO:0005515protein bindingTertIPIPR:Q80SX8-1MouseMGI:MGI:3699074|PMID:17130244
Molecular FunctionGO:0005515protein bindingTertIPIUniProtKB:P17809|UniProtKB:P14142|UniProtKB:Q8BFW9MouseMGI:MGI:5616266|PMID:24970747
Molecular FunctionGO:0042803protein homodimerization activityTERTIDAHumanPMID:11432839
Molecular FunctionGO:0003723RNA bindingTERTIPIRNAcentral:URS000075C8FA_9606HumanPMID:19701182
Molecular FunctionGO:0003964RNA-directed DNA polymerase activityTERTIDAHumanPMID:21937513
Molecular FunctionGO:0003968RNA-directed RNA polymerase activityTERTIDAHumanPMID:19701182
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:12135483
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:16043710
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:21531765
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:16507993
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:17940095
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:18082603
Molecular FunctionGO:0003720telomerase activityTERTIDAHumanPMID:9443919
Molecular FunctionGO:0003720telomerase activityTertIDAMouseMGI:MGI:3027215|PMID:14701760
Molecular FunctionGO:0070034telomerase RNA bindingTERTIDAHumanPMID:11432839
Molecular FunctionGO:0070034telomerase RNA bindingTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:16507993
Molecular FunctionGO:0070034telomerase RNA bindingTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:17940095
Molecular FunctionGO:0070034telomerase RNA bindingTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:18082603
Molecular FunctionGO:0070034telomerase RNA bindingTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:19701182
Molecular FunctionGO:0070034telomerase RNA bindingTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:20351177
Molecular FunctionGO:0070034telomerase RNA bindingTertIPIRNAcentral:URS00004A7003_9606MouseMGI:MGI:5700305|PMID:16507993
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityTERTIDAHumanPMID:15632080
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityTERTIDAHumanPMID:17940095
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityTERTIMPHumanPMID:11313459
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityTERTIDAHumanPMID:19701182
Molecular FunctionGO:0003721telomerase RNA reverse transcriptase activityTERTIDAHumanPMID:9398860
Molecular FunctionGO:0001223transcription coactivator bindingTERTIPIUniProtKB:P51532HumanPMID:19571879
Molecular FunctionGO:0001223transcription coactivator bindingTertIPIUniProtKB:Q3TKT4MouseMGI:MGI:3850567|PMID:19571879
Molecular FunctionGO:0000049tRNA bindingTERTIDAHumanPMID:21937513
Cellular ComponentGO:0005737cytoplasmTertIDAMouseMGI:MGI:5616266|PMID:24970747
Cellular ComponentGO:0005737cytoplasmTertIDARatRGD:2291978|PMID:11485973
Cellular ComponentGO:0042645mitochondrial nucleoidTERTIDAHumanPMID:21937513
Cellular ComponentGO:0005739mitochondrionTertIDAMouseMGI:MGI:5607222|PMID:21937513
Cellular ComponentGO:0005739mitochondrionTertIDARatRGD:10047279|PMID:21937513
Cellular ComponentGO:0005739mitochondrionTertIDARatPMID:21937513
Cellular ComponentGO:0000784nuclear chromosome, telomeric regionTERTIDAHumanPMID:25589350
Cellular ComponentGO:0005730nucleolusTERTIDAHumanPMID:22226966
Cellular ComponentGO:0005654nucleoplasmTERTIDAHumanPMID:19567472
Cellular ComponentGO:0005634nucleusTERTIDAHumanPMID:21829167
Cellular ComponentGO:0005634nucleusTERTIDAHumanPMID:24415760
Cellular ComponentGO:0005634nucleusTertIDARatRGD:2291978|PMID:11485973
Cellular ComponentGO:0005886plasma membraneTertIDAMouseMGI:MGI:5616266|PMID:24970747
Cellular ComponentGO:0016605PML bodyTERTIDAHumanPMID:19567472
Cellular ComponentGO:0031379RNA-directed RNA polymerase complexTERTIPIRNAcentral:URS000075C8FA_9606HumanPMID:19701182
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIMPHumanPMID:11313459
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIDAHumanPMID:16507993
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIDAHumanPMID:17940095
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIDAHumanPMID:18082603
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:19701182
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIDAHumanPMID:9398860
Cellular ComponentGO:0000333telomerase catalytic core complexTERTIDAHumanPMID:9443919
Cellular ComponentGO:0000333telomerase catalytic core complexTertIMPMouseMGI:MGI:3588604|PMID:16037417
Cellular ComponentGO:0005697telomerase holoenzyme complexTERTIDAHumanPMID:12135483
Cellular ComponentGO:0005697telomerase holoenzyme complexTERTIDAHumanPMID:18082603
Cellular ComponentGO:0005697telomerase holoenzyme complexTERTIPIRNAcentral:URS00004A7003_9606HumanPMID:19701182
Cellular ComponentGO:1990572TERT-RMRP complexTERTIDAHumanPMID:19701182
Biological ProcessGO:0071456cellular response to hypoxiaTERTIMPHumanPMID:11313459
Biological ProcessGO:0071897DNA biosynthetic processTERTIDAHumanPMID:19701182
Biological ProcessGO:0071897DNA biosynthetic processTERTIDAHumanPMID:9398860
Biological ProcessGO:0022616DNA strand elongationTERTIDAHumanPMID:16043710
Biological ProcessGO:0070200establishment of protein localization to telomereTERTIDAHumanPMID:25589350
Biological ProcessGO:0007005mitochondrion organizationTERTIDAHumanPMID:21937513
Biological ProcessGO:0043066negative regulation of apoptotic processTertIMPRatRGD:11038674|PMID:20138964
Biological ProcessGO:2000773negative regulation of cellular senescenceTERTIMPHumanPMID:11313459
Biological ProcessGO:2000773negative regulation of cellular senescenceTERTIDAHumanPMID:11927518
Biological ProcessGO:2000352negative regulation of endothelial cell apoptotic processTertIDARatRGD:11038770|PMID:23013219
Biological ProcessGO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligandTERTIMPHumanPMID:10449030
Biological ProcessGO:0010629negative regulation of gene expressionTERTIDAHumanPMID:11927518
Biological ProcessGO:0060253negative regulation of glial cell proliferationTertIDARatRGD:11038672|PMID:21940960
Biological ProcessGO:0043524negative regulation of neuron apoptotic processTertIMPRatRGD:11038670|PMID:23968592
Biological ProcessGO:1903704negative regulation of production of siRNA involved in RNA interferenceTERTIDAHumanPMID:19701182
Biological ProcessGO:0045766positive regulation of angiogenesisTertIDARatRGD:11038770|PMID:23013219
Biological ProcessGO:1900087positive regulation of G1/S transition of mitotic cell cycleTertIMPRatRGD:11038675|PMID:24376652
Biological ProcessGO:0046326positive regulation of glucose importTertIMPMouseMGI:MGI:5616266|PMID:24970747
Biological ProcessGO:0042635positive regulation of hair cycleTertIMPMouseMGI:MGI:3588604|PMID:16037417
Biological ProcessGO:0042635positive regulation of hair cycleTertIMPMouseMGI:MGI:3589051|PMID:16107853
Biological ProcessGO:0051000positive regulation of nitric-oxide synthase activityTERTIDAHumanPMID:11927518
Biological ProcessGO:1902895positive regulation of pri-miRNA transcription from RNA polymerase II promoterTERTIMPHumanPMID:25569094
Biological ProcessGO:0032092positive regulation of protein bindingTERTIDAHumanPMID:24415760
Biological ProcessGO:1904751positive regulation of protein localization to nucleolusTERTIDAHumanPMID:24415760
Biological ProcessGO:2000648positive regulation of stem cell proliferationTertIMPMouseMGI:MGI:3589051|PMID:16107853
Biological ProcessGO:2000648positive regulation of stem cell proliferationTertIMPMouseMGI:MGI:3588604|PMID:16037417
Biological ProcessGO:1903620positive regulation of transdifferentiationTertIMPRatRGD:11038675|PMID:24376652
Biological ProcessGO:1904754positive regulation of vascular associated smooth muscle cell migrationTertIMPRatRGD:11038675|PMID:24376652
Biological ProcessGO:1904707positive regulation of vascular smooth muscle cell proliferationTertIMPRatRGD:11038675|PMID:24376652
Biological ProcessGO:0030177positive regulation of Wnt signaling pathwayTERTIGIUniProtKB:O70372HumanPMID:19571879
Biological ProcessGO:0030177positive regulation of Wnt signaling pathwayTertIGIUniProtKB:O88566MouseMGI:MGI:3850567|PMID:19571879
Biological ProcessGO:0030422production of siRNA involved in RNA interferenceTERTIDAHumanPMID:19701182
Biological ProcessGO:0031647regulation of protein stabilityTERTIDAHumanPMID:24415760
Biological ProcessGO:0031647regulation of protein stabilityTERTIDAHumanPMID:26194824
Biological ProcessGO:0031647regulation of protein stabilityTERTIMPHumanPMID:26194824
Biological ProcessGO:0090399replicative senescenceTERTIMPHumanPMID:9454332
Biological ProcessGO:0032774RNA biosynthetic processTERTIDAHumanPMID:19701182
Biological ProcessGO:0006278RNA-dependent DNA replicationTERTIDAHumanPMID:9398860
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIDAHumanPMID:16043710
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIDAHumanPMID:17940095
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIDAHumanPMID:19701182
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIDAHumanPMID:21531765
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIDAHumanPMID:9443919
Biological ProcessGO:0007004telomere maintenance via telomeraseTERTIMPHumanPMID:9454332
Biological ProcessGO:0001172transcription, RNA-templatedTERTIDAHumanPMID:19701182

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory