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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
2433

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:2433

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:2433
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0042802identical protein bindingTGFB3IDAHumanPMID:18243111
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:Q14766HumanPMID:10930463
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:Q9NS15HumanPMID:10930463
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173-1HumanPMID:11157754
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173-2HumanPMID:11157754
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173HumanPMID:11850637
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P17813HumanPMID:1326540
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:Q99MQ4HumanPMID:17827158
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P36897HumanPMID:18243111
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173HumanPMID:18243111
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173HumanPMID:21423151
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P37173HumanPMID:7852346
Molecular FunctionGO:0005515protein bindingTGFB3IPIUniProtKB:P17813HumanPMID:9872992
Molecular FunctionGO:0046982protein heterodimerization activityTgfb3IDARatRGD:2302086|PMID:18406405
Molecular FunctionGO:0050431transforming growth factor beta bindingTGFB3IDAHumanPMID:18243111
Molecular FunctionGO:0034713type I transforming growth factor beta receptor bindingTGFB3IDAHumanPMID:18243111
Molecular FunctionGO:0005114type II transforming growth factor beta receptor bindingTGFB3IDAHumanPMID:11157754
Molecular FunctionGO:0005114type II transforming growth factor beta receptor bindingTGFB3IPIUniProtKB:P37173HumanPMID:1333888
Molecular FunctionGO:0005114type II transforming growth factor beta receptor bindingTGFB3IDAHumanPMID:18243111
Cellular ComponentGO:0009986cell surfaceTgfb3IDARatRGD:2302094|PMID:16479080
Cellular ComponentGO:0005737cytoplasmTgfb3IDARatRGD:1625705|PMID:9281452
Cellular ComponentGO:0031012extracellular matrixTGFB3IDAHumanPMID:18049952
Cellular ComponentGO:0031012extracellular matrixTgfb3IDAMouseMGI:MGI:1934551|PMID:10521784
Cellular ComponentGO:0005615extracellular spaceTgfb3IDARatRGD:1625706|PMID:16891311
Cellular ComponentGO:0043025neuronal cell bodyTgfb3IDARatRGD:1601584|PMID:15214860
Cellular ComponentGO:0005634nucleusTgfb3IDARatRGD:1625705|PMID:9281452
Cellular ComponentGO:0030141secretory granuleTgfb3IDARatRGD:1601584|PMID:15214860
Cellular ComponentGO:0030315T-tubuleTgfb3IDARatRGD:1625705|PMID:9281452
Biological ProcessGO:0000187activation of MAPK activityTgfb3IDARatRGD:1579859|PMID:14605008
Biological ProcessGO:0045216cell-cell junction organizationTGFB3IDAHumanPMID:18505915
Biological ProcessGO:0071363cellular response to growth factor stimulusTgfb3IDAMouseMGI:MGI:69105|PMID:7848824
Biological ProcessGO:0070483detection of hypoxiaTGFB3IDAHumanPMID:18156205
Biological ProcessGO:0009790embryo developmentTgfb3IMPMGI:MGI:2158731MouseMGI:MGI:2686855|PMID:14729481
Biological ProcessGO:0048702embryonic neurocranium morphogenesisTgfb3IDARatRGD:1579866|PMID:11002343
Biological ProcessGO:0060325face morphogenesisTGFB3IMPHumanPMID:12651933
Biological ProcessGO:0001701in utero embryonic developmentTgfb3IMPMGI:MGI:2158731MouseMGI:MGI:2686855|PMID:14729481
Biological ProcessGO:0048286lung alveolus developmentTgfb3IMPMouseMGI:MGI:77427|PMID:7493022
Biological ProcessGO:0030879mammary gland developmentTgfb3IDAMouseMGI:MGI:50512|PMID:1821856
Biological ProcessGO:0008285negative regulation of cell proliferationTgfb3IDAMouseMGI:MGI:2667731|PMID:12815624
Biological ProcessGO:0008285negative regulation of cell proliferationTgfb3IDARatRGD:1579866|PMID:11002343
Biological ProcessGO:0008156negative regulation of DNA replicationTGFB3IMPHumanPMID:11158066
Biological ProcessGO:0010936negative regulation of macrophage cytokine productionTGFB3IDAHumanPMID:20875417
Biological ProcessGO:0043524negative regulation of neuron apoptotic processTgfb3IMPMGI:MGI:1857259MouseMGI:MGI:3696537|PMID:17159989
Biological ProcessGO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayTgfb3IDARatRGD:730235|PMID:12071374
Biological ProcessGO:0009887organ morphogenesisTgfb3IMPMGI:MGI:1857259MouseMGI:MGI:2686862|PMID:14697364
Biological ProcessGO:0060021palate developmentTgfb3IMPMouseMGI:MGI:77427|PMID:7493022
Biological ProcessGO:0060021palate developmentTgfb3IMPMouseMGI:MGI:2683382|PMID:14691138
Biological ProcessGO:0043065positive regulation of apoptotic processTgfb3IMPMGI:MGI:2158731MouseMGI:MGI:3701721|PMID:16806156
Biological ProcessGO:0043065positive regulation of apoptotic processTgfb3IDARatRGD:1579866|PMID:11002343
Biological ProcessGO:0043065positive regulation of apoptotic processTgfb3IMPRatRGD:2302092|PMID:16532270
Biological ProcessGO:0032967positive regulation of collagen biosynthetic processTGFB3IMPHumanPMID:11158066
Biological ProcessGO:0045740positive regulation of DNA replicationTGFB3IMPHumanPMID:11158066
Biological ProcessGO:0010718positive regulation of epithelial to mesenchymal transitionTGFB3IDAHumanPMID:18505915
Biological ProcessGO:0010718positive regulation of epithelial to mesenchymal transitionTgfb3IMPMouseMGI:MGI:2683382|PMID:14691138
Biological ProcessGO:0051491positive regulation of filopodium assemblyTgfb3IMPMGI:MGI:2158731MouseMGI:MGI:3701721|PMID:16806156
Biological ProcessGO:0010862positive regulation of pathway-restricted SMAD protein phosphorylationTgfb3IMPMouseMGI:MGI:2683382|PMID:14691138
Biological ProcessGO:0050714positive regulation of protein secretionTGFB3IDAHumanPMID:18505915
Biological ProcessGO:0060391positive regulation of SMAD protein import into nucleusTgfb3IMPMouseMGI:MGI:2683382|PMID:14691138
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterTgfb3IGIMGI:MGI:1314872|MGI:MGI:894293|MGI:MGI:108051|MGI:MGI:1201674MouseMGI:MGI:3696537|PMID:17159989
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTGFB3IDAHumanPMID:18156205
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedTgfb3IMPMouseMGI:MGI:2683382|PMID:14691138
Biological ProcessGO:0043627response to estrogenTgfb3IDARatRGD:1579859|PMID:14605008
Biological ProcessGO:0001666response to hypoxiaTGFB3IDAHumanPMID:18156205
Biological ProcessGO:0032570response to progesteroneTGFB3IDAHumanPMID:18039789
Biological ProcessGO:0007184SMAD protein import into nucleusTgfb3IDARatRGD:625677|PMID:12239085
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayTGFB3IDAHumanPMID:11157754

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory