Comparative GO Graph (mouse, human, rat)

• Source: HomoloGene (Release 68, May 6, 2014)
• Class ID: 22951

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

• This class contains
  • Human genes MTMR2
  • Mouse genes Mtmr2
  • Rat genes Mtmr2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD.
• Only experimental annotations are displayed: EXP, IDA, IGI, IMP, IPI. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:22951

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0052866	phosphatidylinositol phosphate phosphatase activity	Mtmr2	IMP	MGI:MGI:3513454	Mouse	MGI:MGI:5296993|PMID:22028665
Molecular Function	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	MTMR2	IDA		Human	PMID:12668758
Molecular Function	GO:0004438	phosphatidylinositol-3-phosphatase activity	MTMR2	IDA		Human	PMID:12668758
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:P07196	Human	PMID:12837694
Molecular Function	GO:0005515	protein binding	MTMR2	IPI	UniProtKB:Q86WG5	Human	PMID:15998640
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:P31016	Rat	RGD:8553482|PMID:20410104
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:Q62936	Rat	RGD:8553482|PMID:20410104
Molecular Function	GO:0005515	protein binding	Mtmr2	IPI	UniProtKB:Q63622	Rat	RGD:8553482|PMID:20410104
Molecular Function	GO:0042803	protein homodimerization activity	Mtmr2	IPI	UniProtKB:Q9Z2D1	Mouse	MGI:MGI:3619505|PMID:16399794
Cellular Component	GO:0030424	axon	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0005737	cytoplasm	MTMR2	IDA		Human	PMID:12837694
Cellular Component	GO:0005737	cytoplasm	Mtmr2	IDA		Mouse	MGI:MGI:2668305|PMID:12837694
Cellular Component	GO:0005737	cytoplasm	Mtmr2	IDA		Mouse	MGI:MGI:3619505|PMID:16399794
Cellular Component	GO:0005829	cytosol	MTMR2	IDA		Human	PMID:12668758
Cellular Component	GO:0005829	cytosol	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0030425	dendrite	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0043197	dendritic spine	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0070062	extracellular exosome	MTMR2	IDA		Human	PMID:18570454
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	MTMR2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	MTMR2	IDA		Human	PMID:12837694
Cellular Component	GO:0014069	postsynaptic density	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0097060	synaptic membrane	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0008021	synaptic vesicle	Mtmr2	IDA		Rat	RGD:8553482|PMID:20410104
Cellular Component	GO:0005774	vacuolar membrane	Mtmr2	IDA		Mouse	MGI:MGI:3619505|PMID:16399794
Biological Process	GO:0097062	dendritic spine maintenance	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0016311	dephosphorylation	Mtmr2	IDA		Mouse	MGI:MGI:3619505|PMID:16399794
Biological Process	GO:0046855	inositol phosphate dephosphorylation	Mtmr2	IDA		Mouse	MGI:MGI:3619505|PMID:16399794
Biological Process	GO:0032288	myelin assembly	Mtmr2	IGI	MGI:MGI:1335106	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:0032288	myelin assembly	Mtmr2	IGI	MGI:MGI:2143585	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:0032288	myelin assembly	Mtmr2	IMP	MGI:MGI:3513454	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:0045806	negative regulation of endocytosis	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0031642	negative regulation of myelination	Mtmr2	IMP	MGI:MGI:3513454	Mouse	MGI:MGI:4352761|PMID:19587293
Biological Process	GO:0031642	negative regulation of myelination	Mtmr2	IGI	MGI:MGI:2143585	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:2000645	negative regulation of receptor catabolic process	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0002091	negative regulation of receptor internalization	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0048666	neuron development	Mtmr2	IGI	MGI:MGI:2143585	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	MTMR2	IDA		Human	PMID:12668758
Biological Process	GO:0046856	phosphatidylinositol dephosphorylation	Mtmr2	IDA		Mouse	MGI:MGI:3619505|PMID:16399794
Biological Process	GO:0046488	phosphatidylinositol metabolic process	Mtmr2	IMP	MGI:MGI:3513454	Mouse	MGI:MGI:5296993|PMID:22028665
Biological Process	GO:2000643	positive regulation of early endosome to late endosome transport	Mtmr2	IMP		Rat	RGD:8553482|PMID:20410104
Biological Process	GO:0051262	protein tetramerization	Mtmr2	IPI	UniProtKB:Q91VH0	Mouse	MGI:MGI:3619505|PMID:16399794

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction