About   Help   FAQ
Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
22586

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:22586

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:22586
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005509calcium ion bindingIHHIDAHumanPMID:21537345
Molecular FunctionGO:0005113patched bindingIHHIPIUniProtKB:Q61115HumanPMID:21537345
Molecular FunctionGO:0005113patched bindingIhhIPIUniProtKB:Q13635|UniProtKB:Q9Y6C5MouseMGI:MGI:1313055|PMID:9811851
Molecular FunctionGO:0005515protein bindingIhhIPIUniProtKB:Q9WU59MouseMGI:MGI:1333378|PMID:10050855
Cellular ComponentGO:0031012extracellular matrixIhhIDAMouseMGI:MGI:2149274|PMID:11476578
Cellular ComponentGO:0005886plasma membraneIHHIDAHumanPMID:21537345
Biological ProcessGO:0045453bone resorptionIhhIDAMouseMGI:MGI:1335697|PMID:10208865
Biological ProcessGO:0043010camera-type eye developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0060220camera-type eye photoreceptor cell fate commitmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0051216cartilage developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3695832|PMID:17191253
Biological ProcessGO:0030154cell differentiationIhhIDAMouseMGI:MGI:3583389|PMID:15951842
Biological ProcessGO:0001708cell fate specificationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0048469cell maturationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3511731|PMID:15576404
Biological ProcessGO:0035988chondrocyte proliferationIhhIMPMGI:MGI:1934258MouseMGI:MGI:4999722|PMID:16935278
Biological ProcessGO:0009790embryo developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3766861|PMID:17881493
Biological ProcessGO:0048596embryonic camera-type eye morphogenesisIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0048557embryonic digestive tract morphogenesisIhhIMPMGI:MGI:1934258MouseMGI:MGI:1858523|PMID:10821773
Biological ProcessGO:0009880embryonic pattern specificationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0072498embryonic skeletal joint developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3695832|PMID:17191253
Biological ProcessGO:0003382epithelial cell morphogenesisIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0090136epithelial cell-cell adhesionIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0060323head morphogenesisIhhIMPMGI:MGI:1934258MouseMGI:MGI:4999722|PMID:16935278
Biological ProcessGO:0001947heart loopingIhhIMPMouseMGI:MGI:5142377|PMID:11517919
Biological ProcessGO:0001701in utero embryonic developmentIhhIMPMouseMGI:MGI:3766861|PMID:17881493
Biological ProcessGO:0001763morphogenesis of a branching structureIhhIMPMGI:MGI:1934258MouseMGI:MGI:1926239|PMID:11044404
Biological ProcessGO:0035264multicellular organism growthIhhIMPMGI:MGI:1934258MouseMGI:MGI:1858523|PMID:10821773
Biological ProcessGO:0046639negative regulation of alpha-beta T cell differentiationIhhIMPMouseMGI:MGI:3836494|PMID:19109233
Biological ProcessGO:0043066negative regulation of apoptotic processIhhIMPRatRGD:1600038|PMID:16488438
Biological ProcessGO:0045596negative regulation of cell differentiationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3608261|PMID:16284117
Biological ProcessGO:0048074negative regulation of eye pigmentationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807630|PMID:17464332
Biological ProcessGO:0033088negative regulation of immature T cell proliferation in thymusIhhIMPMouseMGI:MGI:3836494|PMID:19109233
Biological ProcessGO:0009968negative regulation of signal transductionIhhIMPRatRGD:1299259|PMID:12082161
Biological ProcessGO:0033085negative regulation of T cell differentiation in thymusIhhIMPMouseMGI:MGI:3836494|PMID:19109233
Biological ProcessGO:0048666neuron developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:1858523|PMID:10821773
Biological ProcessGO:0001503ossificationIhhIMPMGI:MGI:1934258MouseMGI:MGI:2154465|PMID:11748145
Biological ProcessGO:0001649osteoblast differentiationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3036410|PMID:14973297
Biological ProcessGO:0031016pancreas developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:1858523|PMID:10821773
Biological ProcessGO:0031016pancreas developmentIhhIGIMGI:MGI:98297MouseMGI:MGI:1926239|PMID:11044404
Biological ProcessGO:0007389pattern specification processIhhIMPMGI:MGI:1857644MouseMGI:MGI:1277795|PMID:9671585
Biological ProcessGO:0001569patterning of blood vesselsIhhIMPMGI:MGI:1934258MouseMGI:MGI:3574706|PMID:15689378
Biological ProcessGO:0046638positive regulation of alpha-beta T cell differentiationIhhIMPMouseMGI:MGI:3836494|PMID:19109233
Biological ProcessGO:0008284positive regulation of cell proliferationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3608261|PMID:16284117
Biological ProcessGO:0008284positive regulation of cell proliferationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3695832|PMID:17191253
Biological ProcessGO:0008284positive regulation of cell proliferationIhhIGIMGI:MGI:95729MouseMGI:MGI:3695832|PMID:17191253
Biological ProcessGO:0008284positive regulation of cell proliferationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0032332positive regulation of chondrocyte differentiationIhhIMPRatRGD:1299259|PMID:12082161
Biological ProcessGO:0032967positive regulation of collagen biosynthetic processIhhIDAMouseMGI:MGI:1335697|PMID:10208865
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIhhIMPRatRGD:1600038|PMID:16488438
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0045880positive regulation of smoothened signaling pathwayIhhIMPMouseMGI:MGI:5142377|PMID:11517919
Biological ProcessGO:0033089positive regulation of T cell differentiation in thymusIhhIMPMouseMGI:MGI:3836494|PMID:19109233
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIhhIGIMGI:MGI:98297MouseMGI:MGI:3766861|PMID:17881493
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIhhIMPRatRGD:1299259|PMID:12082161
Biological ProcessGO:0006029proteoglycan metabolic processIhhIGIMGI:MGI:88177|MGI:MGI:88177MouseMGI:MGI:4999722|PMID:16935278
Biological ProcessGO:0045595regulation of cell differentiationIhhIMPRatRGD:1299259|PMID:12082161
Biological ProcessGO:0040008regulation of growthIhhIGIMGI:MGI:104903MouseMGI:MGI:4430672|PMID:19590577
Biological ProcessGO:0003406retinal pigment epithelium developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3807419|PMID:18582859
Biological ProcessGO:0001501skeletal system developmentIHHIMPHumanPMID:21537345
Biological ProcessGO:0001501skeletal system developmentIhhIMPMGI:MGI:3609381|MGI:MGI:2176264MouseMGI:MGI:3608181|PMID:16278811
Biological ProcessGO:0048745smooth muscle tissue developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:1858523|PMID:10821773
Biological ProcessGO:0007224smoothened signaling pathwayIHHIDAHumanPMID:21537345
Biological ProcessGO:0007224smoothened signaling pathwayIhhIGIMGI:MGI:104903MouseMGI:MGI:4430672|PMID:19590577
Biological ProcessGO:0007224smoothened signaling pathwayIhhIMPRatRGD:1299259|PMID:12082161
Biological ProcessGO:0061053somite developmentIhhIMPMouseMGI:MGI:5142377|PMID:11517919
Biological ProcessGO:0001944vasculature developmentIhhIMPMGI:MGI:1934258MouseMGI:MGI:3766861|PMID:17881493
Biological ProcessGO:0030704vitelline membrane formationIhhIMPMGI:MGI:1934258MouseMGI:MGI:3766861|PMID:17881493

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/19/2014
MGI 5.19
The Jackson Laboratory