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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
2241

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:2241

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:2241
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0031727CCR2 chemokine receptor bindingCcl2IPIUniProtKB:P51683MouseMGI:MGI:80507|PMID:8662823
Molecular FunctionGO:0031727CCR2 chemokine receptor bindingCcl2IMPRatRGD:1582321|PMID:16196033
Molecular FunctionGO:0031727CCR2 chemokine receptor bindingCcl2IMPRatRGD:2303073|PMID:18584881
Molecular FunctionGO:0008009chemokine activityCCL13IDAHumanPMID:10072545
Molecular FunctionGO:0008009chemokine activityCcl2IDARatRGD:2303089|PMID:12953273
Molecular FunctionGO:0008009chemokine activityCcl2IDARatRGD:2303093|PMID:16127145
Molecular FunctionGO:0008009chemokine activityCcl2IDARatRGD:2303114|PMID:11104723
Molecular FunctionGO:0005125cytokine activityCcl2IDAMouseMGI:MGI:5468848|PMID:23395675
Molecular FunctionGO:0001664G-protein coupled receptor bindingCcl2IDAMouseMGI:MGI:79768|PMID:8631787
Molecular FunctionGO:0001664G-protein coupled receptor bindingCcl2IDAMouseMGI:MGI:1099921|PMID:9366570
Molecular FunctionGO:0008201heparin bindingCcl2IPICHEBI:28304RatRGD:2303093|PMID:16127145
Molecular FunctionGO:0005515protein bindingCcl2IPIUniProtKB:P51675MouseMGI:MGI:79768|PMID:8631787
Cellular ComponentGO:0043679axon terminusCcl2IDARatRGD:2307005|PMID:19059387
Cellular ComponentGO:0044299C-fiberCcl2IDARatRGD:4890034|PMID:18076762
Cellular ComponentGO:0005737cytoplasmCcl2IDARatRGD:1358455|PMID:14638441
Cellular ComponentGO:0030425dendriteCcl2IDARatRGD:8549734|PMID:16025454
Cellular ComponentGO:0030139endocytic vesicleCcl2IDARatRGD:8549739|PMID:12080327
Cellular ComponentGO:0005615extracellular spaceCcl2IDAMouseMGI:MGI:5468848|PMID:23395675
Cellular ComponentGO:0005615extracellular spaceCcl2IDAMouseMGI:MGI:3839525|PMID:19139201
Cellular ComponentGO:0005615extracellular spaceCcl2IDAMouseMGI:MGI:5562512|PMID:23892723
Cellular ComponentGO:0005615extracellular spaceCcl2IDAMouseMGI:MGI:5776677|PMID:22960654
Cellular ComponentGO:0005615extracellular spaceCcl2IDAMouseMGI:MGI:5640941|PMID:24006456
Cellular ComponentGO:0005615extracellular spaceCcl2IDARatRGD:2307004|PMID:19060786
Cellular ComponentGO:0043025neuronal cell bodyCcl2IDARatRGD:1625372|PMID:15978006
Cellular ComponentGO:0043204perikaryonCcl2IDARatRGD:8549734|PMID:16025454
Cellular ComponentGO:0048471perinuclear region of cytoplasmCcl2IDARatRGD:8548859|PMID:14512159
Cellular ComponentGO:0005791rough endoplasmic reticulumCcl2IDARatRGD:8549739|PMID:12080327
Cellular ComponentGO:0045202synapseCcl2IDARatRGD:8548887|PMID:23010641
Biological ProcessGO:0006874cellular calcium ion homeostasisCcl2IDARatRGD:1625372|PMID:15978006
Biological ProcessGO:0071346cellular response to interferon-gammaCcl2IDAMouseMGI:MGI:3699670|PMID:14662900
Biological ProcessGO:0071347cellular response to interleukin-1Ccl2IDAMouseMGI:MGI:3699670|PMID:14662900
Biological ProcessGO:0071222cellular response to lipopolysaccharideCcl2IDAMouseMGI:MGI:3699670|PMID:14662900
Biological ProcessGO:0071356cellular response to tumor necrosis factorCcl2IDAMouseMGI:MGI:3699670|PMID:14662900
Biological ProcessGO:0070098chemokine-mediated signaling pathwayCcl2IMPRatRGD:2303073|PMID:18584881
Biological ProcessGO:0019221cytokine-mediated signaling pathwayCcl2IMPRatRGD:1625370|PMID:16174730
Biological ProcessGO:0007010cytoskeleton organizationCCL13IDAHumanPMID:10072545
Biological ProcessGO:0048245eosinophil chemotaxisCCL13IDAHumanPMID:10072545
Biological ProcessGO:0008347glial cell migrationCcl2IMPRatRGD:8548887|PMID:23010641
Biological ProcessGO:0035684helper T cell extravasationCcl2IDAMouseMGI:MGI:3812298|PMID:18586982
Biological ProcessGO:0002523leukocyte migration involved in inflammatory responseCcl2IMPRatRGD:8549532|PMID:8774140
Biological ProcessGO:0048247lymphocyte chemotaxisCcl2IDARatRGD:2303114|PMID:11104723
Biological ProcessGO:0048246macrophage chemotaxisCcl2IDARatRGD:2303093|PMID:16127145
Biological ProcessGO:0016525negative regulation of angiogenesisCcl2IMPMouseMGI:MGI:3840068|PMID:14566334
Biological ProcessGO:0030593neutrophil chemotaxisCcl2IMPRatRGD:2303093|PMID:16127145
Biological ProcessGO:2000427positive regulation of apoptotic cell clearanceCcl2IDAMouseMGI:MGI:4943793|PMID:20691665
Biological ProcessGO:0045785positive regulation of cell adhesionCcl2IDARatRGD:8549560|PMID:8103296
Biological ProcessGO:0022409positive regulation of cell-cell adhesionCcl2IDARatRGD:8549768|PMID:10225970
Biological ProcessGO:0002693positive regulation of cellular extravasationCcl2IDARatRGD:8549768|PMID:10225970
Biological ProcessGO:0032967positive regulation of collagen biosynthetic processCcl2IDARatRGD:8549527|PMID:8663511
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationCcl2IMPRatRGD:1580560|PMID:14693680
Biological ProcessGO:0090265positive regulation of immune complex clearance by monocytes and macrophagesCcl2IMPMouseMGI:MGI:3840068|PMID:14566334
Biological ProcessGO:0001912positive regulation of leukocyte mediated cytotoxicityCcl2IMPRatRGD:8549560|PMID:8103296
Biological ProcessGO:0002687positive regulation of leukocyte migrationCcl2IMPRatRGD:8548859|PMID:14512159
Biological ProcessGO:0002687positive regulation of leukocyte migrationCcl2IDARatRGD:8549570|PMID:7943176
Biological ProcessGO:0010759positive regulation of macrophage chemotaxisCcl2IDAMouseMGI:MGI:3840068|PMID:14566334
Biological ProcessGO:0010759positive regulation of macrophage chemotaxisCcl2IDARatRGD:8549586|PMID:9430491
Biological ProcessGO:0090026positive regulation of monocyte chemotaxisCcl2IDAMouseMGI:MGI:5634870|PMID:25651887
Biological ProcessGO:0090026positive regulation of monocyte chemotaxisCcl2IDARatRGD:8549558|PMID:1387671
Biological ProcessGO:0051770positive regulation of nitric-oxide synthase biosynthetic processCcl2IMPMouseMGI:MGI:4943659|PMID:19164781
Biological ProcessGO:0090314positive regulation of protein targeting to membraneCcl2IDARatRGD:9685053|PMID:22222817
Biological ProcessGO:0050806positive regulation of synaptic transmissionCcl2IDARatRGD:2303073|PMID:18584881
Biological ProcessGO:0050870positive regulation of T cell activationCcl2IMPMouseMGI:MGI:3699670|PMID:14662900
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionCcl2IMPRatRGD:8661667|PMID:24826069
Biological ProcessGO:0090303positive regulation of wound healingCcl2IMPRatRGD:11526146|PMID:12831234
Biological ProcessGO:0008360regulation of cell shapeCCL13IDAHumanPMID:10072545
Biological ProcessGO:0010574regulation of vascular endothelial growth factor productionCcl2IMPMouseMGI:MGI:3840068|PMID:14566334
Biological ProcessGO:0009408response to heatCcl2IDARatRGD:2307043|PMID:18419759
Biological ProcessGO:0009611response to woundingCcl2IDAMouseMGI:MGI:3844151|PMID:19404405
Biological ProcessGO:0007179transforming growth factor beta receptor signaling pathwayCcl2IMPRatRGD:1582324|PMID:14505427
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayCcl2IMPRatRGD:1580560|PMID:14693680

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory