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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
2162

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:2162

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:2162
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005525GTP bindingRap1aIDARatRGD:10003134|PMID:20339002
Molecular FunctionGO:0003924GTPase activityRap1aIDAMouseMGI:MGI:2450214|PMID:12473665
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q9Y4G8HumanPMID:10608844
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q9P212HumanPMID:11022048
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q9Y4G8HumanPMID:11359771
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q5EBH1HumanPMID:12845325
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q8WWW0-2HumanPMID:12845325
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:Q8WWW0-2HumanPMID:15569673
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:O00522HumanPMID:17916086
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:P04049HumanPMID:7791872
Molecular FunctionGO:0005515protein bindingRAP1AIPIUniProtKB:P04049HumanPMID:8756332
Molecular FunctionGO:0005515protein bindingRap1aIPIUniProtKB:P63321MouseMGI:MGI:3032880|PMID:14712229
Molecular FunctionGO:0005515protein bindingRap1aIPIUniProtKB:Q5EBH1MouseMGI:MGI:3803025|PMID:18596699
Molecular FunctionGO:0005515protein bindingRap1aIPIUniProtKB:Q8R5A3MouseMGI:MGI:3714085|PMID:17403904
Molecular FunctionGO:0005515protein bindingRap1aIPIRGD:1351009RatRGD:10003147|PMID:16436672
Molecular FunctionGO:0032403protein complex bindingRAP1AIDAHumanPMID:17916086
Molecular FunctionGO:0032403protein complex bindingRAP1AIDAHumanPMID:23209302
Molecular FunctionGO:0008565protein transporter activityRAP1AIDAHumanPMID:17916086
Molecular FunctionGO:0017034Rap guanyl-nucleotide exchange factor activityRap1aIMPRatRGD:8554481|PMID:17724123
Molecular FunctionGO:0017016Ras GTPase bindingRap1aIPIRefSeq:NP_997129MouseMGI:MGI:3583869|PMID:15894621
Cellular ComponentGO:0030054cell junctionRap1aIDAMouseMGI:MGI:4359570|PMID:19635461
Cellular ComponentGO:0005737cytoplasmRAP1AIDAHumanPMID:11359771
Cellular ComponentGO:0005737cytoplasmRAP1AIDAHumanPMID:23209302
Cellular ComponentGO:0005737cytoplasmRap1aIDAMouseMGI:MGI:5527508|PMID:22732430
Cellular ComponentGO:0005737cytoplasmRap1aIDARatRGD:8554481|PMID:17724123
Cellular ComponentGO:0005769early endosomeRap1aIDARatRGD:10040965|PMID:17822405
Cellular ComponentGO:0005769early endosomeRap1aIDARatRGD:8554481|PMID:17724123
Cellular ComponentGO:0070062extracellular exosomeRAP1AIDAHumanPMID:20458337
Cellular ComponentGO:0070062extracellular exosomeRAP1AIDAHumanPMID:23376485
Cellular ComponentGO:0032045guanyl-nucleotide exchange factor complexRap1aIDAMouseMGI:MGI:3583869|PMID:15894621
Cellular ComponentGO:0005770late endosomeRap1aIDARatRGD:8554481|PMID:17724123
Cellular ComponentGO:0043209myelin sheathRap1aIDAMouseMGI:MGI:3834050|PMID:17634366
Cellular ComponentGO:0043005neuron projectionRap1aIDAMouseMGI:MGI:5527508|PMID:22732430
Cellular ComponentGO:0048471perinuclear region of cytoplasmRAP1AIDAHumanPMID:11359771
Cellular ComponentGO:0048471perinuclear region of cytoplasmRap1aIDARatRGD:10040965|PMID:17822405
Cellular ComponentGO:0048471perinuclear region of cytoplasmRap1aIDARatRGD:8554481|PMID:17724123
Cellular ComponentGO:0045335phagocytic vesicleRap1aIDARatRGD:9835043|PMID:18832707
Cellular ComponentGO:0005886plasma membraneRap1aIDAMouseMGI:MGI:3714085|PMID:17403904
Biological ProcessGO:0071320cellular response to cAMPRAP1AIDAHumanPMID:21840392
Biological ProcessGO:0035690cellular response to drugRap1aIDARatRGD:10003157|PMID:10908723
Biological ProcessGO:1990090cellular response to nerve growth factor stimulusRap1aIDARatRGD:8554481|PMID:17724123
Biological ProcessGO:0071407cellular response to organic cyclic compoundRap1aIDARatRGD:10003157|PMID:10908723
Biological ProcessGO:0061028establishment of endothelial barrierRAP1AIMPHumanPMID:21840392
Biological ProcessGO:0032966negative regulation of collagen biosynthetic processRap1aIMPRatRGD:9850086|PMID:22012077
Biological ProcessGO:2000301negative regulation of synaptic vesicle exocytosisRap1aIGIMGI:MGI:894315MouseMGI:MGI:5490391|PMID:23616533
Biological ProcessGO:0038180nerve growth factor signaling pathwayRap1aIDARatRGD:8554481|PMID:17724123
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeRap1aIGIMGI:MGI:894315MouseMGI:MGI:5490391|PMID:23616533
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeRap1aIMPRatRGD:8554481|PMID:17724123
Biological ProcessGO:1905451positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosisRap1aIMPRatRGD:9835043|PMID:18832707
Biological ProcessGO:0046326positive regulation of glucose importRap1aIMPRatRGD:10040970|PMID:17450172
Biological ProcessGO:0043547positive regulation of GTPase activityRap1aIMPRatRGD:8554481|PMID:17724123
Biological ProcessGO:0010976positive regulation of neuron projection developmentRap1aIDAMouseMGI:MGI:5527508|PMID:22732430
Biological ProcessGO:0010976positive regulation of neuron projection developmentRap1aIMPRatRGD:8554481|PMID:17724123
Biological ProcessGO:0010976positive regulation of neuron projection developmentRap1aIMPRatRGD:9835044|PMID:20190816
Biological ProcessGO:0045860positive regulation of protein kinase activityRap1aIMPRatRGD:8554481|PMID:17724123
Biological ProcessGO:2001214positive regulation of vasculogenesisRap1aIMPMouseMGI:MGI:4359570|PMID:19635461
Biological ProcessGO:0015031protein transportRAP1AIDAHumanPMID:17916086
Biological ProcessGO:0032486Rap protein signal transductionRAP1AIMPHumanPMID:21840392
Biological ProcessGO:1901888regulation of cell junction assemblyRAP1AIMPHumanPMID:21840392
Biological ProcessGO:0097327response to antineoplastic agentRap1aIDARatRGD:10040965|PMID:17822405
Biological ProcessGO:0007264small GTPase mediated signal transductionRap1aIDAMouseMGI:MGI:2450214|PMID:12473665

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/17/2018
MGI 6.11
The Jackson Laboratory