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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
21040

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:21040

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:21040
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005178integrin bindingMmp14IPIRGD:2927RatRGD:2307395|PMID:19027888
Molecular FunctionGO:0070006metalloaminopeptidase activityMMP14IDAHumanPMID:24970228
Molecular FunctionGO:0004222metalloendopeptidase activityMmp14IDAMouseMGI:MGI:5013661|PMID:21572390
Molecular FunctionGO:0004222metalloendopeptidase activityMmp14IMPMouseMGI:MGI:5699659|PMID:24990232
Molecular FunctionGO:0016504peptidase activator activityMmp14IMPRatRGD:1582606|PMID:14668206
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:Q9BV57HumanPMID:14718544
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:P56945HumanPMID:18164686
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:Q9R064HumanPMID:20608975
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:P53667HumanPMID:21219645
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:Q61483HumanPMID:21572390
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:Q10589HumanPMID:22065321
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:P16035HumanPMID:24112707
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:P51884HumanPMID:25304424
Molecular FunctionGO:0005515protein bindingMMP14IPIUniProtKB:Q8N6L0HumanPMID:25416956
Cellular ComponentGO:0005737cytoplasmMMP14IDAHumanPMID:22065321
Cellular ComponentGO:0005737cytoplasmMmp14IDARatRGD:1582597|PMID:16740171
Cellular ComponentGO:0031410cytoplasmic vesicleMMP14IDAHumanPMID:24859005
Cellular ComponentGO:0005829cytosolMMP14IDAHumanGO_REF:0000052
Cellular ComponentGO:0005615extracellular spaceMMP14IMPHumanPMID:24784232
Cellular ComponentGO:0005925focal adhesionMMP14IDAHumanPMID:21423176
Cellular ComponentGO:0045111intermediate filament cytoskeletonMMP14IDAHumanGO_REF:0000052
Cellular ComponentGO:0044354macropinosomeMMP14IDAHumanPMID:24859005
Cellular ComponentGO:0005634nucleusMMP14IMPHumanPMID:24784232
Cellular ComponentGO:0005886plasma membraneMMP14IDAHumanPMID:15351710
Cellular ComponentGO:0005886plasma membraneMMP14IDAHumanPMID:24859005
Biological ProcessGO:0060348bone developmentMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0048754branching morphogenesis of an epithelial tubeMmp14IMPMGI:MGI:2386246MouseMGI:MGI:3527919|PMID:15572153
Biological ProcessGO:0016477cell migrationMmp14IMPMGI:MGI:2386246MouseMGI:MGI:3527919|PMID:15572153
Biological ProcessGO:0035988chondrocyte proliferationMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0030574collagen catabolic processMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0097094craniofacial suture morphogenesisMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0001958endochondral ossificationMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0030324lung developmentMmp14IMPMGI:MGI:2386246MouseMGI:MGI:3527919|PMID:15572153
Biological ProcessGO:0051895negative regulation of focal adhesion assemblyMmp14IDARatRGD:1582604|PMID:15044209
Biological ProcessGO:0045746negative regulation of Notch signaling pathwayMmp14IMPMouseMGI:MGI:5013661|PMID:21572390
Biological ProcessGO:0001503ossificationMmp14IGIMGI:MGI:1276107MouseMGI:MGI:3771253|PMID:18022611
Biological ProcessGO:0045579positive regulation of B cell differentiationMmp14IMPMouseMGI:MGI:5013661|PMID:21572390
Biological ProcessGO:0030307positive regulation of cell growthMMP14IDAHumanPMID:22065321
Biological ProcessGO:0030335positive regulation of cell migrationMMP14IDAHumanPMID:22065321
Biological ProcessGO:1905523positive regulation of macrophage migrationMmp14IMPMouseMGI:MGI:5699659|PMID:24990232
Biological ProcessGO:0010831positive regulation of myotube differentiationMmp14IMPMouseMGI:MGI:5013661|PMID:21572390
Biological ProcessGO:0006508proteolysisMMP14IDAHumanPMID:15863497
Biological ProcessGO:0006508proteolysisMMP14IDAHumanPMID:24970228
Biological ProcessGO:0009725response to hormoneMmp14IDARatRGD:1582606|PMID:14668206
Biological ProcessGO:0048771tissue remodelingMmp14IDARatRGD:1582597|PMID:16740171
Biological ProcessGO:0031638zymogen activationMmp14IMPMGI:MGI:2386246MouseMGI:MGI:3527919|PMID:15572153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/09/2018
MGI 6.12
The Jackson Laboratory