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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
20373

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:20373

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:20373
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003677DNA bindingFOXC1IDAHumanPMID:11179011
Molecular FunctionGO:0003677DNA bindingFOXC1IDAHumanPMID:15684392
Molecular FunctionGO:0003677DNA bindingFOXC1IDAHumanPMID:7957066
Molecular FunctionGO:0008301DNA binding, bendingFOXC1IDAHumanPMID:7957066
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:P21333HumanPMID:15684392
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:P40424HumanPMID:15684392
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:Q12857HumanPMID:15684392
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:Q99697-3HumanPMID:16449236
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:Q07021HumanPMID:18676636
Molecular FunctionGO:0005515protein bindingFOXC1IPIUniProtKB:Q9Q2G4HumanPMID:22190034
Molecular FunctionGO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityFoxc1IDAMouseMGI:MGI:3701373|PMID:16678147
Molecular FunctionGO:0043565sequence-specific DNA bindingFOXC1IDAHumanPMID:15277473
Molecular FunctionGO:0043565sequence-specific DNA bindingFOXC1IDAHumanPMID:7957066
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityFOXC1IDAHumanPMID:11179011
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityFOXC1IDAHumanPMID:15277473
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityFOXC1IDAHumanPMID:15684392
Molecular FunctionGO:0003700sequence-specific DNA binding transcription factor activityFoxc1IDAMouseMGI:MGI:3813419|PMID:18579532
Molecular FunctionGO:0008134transcription factor bindingFOXC1IPIUniProtKB:P40424-1HumanPMID:15684392
Molecular FunctionGO:0044212transcription regulatory region DNA bindingFoxc1IDAMouseMGI:MGI:3813419|PMID:18579532
Cellular ComponentGO:0005737cytoplasmFOXC1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005720nuclear heterochromatinFOXC1IDAHumanPMID:15684392
Cellular ComponentGO:0005634nucleusFOXC1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusFOXC1IDAHumanPMID:11179011
Cellular ComponentGO:0005634nucleusFOXC1IDAHumanPMID:11562355
Cellular ComponentGO:0005634nucleusFOXC1IDAHumanPMID:15277473
Cellular ComponentGO:0005634nucleusFOXC1IDAHumanPMID:16449236
Biological ProcessGO:0048844artery morphogenesisFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1345536|PMID:10479458
Biological ProcessGO:0001568blood vessel developmentFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0001974blood vessel remodelingFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:2150572|PMID:11562355
Biological ProcessGO:0001974blood vessel remodelingFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0007420brain developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53669|PMID:5500588
Biological ProcessGO:0007420brain developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53904|PMID:4784576
Biological ProcessGO:0007420brain developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1261705|PMID:9635428
Biological ProcessGO:0043010camera-type eye developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1340945|PMID:10395790
Biological ProcessGO:0043010camera-type eye developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1355577|PMID:10767326
Biological ProcessGO:0060038cardiac muscle cell proliferationFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0030199collagen fibril organizationFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1355577|PMID:10767326
Biological ProcessGO:0035050embryonic heart tube developmentFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0001654eye developmentFOXC1IDAHumanPMID:9792859
Biological ProcessGO:0001654eye developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1261705|PMID:9635428
Biological ProcessGO:0001654eye developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1335260|PMID:10072431
Biological ProcessGO:0008354germ cell migrationFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:3617053|PMID:16412416
Biological ProcessGO:0030203glycosaminoglycan metabolic processFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53846|PMID:4269479
Biological ProcessGO:0007507heart developmentFOXC1IDAHumanPMID:10474162
Biological ProcessGO:0007507heart developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1345536|PMID:10479458
Biological ProcessGO:0007507heart developmentFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0003007heart morphogenesisFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0001701in utero embryonic developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53909|PMID:4819561
Biological ProcessGO:0001822kidney developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53669|PMID:5500588
Biological ProcessGO:0001822kidney developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1353950|PMID:10704385
Biological ProcessGO:0032808lacrimal gland developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:3620414|PMID:16470615
Biological ProcessGO:0001945lymph vessel developmentFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0048762mesenchymal cell differentiationFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1261705|PMID:9635428
Biological ProcessGO:1902257negative regulation of apoptotic process involved in outflow tract morphogenesisFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0045930negative regulation of mitotic cell cycleFOXC1IDAHumanPMID:12408963
Biological ProcessGO:0014032neural crest cell developmentFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0007219Notch signaling pathwayFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:2150572|PMID:11562355
Biological ProcessGO:0042475odontogenesis of dentin-containing toothFOXC1IMPHumanPMID:12614756
Biological ProcessGO:0001503ossificationFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:2676506|PMID:14512019
Biological ProcessGO:0001541ovarian follicle developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:3617053|PMID:16412416
Biological ProcessGO:0048341paraxial mesoderm formationFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:2150572|PMID:11562355
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterFOXC1IDAHumanPMID:16449236
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterFoxc1IDAMouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterFoxc1IDAMouseMGI:MGI:3813419|PMID:18579532
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedFOXC1IDAHumanPMID:11237714
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedFOXC1IDAHumanPMID:15277473
Biological ProcessGO:0050880regulation of blood vessel sizeFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0046620regulation of organ growthFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542
Biological ProcessGO:0006355regulation of transcription, DNA-templatedFOXC1IDAHumanPMID:15684392
Biological ProcessGO:0001501skeletal system developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53669|PMID:5500588
Biological ProcessGO:0001501skeletal system developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:53904|PMID:4784576
Biological ProcessGO:0001501skeletal system developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:63127
Biological ProcessGO:0001501skeletal system developmentFoxc1IMPMGI:MGI:1857869MouseMGI:MGI:1261705|PMID:9635428
Biological ProcessGO:0001501skeletal system developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1335260|PMID:10072431
Biological ProcessGO:0001756somitogenesisFoxc1IGIUniProtKB:Q61850MouseMGI:MGI:2150572|PMID:11562355
Biological ProcessGO:0006366transcription from RNA polymerase II promoterFoxc1IDAMouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0001657ureteric bud developmentFoxc1IMPMGI:MGI:1856705MouseMGI:MGI:1353950|PMID:10704385
Biological ProcessGO:0048010vascular endothelial growth factor receptor signaling pathwayFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701373|PMID:16678147
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisFoxc1IGIMGI:MGI:1347481MouseMGI:MGI:3701735|PMID:16839542

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory