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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
20216

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:20216

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:20216
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0035240dopamine bindingDRD5IDAHumanPMID:1826762
Molecular FunctionGO:0004952dopamine neurotransmitter receptor activityDRD5IDAHumanPMID:1826762
Molecular FunctionGO:0004952dopamine neurotransmitter receptor activityDrd5IDARatRGD:728422|PMID:1831904
Molecular FunctionGO:0001588dopamine neurotransmitter receptor activity, coupled via GsDrd5IMPMouseMGI:MGI:3586401|PMID:13679419
Molecular FunctionGO:0001588dopamine neurotransmitter receptor activity, coupled via GsDrd5IDAMouseMGI:MGI:3689286|PMID:16962565
Molecular FunctionGO:0001588dopamine neurotransmitter receptor activity, coupled via GsDrd5IMPRatRGD:1600981|PMID:16855100
Molecular FunctionGO:0008144drug bindingDrd5IDARatRGD:1600981|PMID:16855100
Molecular FunctionGO:0001965G-protein alpha-subunit bindingDrd5IPIRGD:1310221RatRGD:730287|PMID:12623966
Molecular FunctionGO:0001965G-protein alpha-subunit bindingDrd5IPIRGD:71018RatRGD:730287|PMID:12623966
Molecular FunctionGO:0005515protein bindingDrd5IPIRGD:621859RatRGD:2311555|PMID:19465068
Cellular ComponentGO:0030424axonDrd5IDARatRGD:5686427|PMID:16175554
Cellular ComponentGO:0031526brush border membraneDrd5IDAMouseMGI:MGI:3526585|PMID:15598876
Cellular ComponentGO:0031526brush border membraneDrd5IDARatRGD:730287|PMID:12623966
Cellular ComponentGO:0060170ciliary membraneDRD5IDAHumanPMID:20531939
Cellular ComponentGO:0030425dendriteDrd5IDARatRGD:5686427|PMID:16175554
Cellular ComponentGO:0043197dendritic spineDrd5IDARatRGD:5686425|PMID:21749912
Cellular ComponentGO:0043025neuronal cell bodyDrd5IDARatRGD:5686425|PMID:21749912
Cellular ComponentGO:0097730non-motile ciliumDRD5IDAHumanPMID:20531939
Cellular ComponentGO:0005886plasma membraneDRD5IDAHumanPMID:10531415
Cellular ComponentGO:0005886plasma membraneDRD5IDAHumanPMID:11500503
Biological ProcessGO:0007191adenylate cyclase-activating dopamine receptor signaling pathwayDRD5IDAHumanPMID:1826762
Biological ProcessGO:0007191adenylate cyclase-activating dopamine receptor signaling pathwayDRD5IDAHumanPMID:18403039
Biological ProcessGO:0007191adenylate cyclase-activating dopamine receptor signaling pathwayDrd5IMPRatRGD:1600979|PMID:15328036
Biological ProcessGO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathwayDRD5IDAHumanPMID:11500503
Biological ProcessGO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathwayDrd5IDAMouseMGI:MGI:3526585|PMID:15598876
Biological ProcessGO:0007189adenylate cyclase-activating G-protein coupled receptor signaling pathwayDrd5IDARatRGD:728422|PMID:1831904
Biological ProcessGO:0008306associative learningDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3688651|PMID:15696326
Biological ProcessGO:0071870cellular response to catecholamine stimulusDRD5IDAHumanPMID:18403039
Biological ProcessGO:0007212dopamine receptor signaling pathwayDrd5IMPRatRGD:1600981|PMID:16855100
Biological ProcessGO:0007212dopamine receptor signaling pathwayDrd5IDARatRGD:728422|PMID:1831904
Biological ProcessGO:0060292long term synaptic depressionDrd5IMPMouseMGI:MGI:3586401|PMID:13679419
Biological ProcessGO:0007617mating behaviorDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3688651|PMID:15696326
Biological ProcessGO:0045776negative regulation of blood pressureDrd5IGIMGI:MGI:109147MouseMGI:MGI:3527993|PMID:12486173
Biological ProcessGO:0045776negative regulation of blood pressureDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3527993|PMID:12486173
Biological ProcessGO:0045776negative regulation of blood pressureDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3526585|PMID:15598876
Biological ProcessGO:0030336negative regulation of cell migrationDrd5IMPRatRGD:1581394|PMID:12688394
Biological ProcessGO:0033861negative regulation of NAD(P)H oxidase activityDRD5IDAHumanPMID:16352863
Biological ProcessGO:0006469negative regulation of protein kinase activityDrd5IMPRatRGD:1581394|PMID:12688394
Biological ProcessGO:0001994norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressureDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3527993|PMID:12486173
Biological ProcessGO:0045762positive regulation of adenylate cyclase activityDRD5IDAHumanPMID:1826762
Biological ProcessGO:0030819positive regulation of cAMP biosynthetic processDrd5IMPRatRGD:1581394|PMID:12688394
Biological ProcessGO:0072593reactive oxygen species metabolic processDRD5IDAHumanPMID:16352863
Biological ProcessGO:0045924regulation of female receptivityDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3688651|PMID:15696326
Biological ProcessGO:0048169regulation of long-term neuronal synaptic plasticityDrd5IMPRatRGD:1600981|PMID:16855100
Biological ProcessGO:0001992regulation of systemic arterial blood pressure by vasopressinDrd5IGIMGI:MGI:1859216|MGI:MGI:1347010MouseMGI:MGI:3527993|PMID:12486173
Biological ProcessGO:0001975response to amphetamineDrd5IGIMGI:MGI:99578MouseMGI:MGI:3610905|PMID:11823893
Biological ProcessGO:0042220response to cocaineDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3610834|PMID:12768268
Biological ProcessGO:0046960sensitizationDrd5IGIMGI:MGI:99578MouseMGI:MGI:3610905|PMID:11823893
Biological ProcessGO:0001963synaptic transmission, dopaminergicDrd5IMPRatRGD:1600981|PMID:16855100
Biological ProcessGO:0019226transmission of nerve impulseDrd5IMPMGI:MGI:2675755MouseMGI:MGI:2667765|PMID:12867509
Biological ProcessGO:0008542visual learningDrd5IMPRatRGD:1600981|PMID:16855100
Biological ProcessGO:0008542visual learningDrd5IMPRatRGD:1600982|PMID:17142305
Biological ProcessGO:0042060wound healingDrd5IMPMGI:MGI:3528074MouseMGI:MGI:3653301|PMID:11595429

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory