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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
20170

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:20170

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:20170
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0031694alpha-2A adrenergic receptor bindingADRA2CIPIUniProtKB:P08913HumanPMID:16605244
Molecular FunctionGO:0004938alpha2-adrenergic receptor activityADRA2CIDAHumanPMID:17215105
Molecular FunctionGO:0004938alpha2-adrenergic receptor activityAdra2cIMPRatRGD:1304256|PMID:12379250
Molecular FunctionGO:0051379epinephrine bindingADRA2CIDAHumanPMID:17215105
Molecular FunctionGO:0004930G-protein coupled receptor activityAdra2cIDAMouseMGI:MGI:3032880|PMID:14712229
Molecular FunctionGO:0005515protein bindingADRA2CIPIUniProtKB:P51693HumanPMID:16531006
Molecular FunctionGO:0046982protein heterodimerization activityADRA2CIPIUniProtKB:P08913HumanPMID:16605244
Molecular FunctionGO:0042803protein homodimerization activityADRA2CIDAHumanPMID:16605244
Cellular ComponentGO:0030424axonAdra2cIDARatRGD:1304339|PMID:15207357
Cellular ComponentGO:0043679axon terminusAdra2cIDARatRGD:1304361|PMID:12591145
Cellular ComponentGO:0005737cytoplasmADRA2CIDAHumanPMID:16605244
Cellular ComponentGO:0005887integral component of plasma membraneADRA2CIDAHumanPMID:16605244
Biological ProcessGO:0071883activation of MAPK activity by adrenergic receptor signaling pathwayADRA2CIDAHumanPMID:17215105
Biological ProcessGO:0032148activation of protein kinase B activityADRA2CIDAHumanPMID:17215105
Biological ProcessGO:0035625epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayADRA2CIDAHumanPMID:17215105
Biological ProcessGO:0007565female pregnancyAdra2cIMPRatRGD:6893569|PMID:19450576
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayAdra2cIDAMouseMGI:MGI:3032880|PMID:14712229
Biological ProcessGO:0070473negative regulation of uterine smooth muscle contractionAdra2cIMPRatRGD:6893570|PMID:17664026
Biological ProcessGO:0045666positive regulation of neuron differentiationADRA2CIDAHumanPMID:17215105
Biological ProcessGO:0045907positive regulation of vasoconstrictionAdra2cIMPRatRGD:6893567|PMID:20862454
Biological ProcessGO:0051930regulation of sensory perception of painAdra2cIMPRatRGD:6893568|PMID:20007733

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory