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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
175

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:175

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:175
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0003682chromatin bindingPdx1IDAMouseMGI:MGI:4366217|PMID:19651901
Molecular FunctionGO:0001046core promoter sequence-specific DNA bindingPdx1IDARatRGD:2311163|PMID:19380737
Molecular FunctionGO:0003677DNA bindingPdx1IDAMouseMGI:MGI:2447494|PMID:12368292
Molecular FunctionGO:0003677DNA bindingPdx1IDAMouseMGI:MGI:3615098|PMID:15486225
Molecular FunctionGO:0003677DNA bindingPdx1IDAMouseMGI:MGI:2676531|PMID:12972592
Molecular FunctionGO:0003677DNA bindingPdx1IDAMouseMGI:MGI:3697248|PMID:17056599
Molecular FunctionGO:0005515protein bindingPdx1IPIUniProtKB:Q6ZWS8MouseMGI:MGI:3041886|PMID:15121856
Molecular FunctionGO:0005515protein bindingPdx1IPIUniProtKB:Q60954-1MouseMGI:MGI:3697248|PMID:17056599
Molecular FunctionGO:0005515protein bindingPdx1IPIUniProtKB:P13405MouseMGI:MGI:4949030|PMID:21399612
Molecular FunctionGO:0005515protein bindingPdx1IPIUniProtKB:Q6ZWS8MouseMGI:MGI:5512841|PMID:17126328
Molecular FunctionGO:0005515protein bindingPdx1IPIRGD:621110RatRGD:2311184|PMID:15885879
Molecular FunctionGO:0005515protein bindingPdx1IPIUniProtKB:Q9WTV5RatRGD:2311184|PMID:15885879
Molecular FunctionGO:0005515protein bindingPdx1IPIRGD:1348463RatRGD:2311191|PMID:15001545
Molecular FunctionGO:0032403protein complex bindingPdx1IPIRGD:3258RatRGD:1598709|PMID:10094480
Molecular FunctionGO:0032403protein complex bindingPdx1IDARatRGD:2311185|PMID:15650027
Molecular FunctionGO:0032403protein complex bindingPdx1IDARatRGD:2311193|PMID:11756538
Molecular FunctionGO:0046982protein heterodimerization activityPdx1IDARatRGD:2311198|PMID:8524276
Molecular FunctionGO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingPdx1IDAMouseMGI:MGI:5572886|PMID:14704343
Molecular FunctionGO:0043565sequence-specific DNA bindingPdx1IDAMouseMGI:MGI:3037232|PMID:14701942
Molecular FunctionGO:0043565sequence-specific DNA bindingPdx1IDARatRGD:1598709|PMID:10094480
Molecular FunctionGO:0003705transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingPdx1IDARatRGD:1598709|PMID:10094480
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingPdx1IDAMouseMGI:MGI:3615098|PMID:15486225
Molecular FunctionGO:0003700transcription factor activity, sequence-specific DNA bindingPdx1IMPRatRGD:1601590|PMID:15151993
Molecular FunctionGO:0008134transcription factor bindingPdx1IPIRGD:1557009RatRGD:2311164|PMID:19264802
Cellular ComponentGO:0005737cytoplasmPdx1IDARatRGD:2311183|PMID:16887799
Cellular ComponentGO:0005737cytoplasmPdx1IDARatRGD:2311186|PMID:15609091
Cellular ComponentGO:0005622intracellularPdx1IDAMouseMGI:MGI:3614320|PMID:15793245
Cellular ComponentGO:0005622intracellularPdx1IDAMouseMGI:MGI:3706893|PMID:10868931
Cellular ComponentGO:0016607nuclear speckPdx1IDAMouseMGI:MGI:3041886|PMID:15121856
Cellular ComponentGO:0005654nucleoplasmPDX1IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:3758555|PMID:11287626
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:3581949|PMID:15888377
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:3771560|PMID:18155690
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:3615098|PMID:15486225
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:3763794|PMID:17928203
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:2447254|PMID:12488434
Cellular ComponentGO:0005634nucleusPdx1IDAMouseMGI:MGI:2686820|PMID:14702043
Cellular ComponentGO:0005634nucleusPdx1IDARatRGD:1598709|PMID:10094480
Biological ProcessGO:0030154cell differentiationPdx1IMPMGI:MGI:2181362MouseMGI:MGI:3612374|PMID:16418487
Biological ProcessGO:0030154cell differentiationPdx1IMPRatRGD:2311194|PMID:11309388
Biological ProcessGO:0051594detection of glucosePdx1IDARatRGD:8553608|PMID:21108535
Biological ProcessGO:0048565digestive tract developmentPdx1IMPMGI:MGI:2388676MouseMGI:MGI:4355651|PMID:19619492
Biological ProcessGO:0031018endocrine pancreas developmentPdx1IMPMGI:MGI:2181360MouseMGI:MGI:3771560|PMID:18155690
Biological ProcessGO:0031017exocrine pancreas developmentPdx1IMPMGI:MGI:2388676MouseMGI:MGI:3610256|PMID:16126192
Biological ProcessGO:0042593glucose homeostasisPdx1IMPMGI:MGI:2181360MouseMGI:MGI:3771560|PMID:18155690
Biological ProcessGO:0042593glucose homeostasisPdx1IGIMGI:MGI:1343085MouseMGI:MGI:4836774|PMID:20811152
Biological ProcessGO:0042593glucose homeostasisPdx1IMPRatRGD:2311197|PMID:11158595
Biological ProcessGO:0006006glucose metabolic processPdx1IDAMouseMGI:MGI:2670470|PMID:12904469
Biological ProcessGO:0030073insulin secretionPDX1IDAHumanPMID:17941991
Biological ProcessGO:0001889liver developmentPdx1IMPMGI:MGI:2388676MouseMGI:MGI:4355651|PMID:19619492
Biological ProcessGO:0016331morphogenesis of embryonic epitheliumPdx1IMPMGI:MGI:2152755MouseMGI:MGI:80614|PMID:8625829
Biological ProcessGO:0008285negative regulation of cell proliferationPdx1IMPMGI:MGI:2181360MouseMGI:MGI:3771560|PMID:18155690
Biological ProcessGO:1902236negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathwayPdx1IMPMGI:MGI:2181360MouseMGI:MGI:4836774|PMID:20811152
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterPdx1IDAMouseMGI:MGI:3697248|PMID:17056599
Biological ProcessGO:0045892negative regulation of transcription, DNA-templatedPdx1IMPRatRGD:2311173|PMID:17641871
Biological ProcessGO:2000675negative regulation of type B pancreatic cell apoptotic processPdx1IMPMGI:MGI:2181360MouseMGI:MGI:4836774|PMID:20811152
Biological ProcessGO:0007263nitric oxide mediated signal transductionPDX1IDAHumanPMID:17941991
Biological ProcessGO:0031016pancreas developmentPdx1IMPMGI:MGI:2181362MouseMGI:MGI:3612374|PMID:16418487
Biological ProcessGO:0031016pancreas developmentPdx1IMPMGI:MGI:2152755MouseMGI:MGI:80614|PMID:8625829
Biological ProcessGO:0010942positive regulation of cell deathPdx1IMPRatRGD:2311201|PMID:10580420
Biological ProcessGO:0008284positive regulation of cell proliferationPdx1IMPMGI:MGI:2181360MouseMGI:MGI:3771560|PMID:18155690
Biological ProcessGO:0008284positive regulation of cell proliferationPdx1IMPRatRGD:2311197|PMID:11158595
Biological ProcessGO:0043388positive regulation of DNA bindingPdx1IMPRatRGD:2311195|PMID:11181516
Biological ProcessGO:0032024positive regulation of insulin secretionPdx1IMPRatRGD:2306975|PMID:18439098
Biological ProcessGO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulusPdx1IMPMouseMGI:MGI:5311513|PMID:22253604
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPdx1IDAMouseMGI:MGI:3037232|PMID:14701942
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPdx1IDAMouseMGI:MGI:3615098|PMID:15486225
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPdx1IDAMouseMGI:MGI:5574299|PMID:19799567
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPdx1IDARatRGD:1598709|PMID:10094480
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterPdx1IMPRatRGD:8553608|PMID:21108535
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPdx1IDAMouseMGI:MGI:2447494|PMID:12368292
Biological ProcessGO:0045893positive regulation of transcription, DNA-templatedPdx1IMPRatRGD:2311168|PMID:18253862
Biological ProcessGO:0042127regulation of cell proliferationPdx1IDAMouseMGI:MGI:2447254|PMID:12488434
Biological ProcessGO:0010468regulation of gene expressionPdx1IMPRatRGD:10047145|PMID:10802714
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterPdx1IMPMouseMGI:MGI:2676531|PMID:12972592
Biological ProcessGO:0006357regulation of transcription from RNA polymerase II promoterPdx1IDAMouseMGI:MGI:3037232|PMID:14701942
Biological ProcessGO:0009749response to glucosePdx1IMPRatRGD:2311189|PMID:15148392
Biological ProcessGO:0007224smoothened signaling pathwayPdx1IMPRatRGD:2311195|PMID:11181516
Biological ProcessGO:0048863stem cell differentiationPdx1IMPRatRGD:2311168|PMID:18253862
Biological ProcessGO:0006366transcription from RNA polymerase II promoterPdx1IMPRatRGD:1601590|PMID:15151993
Biological ProcessGO:0006351transcription, DNA-templatedPdx1IMPRatRGD:1601590|PMID:15151993
Biological ProcessGO:0003309type B pancreatic cell differentiationPDX1IDAHumanPMID:12124776
Biological ProcessGO:0003309type B pancreatic cell differentiationPDX1IDAHumanPMID:24567802
Biological ProcessGO:0003309type B pancreatic cell differentiationPdx1IMPRatRGD:8553608|PMID:21108535

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/18/2018
MGI 6.12
The Jackson Laboratory