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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1387

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:1387

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:1387
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0016493C-C chemokine receptor activityCcr7IMPMGI:MGI:2180679MouseMGI:MGI:1346262|PMID:10520991
Molecular FunctionGO:0038117C-C motif chemokine 19 receptor activityCCR7IDAHumanPMID:9507024
Molecular FunctionGO:0038121C-C motif chemokine 21 receptor activityCCR7IDAHumanPMID:9507024
Molecular FunctionGO:0035757chemokine (C-C motif) ligand 19 bindingCCR7IPIUniProtKB:O70460HumanPMID:9507024
Molecular FunctionGO:0035758chemokine (C-C motif) ligand 21 bindingCCR7IPIUniProtKB:P84444HumanPMID:9507024
Molecular FunctionGO:0005515protein bindingCcr7IPIUniProtKB:P20963MouseMGI:MGI:5447878|PMID:22922463
Cellular ComponentGO:0005623cellCcr7IMPMouseMGI:MGI:4441559|PMID:20176793
Cellular ComponentGO:0009897external side of plasma membraneCcr7IDAMouseMGI:MGI:3818206|PMID:19008373
Cellular ComponentGO:0005622intracellularCCR7IDAHumanPMID:21051556
Cellular ComponentGO:0005622intracellularCcr7IDAMouseMGI:MGI:4888468|PMID:21051556
Cellular ComponentGO:0005886plasma membraneCCR7IDAHumanPMID:21051556
Cellular ComponentGO:0005886plasma membraneCcr7IDAMouseMGI:MGI:4888468|PMID:21051556
Biological ProcessGO:0038115chemokine (C-C motif) ligand 19 signaling pathwayCCR7IDAHumanPMID:9507024
Biological ProcessGO:0038116chemokine (C-C motif) ligand 21 signaling pathwayCCR7IDAHumanPMID:9507024
Biological ProcessGO:0070098chemokine-mediated signaling pathwayCCR7IDAHumanPMID:9507024
Biological ProcessGO:0070098chemokine-mediated signaling pathwayCcr7IMPMGI:MGI:2180679MouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:0006935chemotaxisCcr7IMPMGI:MGI:2180679MouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:0019221cytokine-mediated signaling pathwayCCR7IDAHumanPMID:9507024
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayCcr7IMPMGI:MGI:2180679MouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:0006955immune responseCcr7IMPMGI:MGI:2180679MouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:0072610interleukin-12 secretionCcr7IMPMouseMGI:MGI:4441559|PMID:20176793
Biological ProcessGO:0097029mature dendritic cell differentiationCcr7IMPMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:0045060negative thymic T cell selectionCcr7IMPMouseMGI:MGI:3847607|PMID:17785582
Biological ProcessGO:0002606positive regulation of dendritic cell antigen processing and presentationCcr7IDAMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:2000510positive regulation of dendritic cell chemotaxisCcr7IMPMouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:2000526positive regulation of glycoprotein biosynthetic process involved in immunological synapse formationCcr7IMPMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:0002922positive regulation of humoral immune responseCcr7IMPMouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:0002885positive regulation of hypersensitivityCcr7IMPMouseMGI:MGI:1346262|PMID:10520991
Biological ProcessGO:2000522positive regulation of immunological synapse formationCcr7IMPMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:0032735positive regulation of interleukin-12 productionCcr7IMPMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:0090023positive regulation of neutrophil chemotaxisCCR7IDAHumanPMID:21051556
Biological ProcessGO:0090023positive regulation of neutrophil chemotaxisCcr7IMPMouseMGI:MGI:4888468|PMID:21051556
Biological ProcessGO:2000525positive regulation of T cell costimulationCcr7IMPMouseMGI:MGI:3576832|PMID:15845453
Biological ProcessGO:0050862positive regulation of T cell receptor signaling pathwayCcr7IMPMouseMGI:MGI:3847607|PMID:17785582
Biological ProcessGO:0032649regulation of interferon-gamma productionCcr7IMPMouseMGI:MGI:4441559|PMID:20176793
Biological ProcessGO:0050706regulation of interleukin-1 beta secretionCcr7IMPMouseMGI:MGI:4441559|PMID:20176793
Biological ProcessGO:0032496response to lipopolysaccharideCcr7IDAMouseMGI:MGI:5285155|PMID:20638137

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory