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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
128661

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:128661

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Apr 25 11:11:33 2017.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:128661
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:004702015-hydroxyprostaglandin-D dehydrogenase (NADP+) activityAKR1C3IDAHumanPMID:22170488
Molecular FunctionGO:004700617-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAkr1c18IDAMouseMGI:MGI:3526508|PMID:15471942
Molecular FunctionGO:004700617-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAkr1c18IMPMGI:MGI:3527218MouseMGI:MGI:3526508|PMID:15471942
Molecular FunctionGO:004700617-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAkr1c3IDARatRGD:10053609|PMID:8977402
Molecular FunctionGO:004700617-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAkr1c3IDARatRGD:1299435|PMID:8172618
Molecular FunctionGO:004700617-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activityAkr1c3IDARatRGD:2303525|PMID:4392955
Molecular FunctionGO:0004032alditol:NADP+ 1-oxidoreductase activityAKR1C3IDAHumanPMID:21232532
Molecular FunctionGO:0004032alditol:NADP+ 1-oxidoreductase activityAkr1c3IDARatRGD:10053609|PMID:8977402
Molecular FunctionGO:0004033aldo-keto reductase (NADP) activityAkr1c3IDARatRGD:10053609|PMID:8977402
Molecular FunctionGO:0047023androsterone dehydrogenase activityAKR1C3IDAHumanPMID:16983398
Molecular FunctionGO:0047787delta4-3-oxosteroid 5beta-reductase activityAKR1C3IDAHumanPMID:16983398
Molecular FunctionGO:0035410dihydrotestosterone 17-beta-dehydrogenase activityAKR1C3IDAHumanPMID:16983398
Molecular FunctionGO:0045550geranylgeranyl reductase activityAKR1C3IDAHumanPMID:21187079
Molecular FunctionGO:0045703ketoreductase activityAKR1C3IDAHumanPMID:19487289
Molecular FunctionGO:0047086ketosteroid monooxygenase activityAKR1C3IDAHumanPMID:21232532
Molecular FunctionGO:0016655oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorAKR1C3IDAHumanPMID:19442656
Molecular FunctionGO:0016655oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorAKR1C3IDAHumanPMID:20837989
Molecular FunctionGO:0018636phenanthrene 9,10-monooxygenase activityAKR1C3IDAHumanPMID:21851338
Molecular FunctionGO:0001758retinal dehydrogenase activityAKR1C3IDAHumanPMID:21851338
Molecular FunctionGO:0004745retinol dehydrogenase activityAKR1C3IDAHumanPMID:21851338
Cellular ComponentGO:0005737cytoplasmAKR1C3IDAHumanPMID:18574251
Cellular ComponentGO:0005737cytoplasmAKR1C3IDAHumanPMID:19336506
Cellular ComponentGO:0005737cytoplasmAKR1C3IDAHumanPMID:19942269
Cellular ComponentGO:0005737cytoplasmAKR1C3IDAHumanPMID:22170488
Cellular ComponentGO:0005737cytoplasmAkr1c3IDARatRGD:8554615|PMID:18574251
Cellular ComponentGO:0005829cytosolAkr1c3IDARatRGD:1299434|PMID:8194472
Cellular ComponentGO:0070062extracellular exosomeAKR1C3IDAHumanPMID:23376485
Cellular ComponentGO:0070062extracellular exosomeAKR1C3IDAHumanPMID:23533145
Cellular ComponentGO:0005622intracellularAKR1C3IDAHumanGO_REF:0000054
Cellular ComponentGO:0005634nucleusAKR1C3IDAHumanPMID:18574251
Cellular ComponentGO:0005634nucleusAkr1c3IDARatRGD:8554615|PMID:18574251
Biological ProcessGO:0071276cellular response to cadmium ionAKR1C3IDAHumanPMID:21787718
Biological ProcessGO:0071277cellular response to calcium ionAKR1C3IDAHumanPMID:22170488
Biological ProcessGO:0071384cellular response to corticosteroid stimulusAKR1C3IDAHumanPMID:19336506
Biological ProcessGO:0071395cellular response to jasmonic acid stimulusAKR1C3IDAHumanPMID:19487289
Biological ProcessGO:0071799cellular response to prostaglandin D stimulusAKR1C3IDAHumanPMID:18508192
Biological ProcessGO:0071379cellular response to prostaglandin stimulusAKR1C3IDAHumanPMID:22170488
Biological ProcessGO:0034614cellular response to reactive oxygen speciesAKR1C3IDAHumanPMID:21787718
Biological ProcessGO:0071560cellular response to transforming growth factor beta stimulusAkr1c3IMPRatRGD:10053613|PMID:2401226
Biological ProcessGO:0044597daunorubicin metabolic processAKR1C3IMPHumanPMID:20837989
Biological ProcessGO:0044598doxorubicin metabolic processAKR1C3IMPHumanPMID:20837989
Biological ProcessGO:0016488farnesol catabolic processAKR1C3IDAHumanPMID:21187079
Biological ProcessGO:0007186G-protein coupled receptor signaling pathwayAKR1C3IDAHumanPMID:18508192
Biological ProcessGO:1900053negative regulation of retinoic acid biosynthetic processAKR1C3IDAHumanPMID:21851338
Biological ProcessGO:0055114oxidation-reduction processAKR1C3IDAHumanPMID:16983398
Biological ProcessGO:0055114oxidation-reduction processAKR1C3IDAHumanPMID:19442656
Biological ProcessGO:0055114oxidation-reduction processAKR1C3IDAHumanPMID:21232532
Biological ProcessGO:0007567parturitionAkr1c18IMPMGI:MGI:3527218MouseMGI:MGI:3526508|PMID:15471942
Biological ProcessGO:0010942positive regulation of cell deathAKR1C3IDAHumanPMID:21787718
Biological ProcessGO:0008284positive regulation of cell proliferationAKR1C3IDAHumanPMID:18508192
Biological ProcessGO:0008284positive regulation of cell proliferationAKR1C3IDAHumanPMID:20036328
Biological ProcessGO:0008284positive regulation of cell proliferationAKR1C3IMPHumanPMID:21851338
Biological ProcessGO:2000353positive regulation of endothelial cell apoptotic processAKR1C3IDAHumanPMID:19442656
Biological ProcessGO:0051897positive regulation of protein kinase B signalingAKR1C3IDAHumanPMID:18508192
Biological ProcessGO:2000379positive regulation of reactive oxygen species metabolic processAKR1C3IDAHumanPMID:19442656
Biological ProcessGO:0006709progesterone catabolic processAkr1c18IDAMouseMGI:MGI:3526508|PMID:15471942
Biological ProcessGO:0006709progesterone catabolic processAkr1c18IMPMGI:MGI:3527218MouseMGI:MGI:3526508|PMID:15471942
Biological ProcessGO:0042448progesterone metabolic processAKR1C3IDAHumanPMID:21232532
Biological ProcessGO:0042448progesterone metabolic processAkr1c3IDARatRGD:1299435|PMID:8172618
Biological ProcessGO:0042448progesterone metabolic processAkr1c3IDARatRGD:2303525|PMID:4392955
Biological ProcessGO:0000060protein import into nucleus, translocationAKR1C3IDAHumanPMID:21787718
Biological ProcessGO:0048385regulation of retinoic acid receptor signaling pathwayAKR1C3IDAHumanPMID:21851338
Biological ProcessGO:0050810regulation of steroid biosynthetic processAkr1c3IDARatRGD:2303525|PMID:4392955
Biological ProcessGO:2000224regulation of testosterone biosynthetic processAKR1C3IMPHumanPMID:19336506
Biological ProcessGO:0042574retinal metabolic processAKR1C3IDAHumanPMID:21851338
Biological ProcessGO:0061370testosterone biosynthetic processAKR1C3IMPHumanPMID:16983398

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/09/2019
MGI 6.13
The Jackson Laboratory