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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
12832

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:12832

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:12832
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0045519interleukin-23 receptor bindingIL23AIDAHumanPMID:11114383
Molecular FunctionGO:0045519interleukin-23 receptor bindingIl23aIPIUniProtKB:Q60837MouseMGI:MGI:1927676|PMID:11114383
Molecular FunctionGO:0005515protein bindingIl23aIPIUniProtKB:P29460|UniProtKB:P43432MouseMGI:MGI:1927676|PMID:11114383
Cellular ComponentGO:0005615extracellular spaceIl23aIDAMouseMGI:MGI:4881588|PMID:21148126
Cellular ComponentGO:0070743interleukin-23 complexIL23AIDAHumanPMID:11114383
Biological ProcessGO:0050829defense response to Gram-negative bacteriumIL23AIDAHumanPMID:15114670
Biological ProcessGO:0050829defense response to Gram-negative bacteriumIL23AIDAHumanPMID:20027291
Biological ProcessGO:0032693negative regulation of interleukin-10 productionIL23AIMPHumanPMID:16751425
Biological ProcessGO:0042104positive regulation of activated T cell proliferationIL23AIDAHumanPMID:11114383
Biological ProcessGO:0010535positive regulation of activation of JAK2 kinase activityIL23AIDAHumanPMID:12023369
Biological ProcessGO:0002230positive regulation of defense response to virus by hostIL23AIDAHumanPMID:12421946
Biological ProcessGO:0002230positive regulation of defense response to virus by hostIl23aIDAMouseMGI:MGI:3027369|PMID:14688363
Biological ProcessGO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionIL23AIDAHumanPMID:20027291
Biological ProcessGO:0032729positive regulation of interferon-gamma productionIL23AIDAHumanPMID:11114383
Biological ProcessGO:0032729positive regulation of interferon-gamma productionIL23AIDAHumanPMID:17888176
Biological ProcessGO:0032729positive regulation of interferon-gamma productionIL23AIDAHumanPMID:20027291
Biological ProcessGO:0032733positive regulation of interleukin-10 productionIL23AIDAHumanPMID:15265908
Biological ProcessGO:0032735positive regulation of interleukin-12 productionIL23AIDAHumanPMID:20027291
Biological ProcessGO:0032740positive regulation of interleukin-17 productionIL23AIDAHumanPMID:16482511
Biological ProcessGO:0032740positive regulation of interleukin-17 productionIL23AIDAHumanPMID:16751425
Biological ProcessGO:0032740positive regulation of interleukin-17 productionIL23AIDAHumanPMID:17888176
Biological ProcessGO:0043382positive regulation of memory T cell differentiationIl23aIDAMouseMGI:MGI:3027369|PMID:14688363
Biological ProcessGO:0032819positive regulation of natural killer cell proliferationIL23AIDAHumanPMID:19088061
Biological ProcessGO:0090023positive regulation of neutrophil chemotaxisIl23aIDAMouseMGI:MGI:3841502|PMID:19289819
Biological ProcessGO:0051135positive regulation of NK T cell activationIL23AIDAHumanPMID:19088061
Biological ProcessGO:0051142positive regulation of NK T cell proliferationIL23AIDAHumanPMID:19088061
Biological ProcessGO:0045672positive regulation of osteoclast differentiationIL23AIDAHumanPMID:17888176
Biological ProcessGO:0001916positive regulation of T cell mediated cytotoxicityIl23aIDAMouseMGI:MGI:3027369|PMID:14688363
Biological ProcessGO:0042102positive regulation of T cell proliferationIL23AIDAHumanPMID:12023369
Biological ProcessGO:0002827positive regulation of T-helper 1 type immune responseIL23AIDAHumanPMID:15114670
Biological ProcessGO:0002827positive regulation of T-helper 1 type immune responseIl23aIDAMouseMGI:MGI:3027369|PMID:14688363
Biological ProcessGO:2000330positive regulation of T-helper 17 cell lineage commitmentIl23aIDAMouseMGI:MGI:3851279|PMID:19501566
Biological ProcessGO:2000318positive regulation of T-helper 17 type immune responseIl23aIDAMouseMGI:MGI:3851279|PMID:19501566
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIl23aIGIMGI:MGI:96543|MGI:MGI:96542MouseMGI:MGI:4355633|PMID:19666510
Biological ProcessGO:0032760positive regulation of tumor necrosis factor productionIL23AIMPHumanPMID:16751425
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinIL23AIDAHumanPMID:12023369
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinIL23AIDAHumanPMID:19088061
Biological ProcessGO:0042520positive regulation of tyrosine phosphorylation of Stat4 proteinIL23AIDAHumanPMID:11114383
Biological ProcessGO:0042520positive regulation of tyrosine phosphorylation of Stat4 proteinIL23AIDAHumanPMID:12023369
Biological ProcessGO:0042520positive regulation of tyrosine phosphorylation of Stat4 proteinIL23AIDAHumanPMID:19088061
Biological ProcessGO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinIL23AIDAHumanPMID:12023369
Biological ProcessGO:0042510regulation of tyrosine phosphorylation of Stat1 proteinIL23AIDAHumanPMID:12023369
Biological ProcessGO:0042098T cell proliferationIl23aIDAMouseMGI:MGI:3722056|PMID:16982811

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory