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Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
124414

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:124414

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Jan 27 18:25:03 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:124414
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0030898actin-dependent ATPase activityMYH6IMPHumanPMID:16088376
Molecular FunctionGO:0005524ATP bindingMyh6IDARatRGD:1581167|PMID:10651160
Molecular FunctionGO:0005524ATP bindingMyh6IMPRatRGD:1581170|PMID:15471982
Molecular FunctionGO:0016887ATPase activityMYH6IDAHumanPMID:15621050
Molecular FunctionGO:0030899calcium-dependent ATPase activityMyh6IMPRatRGD:1581167|PMID:10651160
Molecular FunctionGO:0042802identical protein bindingMyh6IPIUniProtKB:P02563RatPMID:22728135
Molecular FunctionGO:0042802identical protein bindingMyh6IPIUniProtKB:P02563RatPMID:22728135
Molecular FunctionGO:0000146microfilament motor activityMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Molecular FunctionGO:0000146microfilament motor activityMyh6IMPMGI:MGI:3690299MouseMGI:MGI:3689292|PMID:16983074
Molecular FunctionGO:0000146microfilament motor activityMyh6IMPRatRGD:1581168|PMID:15020307
Molecular FunctionGO:0005515protein bindingMyh6IPIUniProtKB:O70468MouseMGI:MGI:3695637|PMID:17075052
Molecular FunctionGO:0046982protein heterodimerization activityMyh6IDARatRGD:1581165|PMID:3693405
Molecular FunctionGO:0042803protein homodimerization activityMyh6IDARatRGD:1581165|PMID:3693405
Molecular FunctionGO:0019901protein kinase bindingMYH6IPIUniProtKB:Q8IWU2HumanPMID:18029400
Molecular FunctionGO:0019901protein kinase bindingMYH6IPIUniProtKB:Q8IWU2HumanPMID:18429820
Molecular FunctionGO:0008307structural constituent of muscleMYH6IDAHumanPMID:15621050
Molecular FunctionGO:0008307structural constituent of muscleMYH6IDAHumanPMID:16088376
Cellular ComponentGO:0005737cytoplasmMYH6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005737cytoplasmMyh6IDARatRGD:1581166|PMID:9359883
Cellular ComponentGO:0005925focal adhesionMYH6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005739mitochondrionMyh6IDARatRGD:7327223|PMID:20533907
Cellular ComponentGO:0005859muscle myosin complexMyh6IDARatRGD:1581165|PMID:3693405
Cellular ComponentGO:0030016myofibrilMyh6IDAMouseMGI:MGI:83539|PMID:8878443
Cellular ComponentGO:0030016myofibrilMyh6IDAMouseMGI:MGI:1327483|PMID:9884344
Cellular ComponentGO:0030016myofibrilMyh6IDARatRGD:1581167|PMID:10651160
Cellular ComponentGO:0016459myosin complexMyh6IDAMouseMGI:MGI:1195842|PMID:8482409
Cellular ComponentGO:0016459myosin complexMyh6IDAMouseMGI:MGI:1327483|PMID:9884344
Cellular ComponentGO:0016459myosin complexMyh6IDAMouseMGI:MGI:3526615|PMID:15001446
Cellular ComponentGO:0005730nucleolusMYH6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005634nucleusMYH6IDAHumanGO_REF:0000052
Cellular ComponentGO:0001725stress fiberMyh6IDAMouseMGI:MGI:4936789|PMID:21126233
Cellular ComponentGO:0030018Z discMyh6IDAMouseMGI:MGI:4936789|PMID:21126233
Biological ProcessGO:0030048actin filament-based movementMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Biological ProcessGO:0007512adult heart developmentMYH6IMPHumanPMID:15735645
Biological ProcessGO:0007512adult heart developmentMYH6IMPHumanPMID:15998695
Biological ProcessGO:0007512adult heart developmentMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0007512adult heart developmentMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1327483|PMID:9884344
Biological ProcessGO:0007512adult heart developmentMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1333559|PMID:10066683
Biological ProcessGO:0007512adult heart developmentMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Biological ProcessGO:0007512adult heart developmentMyh6IMPMGI:MGI:3690299|MGI:MGI:3690300MouseMGI:MGI:3689292|PMID:16983074
Biological ProcessGO:0006200ATP catabolic processMYH6IDAHumanPMID:15621050
Biological ProcessGO:0006200ATP catabolic processMYH6IMPHumanPMID:16088376
Biological ProcessGO:0006200ATP catabolic processMyh6IMPRatRGD:1581170|PMID:15471982
Biological ProcessGO:0055009atrial cardiac muscle tissue morphogenesisMYH6IMPHumanPMID:15735645
Biological ProcessGO:0030509BMP signaling pathwayMyh6IDAMouseMGI:MGI:3703823|PMID:17360443
Biological ProcessGO:0060070canonical Wnt signaling pathwayMyh6IDAMouseMGI:MGI:3703823|PMID:17360443
Biological ProcessGO:0048739cardiac muscle fiber developmentMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0048739cardiac muscle fiber developmentMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1327483|PMID:9884344
Biological ProcessGO:0048739cardiac muscle fiber developmentMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1333559|PMID:10066683
Biological ProcessGO:0048739cardiac muscle fiber developmentMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Biological ProcessGO:0001701in utero embryonic developmentMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0008152metabolic processMYH6IDAHumanPMID:15621050
Biological ProcessGO:0008152metabolic processMYH6IMPHumanPMID:16088376
Biological ProcessGO:0006936muscle contractionMYH6IDAHumanPMID:15621050
Biological ProcessGO:0006936muscle contractionMyh6IMPRatRGD:1581168|PMID:15020307
Biological ProcessGO:0006936muscle contractionMyh6IMPRatRGD:1581170|PMID:15471982
Biological ProcessGO:0030049muscle filament slidingMYH6IMPHumanPMID:16088376
Biological ProcessGO:0030239myofibril assemblyMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0030239myofibril assemblyMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1327483|PMID:9884344
Biological ProcessGO:0030239myofibril assemblyMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1333559|PMID:10066683
Biological ProcessGO:0043462regulation of ATPase activityMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Biological ProcessGO:0008217regulation of blood pressureMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:80448|PMID:8614836
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1327483|PMID:9884344
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1332374|PMID:10074482
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1333559|PMID:10066683
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1344104|PMID:10231857
Biological ProcessGO:0008016regulation of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:3664144|PMID:9045856
Biological ProcessGO:0060420regulation of heart growthMyh6IDAMouseMGI:MGI:3708230|PMID:17379774
Biological ProcessGO:0002027regulation of heart rateMYH6IDAHumanPMID:15621050
Biological ProcessGO:0002027regulation of heart rateMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1202509|PMID:9541509
Biological ProcessGO:0002026regulation of the force of heart contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1202509|PMID:9541509
Biological ProcessGO:0045214sarcomere organizationMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:80448|PMID:8614836
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:3652543MouseMGI:MGI:83539|PMID:8878443
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1202509|PMID:9541509
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1327483|PMID:9884344
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1332374|PMID:10074482
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:1333559|PMID:10066683
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704|MGI:MGI:3664197MouseMGI:MGI:3526615|PMID:15001446
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:2182704MouseMGI:MGI:3664144|PMID:9045856
Biological ProcessGO:0006941striated muscle contractionMyh6IMPMGI:MGI:3690299|MGI:MGI:3690300MouseMGI:MGI:3689292|PMID:16983074
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisMYH6IMPHumanPMID:11815426
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisMYH6IMPHumanPMID:15998695
Biological ProcessGO:0007522visceral muscle developmentMyh6IMPMGI:MGI:2182704MouseMGI:MGI:3039200|PMID:11708849

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory