About   Help   FAQ
Comparative GO Graph (mouse, human, rat)
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
1242

Compare experimental GO annotations for Human-Mouse-Rat HomoloGene:1242

Graphs for Molecular Function, Cellular Component, Biological Process generated Tue Aug 5 20:57:06 2014.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human and rat homologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Mouse-Rat genes in HomoloGene:1242
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0034190apolipoprotein receptor bindingAPOA2IPIUniProtKB:O95477HumanPMID:11162594
Molecular FunctionGO:0015485cholesterol bindingAPOA2IDAHumanPMID:218942
Molecular FunctionGO:0017127cholesterol transporter activityAPOA2IDAHumanPMID:9651324
Molecular FunctionGO:0017127cholesterol transporter activityApoa2IDARatRGD:1626399|PMID:1537840
Molecular FunctionGO:0008035high-density lipoprotein particle bindingApoa2IMPMGI:MGI:2157148MouseMGI:MGI:3037533|PMID:14729860
Molecular FunctionGO:0070653high-density lipoprotein particle receptor bindingAPOA2IPIUniProtKB:Q8WTV0HumanPMID:10764676
Molecular FunctionGO:0055102lipase inhibitor activityAPOA2IDAHumanPMID:14967812
Molecular FunctionGO:0008289lipid bindingAPOA2IDAHumanPMID:14967812
Molecular FunctionGO:0005319lipid transporter activityAPOA2IDAHumanPMID:1606170
Molecular FunctionGO:0031210phosphatidylcholine bindingAPOA2IDAHumanPMID:17264082
Molecular FunctionGO:0060228phosphatidylcholine-sterol O-acyltransferase activator activityAPOA2IDAHumanPMID:14967812
Molecular FunctionGO:0005543phospholipid bindingAPOA2IDAHumanPMID:218942
Molecular FunctionGO:0005515protein bindingAPOA2IPIUniProtKB:Q8NCW5HumanPMID:11991719
Molecular FunctionGO:0005515protein bindingAPOA2IPIUniProtKB:Q92597HumanPMID:17786215
Molecular FunctionGO:0046982protein heterodimerization activityAPOA2IPIUniProtKB:P05090HumanPMID:7918467
Molecular FunctionGO:0046982protein heterodimerization activityAPOA2IPIUniProtKB:P02649HumanPMID:8245722
Molecular FunctionGO:0046982protein heterodimerization activityAPOA2IPIUniProtKB:P04114HumanPMID:8245722
Molecular FunctionGO:0042803protein homodimerization activityAPOA2IDAHumanPMID:17264082
Cellular ComponentGO:0072562blood microparticleAPOA2IDAHumanPMID:22516433
Cellular ComponentGO:0042627chylomicronAPOA2IDAHumanPMID:8245722
Cellular ComponentGO:0005615extracellular spaceApoa2IDAMouseMGI:MGI:49599|PMID:1596514
Cellular ComponentGO:0005615extracellular spaceApoa2IDAMouseMGI:MGI:55488|PMID:6403543
Cellular ComponentGO:0005615extracellular spaceApoa2IDAMouseMGI:MGI:892202|PMID:9186920
Cellular ComponentGO:0070062extracellular vesicular exosomeAPOA2IDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular vesicular exosomeAPOA2IDAHumanPMID:19199708
Cellular ComponentGO:0070062extracellular vesicular exosomeAPOA2IDAHumanPMID:23376485
Cellular ComponentGO:0034364high-density lipoprotein particleAPOA2IDAHumanPMID:17264082
Cellular ComponentGO:0034364high-density lipoprotein particleAPOA2IDAHumanPMID:210174
Cellular ComponentGO:0034364high-density lipoprotein particleAPOA2IDAHumanPMID:3104518
Cellular ComponentGO:0034366spherical high-density lipoprotein particleAPOA2IDAHumanPMID:16682745
Cellular ComponentGO:0034361very-low-density lipoprotein particleAPOA2IDAHumanPMID:8245722
Biological ProcessGO:0033344cholesterol effluxAPOA2IDAHumanPMID:11162594
Biological ProcessGO:0042632cholesterol homeostasisAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0042632cholesterol homeostasisApoa2IDAMouseMGI:MGI:53216|PMID:8422330
Biological ProcessGO:0042632cholesterol homeostasisApoa2IMPMGI:MGI:2157148MouseMGI:MGI:1339279|PMID:10357838
Biological ProcessGO:0042632cholesterol homeostasisApoa2IGIMGI:MGI:96216MouseMGI:MGI:1339279|PMID:10357838
Biological ProcessGO:0008203cholesterol metabolic processApoa2IMPMGI:MGI:2157148MouseMGI:MGI:1339279|PMID:10357838
Biological ProcessGO:0008203cholesterol metabolic processApoa2IGIMGI:MGI:96216MouseMGI:MGI:1339279|PMID:10357838
Biological ProcessGO:0008203cholesterol metabolic processApoa2IMPMGI:MGI:2157148MouseMGI:MGI:2180727|PMID:8647961
Biological ProcessGO:0030301cholesterol transportApoa2IDARatRGD:1626399|PMID:1537840
Biological ProcessGO:0046340diacylglycerol catabolic processAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0034380high-density lipoprotein particle assemblyAPOA2IDAHumanPMID:218942
Biological ProcessGO:0034384high-density lipoprotein particle clearanceAPOA2IDAHumanPMID:10764676
Biological ProcessGO:0034375high-density lipoprotein particle remodelingAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0034375high-density lipoprotein particle remodelingAPOA2IDAHumanPMID:8106353
Biological ProcessGO:0006869lipid transportApoa2IMPMGI:MGI:2157148MouseMGI:MGI:3037533|PMID:14729860
Biological ProcessGO:0042157lipoprotein metabolic processApoa2IDAMouseMGI:MGI:70383|PMID:7837794
Biological ProcessGO:0042157lipoprotein metabolic processApoa2IDAMouseMGI:MGI:87210|PMID:9150245
Biological ProcessGO:0034374low-density lipoprotein particle remodelingAPOA2IDAHumanPMID:8106353
Biological ProcessGO:0060621negative regulation of cholesterol importAPOA2IDAHumanPMID:10764676
Biological ProcessGO:0032375negative regulation of cholesterol transportAPOA2IMPHumanPMID:8636092
Biological ProcessGO:0060695negative regulation of cholesterol transporter activityAPOA2IDAHumanPMID:8106353
Biological ProcessGO:0002740negative regulation of cytokine secretion involved in immune responseAPOA2IDAHumanPMID:12458630
Biological ProcessGO:0060192negative regulation of lipase activityAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0060192negative regulation of lipase activityApoa2IMPMGI:MGI:2157148MouseMGI:MGI:1339279|PMID:10357838
Biological ProcessGO:0050995negative regulation of lipid catabolic processAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0010903negative regulation of very-low-density lipoprotein particle remodelingAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0031100organ regenerationApoa2IDARatRGD:1599161|PMID:2123716
Biological ProcessGO:0018206peptidyl-methionine modificationAPOA2IDAHumanPMID:12576517
Biological ProcessGO:0006656phosphatidylcholine biosynthetic processAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0009395phospholipid catabolic processAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0033700phospholipid effluxAPOA2IDAHumanPMID:11162594
Biological ProcessGO:0043085positive regulation of catalytic activityAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0010873positive regulation of cholesterol esterificationAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0045416positive regulation of interleukin-8 biosynthetic processAPOA2IDAHumanPMID:11591715
Biological ProcessGO:0050996positive regulation of lipid catabolic processAPOA2IDAHumanPMID:8640403
Biological ProcessGO:0006457protein foldingAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0018158protein oxidationAPOA2IDAHumanPMID:12576517
Biological ProcessGO:0030300regulation of intestinal cholesterol absorptionApoa2IMPMGI:MGI:2157148MouseMGI:MGI:84652|PMID:8962133
Biological ProcessGO:0031647regulation of protein stabilityAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0009749response to glucoseAPOA2IDAHumanPMID:14988251
Biological ProcessGO:0043691reverse cholesterol transportAPOA2IDAHumanPMID:14967812
Biological ProcessGO:0034370triglyceride-rich lipoprotein particle remodelingAPOA2IDAHumanPMID:14967812

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory