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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TOP2A HGNC:11989 (HGNC)
7153 (Entrez Gene)
126430 (OMIM)
TOP2A (MyGene.info)
HGNC homology
Chr17 q21.2 Chr17:40388521-40417950 (-)
P11388 (UniProt | EBI)
NM_001067 (RefSeq)
mouse Top2a MGI:98790 (MGI)
21973 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 62.91 cM Chr11:98992943-99024189 (-)
ENSMUSG00000020914 (Ensembl Gene Model)
ENSMUSP00000068896 (Ensembl)
ENSMUST00000068031 (Ensembl)
rat Top2a 360243 (Entrez Gene)
Chr10 q31 P41516 (UniProt | EBI)
NM_022183 (RefSeq)
chimpanzee TOP2A 454651 (Entrez Gene)
Chr17 XP_016787335 (RefSeq)
cattle TOP2A 787696 (Entrez Gene)
Chr19 XP_005220838 (RefSeq)
dog TOP2A 480525 (Entrez Gene)
Chr9 XP_537646 (RefSeq)
chicken TOP2A 395570 (Entrez Gene)
Chr27 O42130 (UniProt | EBI)
NM_204791 (RefSeq)
zebrafish top2a 323733 (Entrez Gene)
Chr12 NP_001296944 (RefSeq)
NM_001003834 (RefSeq)
frog, western clawed top2a 100038293 (Entrez Gene)
Chr10 XP_002942632 (RefSeq)
macaque, rhesus TOP2A 700707 (Entrez Gene)
Chr16 XP_014975075 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory