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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
7810

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LARGE HGNC:6511 (HGNC)
9215 (Entrez Gene)
603590 (OMIM)
Chr22 q12.3 Chr22:33272523-33920476 (-)
GRCh38
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 1; MDDGA1
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 6; MDDGA6
Muscular Dystrophy-Dystroglycanopathy (congenital with Mental Retardation), Type B, 6; MDDGB6
O95461 (UniProt | EBI)
NM_004737 (RefSeq)
mouse Large MGI:1342270 (MGI)
16795 (Entrez Gene)
Gene Tree
VISTA-Point
Chr8 35.08 cM Chr8:72814599-73353540 (-)
GRCm38
Facioscapulohumeral Muscular Dystrophy 1; FSHD1
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 6; MDDGA6
Muscular Dystrophy-Dystroglycanopathy (congenital with Mental Retardation), Type B, 6; MDDGB6
OTTMUSG00000030306 (VEGA)
OTTMUSP00000039267 (VEGA)
OTTMUST00000075036 (VEGA)
chimpanzee LARGE 470192 (Entrez Gene)
Chr22 XP_001154669 (RefSeq)
rhesus macaque LARGE 717403 (Entrez Gene)
Chr10 NP_001247834 (RefSeq)
NM_001260905 (RefSeq)
cattle LARGE 506466 (Entrez Gene)
Chr5 NP_001192517 (RefSeq)
NM_001205588 (RefSeq)
dog LARGE 474521 (Entrez Gene)
Chr10 XP_531751 (RefSeq)
chicken LARGE 418062 (Entrez Gene)
Chr1 Q66PG3 (UniProt | EBI)
NM_001004383 (RefSeq)
western clawed frog LOC100498555 100498555 (Entrez Gene)
ChrUN XP_002943094 (RefSeq)
zebrafish large 446213 (Entrez Gene)
Chr4 Q66PG2 (UniProt | EBI)
NM_001004537 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory