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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
68298

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SOX2 HGNC:11195 (HGNC)
6657 (Entrez Gene)
184429 (OMIM)
Chr3 q26.3-q27 Chr3:181711924-181714436 (+)
GRCh38
Microphthalmia, Syndromic 3; MCOPS3
P48431 (UniProt | EBI)
NM_003106 (RefSeq)
mouse Sox2 MGI:98364 (MGI)
20674 (Entrez Gene)
Gene Tree
VISTA-Point
Chr3 16.93 cM Chr3:34650405-34652461 (+)
GRCm38
OTTMUSG00000021249 (VEGA)
OTTMUSP00000023485 (VEGA)
OTTMUST00000050334 (VEGA)
rat Sox2 499593 (Entrez Gene)
Chr2 q25 NP_001102651 (RefSeq)
NM_001109181 (RefSeq)
chimpanzee SOX2 460869 (Entrez Gene)
Chr3 XP_516895 (RefSeq)
rhesus macaque SOX2 707039 (Entrez Gene)
Chr2 NP_001136412 (RefSeq)
NM_001142940 (RefSeq)
dog SOX2 488092 (Entrez Gene)
Chr34 XP_005639809 (RefSeq)
chicken SOX2 396105 (Entrez Gene)
Chr9 P48430 (UniProt | EBI)
NM_205188 (RefSeq)
western clawed frog sox2 407873 (Entrez Gene)
ChrUN Q6NVN0 (UniProt | EBI)
NM_213704 (RefSeq)
zebrafish sox2 378723 (Entrez Gene)
Chr22 Q6P0E1 (UniProt | EBI)
NM_213118 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory