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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IL4 HGNC:6014 (HGNC)
3565 (Entrez Gene)
147780 (OMIM)
Interleukin 4 (MyGene.info)
HGNC homology
Chr5 q31.1 Chr5:132673986-132682678 (+)
P05112 (UniProt | EBI)
NM_172348 (RefSeq)
mouse Il4 MGI:96556 (MGI)
16189 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 31.97 cM Chr11:53612460-53618665 (-)
atopic dermatitis
Sjogren's syndrome
type 1 diabetes mellitus
16189 (NCBI Gene Model)
P07750 (UniProt | EBI)
NR_027491 (RefSeq)
rat Il4 287287 (Entrez Gene)
Chr10 q22 P20096 (UniProt | EBI)
NM_201270 (RefSeq)
chimpanzee IL4 449565 (Entrez Gene)
Chr5 Q8HYB1 (UniProt | EBI)
NM_001008993 (RefSeq)
cattle IL4 280824 (Entrez Gene)
Chr7 q15-q21 P30367 (UniProt | EBI)
NM_173921 (RefSeq)
dog IL4 403785 (Entrez Gene)
Chr11 O77762 (UniProt | EBI)
NM_001003159 (RefSeq)
macaque, rhesus IL4 574281 (Entrez Gene)
Chr6 P51492 (UniProt | EBI)
NM_001032904 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.13
The Jackson Laboratory