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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
4380

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human WFS1 HGNC:12762 (HGNC)
7466 (Entrez Gene)
606201 (OMIM)
Chr4 p16.1 Chr4:6269850-6303265 (+)
GRCh38
Cataract 41; CTRCT41
Deafness, Autosomal Dominant 6; DFNA6
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Wolfram Syndrome 1; WFS1
Wolfram-Like Syndrome, Autosomal Dominant; WFSL
O76024 (UniProt | EBI)
NM_006005 (RefSeq)
mouse Wfs1 MGI:1328355 (MGI)
22393 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 19.46 cM Chr5:36966104-36988982 (-)
GRCm38
Wolfram Syndrome 1; WFS1
OTTMUSG00000035647 (VEGA)
OTTMUSP00000050236 (VEGA)
OTTMUST00000091241 (VEGA)
rat Wfs1 83725 (Entrez Gene)
Chr14 q21 NP_114011 (RefSeq)
NM_031823 (RefSeq)
chimpanzee WFS1 461100 (Entrez Gene)
Chr4 XP_009445588 (RefSeq)
rhesus macaque WFS1 710948 (Entrez Gene)
Chr5 XP_001092811 (RefSeq)
cattle WFS1 100298456 (Entrez Gene)
Chr6 XP_002688446 (RefSeq)
dog WFS1 482113 (Entrez Gene)
Chr13 XP_539234 (RefSeq)
chicken WFS1 422857 (Entrez Gene)
Chr4 XP_420803 (RefSeq)
western clawed frog wfs1 100127642 (Entrez Gene)
ChrUN NP_001106459 (RefSeq)
NM_001112988 (RefSeq)
zebrafish wfs1b 556580 (Entrez Gene)
Chr14 XP_684510 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory