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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human WFS1 HGNC:12762 (HGNC)
7466 (Entrez Gene)
606201 (OMIM)
HGNC homology
Chr4 p16.1 Chr4:6260368-6303265 (+)
Cataract 41; CTRCT41
Deafness, Autosomal Dominant 6; DFNA6
Diabetes Mellitus, Noninsulin-Dependent; NIDDM
Wolfram-Like Syndrome, Autosomal Dominant; WFSL
Wolfram Syndrome 1; WFS1
O76024 (UniProt | EBI)
NM_001145853 (RefSeq)
mouse Wfs1 MGI:1328355 (MGI)
22393 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 19.46 cM Chr5:36966104-36989205 (-)
Wolfram Syndrome 1; WFS1
OTTMUSG00000035647 (VEGA)
OTTMUSP00000050236 (VEGA)
OTTMUST00000091241 (VEGA)
rat Wfs1 83725 (Entrez Gene)
Chr14 q21 NP_114011 (RefSeq)
NM_031823 (RefSeq)
chimpanzee WFS1 461100 (Entrez Gene)
Chr4 XP_016806742 (RefSeq)
cattle WFS1 100298456 (Entrez Gene)
Chr6 XP_003582394 (RefSeq)
dog WFS1 482113 (Entrez Gene)
Chr13 XP_013974246 (RefSeq)
chicken WFS1 422857 (Entrez Gene)
Chr4 XP_420803 (RefSeq)
zebrafish wfs1b 556580 (Entrez Gene)
Chr14 XP_684510 (RefSeq)
frog, western clawed wfs1 100127642 (Entrez Gene)
Chr1 NP_001106459 (RefSeq)
NM_001112988 (RefSeq)
macaque, rhesus WFS1 710948 (Entrez Gene)
Chr5 XP_014993429 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.07
The Jackson Laboratory