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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
41

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human BRCA2 HGNC:1101 (HGNC)
675 (Entrez Gene)
600185 (OMIM)
Chr13 q12.3 Chr13:32315480-32399672 (+)
GRCh38
Breast Cancer
Breast-Ovarian Cancer, Familial, Susceptibility to, 2; BROVCA2
Fanconi Anemia, Complementation Group D1; FANCD1
Glioma Susceptibility 3; GLM3
Medulloblastoma; MDB
Pancreatic Cancer, Susceptibility to, 2
Prostate Cancer
Wilms Tumor 1; WT1
P51587 (UniProt | EBI)
NM_000059 (RefSeq)
mouse Brca2 MGI:109337 (MGI)
12190 (Entrez Gene)
Gene Tree
VISTA-Point
Chr5 89.52 cM Chr5:150522630-150569746 (+)
GRCm38
Breast Cancer
Fanconi Anemia, Complementation Group D1; FANCD1
Medulloblastoma; MDB
Pancreatic Cancer
Prostate Cancer
ENSMUSG00000041147 (Ensembl Gene Model)
ENSMUSP00000038576 (Ensembl)
ENSMUST00000044620 (Ensembl)
rat Brca2 360254 (Entrez Gene)
Chr12 p12 O35923 (UniProt | EBI)
NM_031542 (RefSeq)
chimpanzee BRCA2 452526 (Entrez Gene)
Chr13 XP_509619 (RefSeq)
rhesus macaque BRCA2 721981 (Entrez Gene)
Chr17 XP_001118184 (RefSeq)
cattle BRCA2 507069 (Entrez Gene)
Chr12 XP_002684323 (RefSeq)
dog BRCA2 474180 (Entrez Gene)
Chr25 NP_001006654 (RefSeq)
NM_001006653 (RefSeq)
chicken BRCA2 374139 (Entrez Gene)
Chr1 NP_989607 (RefSeq)
NM_204276 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory