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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human BRCA2 HGNC:1101 (HGNC)
675 (Entrez Gene)
600185 (OMIM)
BRCA2 (MyGene.info)
HGNC homology
Chr13 q13.1 Chr13:32315480-32399672 (+)
breast cancer
esophageal atresia/tracheoesophageal fistula
Fanconi anemia complementation group D1
hereditary breast ovarian cancer syndrome
malignant glioma
pancreatic cancer
prostate cancer
P51587 (UniProt | EBI)
NM_000059 (RefSeq)
mouse Brca2 MGI:109337 (MGI)
12190 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 89.52 cM Chr5:150522630-150570329 (+)
breast cancer
Fanconi anemia complementation group D1
OTTMUSG00000055512 (VEGA)
OTTMUSP00000072371 (VEGA)
OTTMUST00000137399 (VEGA)
rat Brca2 360254 (Entrez Gene)
Chr12 p12 O35923 (UniProt | EBI)
NM_031542 (RefSeq)
chimpanzee BRCA2 452526 (Entrez Gene)
Chr13 XP_016780623 (RefSeq)
cattle BRCA2 507069 (Entrez Gene)
Chr12 XP_010809072 (RefSeq)
dog BRCA2 474180 (Entrez Gene)
Chr25 NP_001006654 (RefSeq)
NM_001006653 (RefSeq)
chicken BRCA2 374139 (Entrez Gene)
Chr1 NP_989607 (RefSeq)
NM_204276 (RefSeq)
macaque, rhesus BRCA2 721981 (Entrez Gene)
Chr17 XP_014976325 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory