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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human BEST1 HGNC:12703 (HGNC)
7439 (Entrez Gene)
607854 (OMIM)
Bestrophin 1 (MyGene.info)
HGNC homology
Chr11 q12.3 Chr11:61946722-61964465 (+)
retinitis pigmentosa 50
vitelliform macular dystrophy
O76090 (UniProt | EBI)
NM_004183 (RefSeq)
mouse Best1 MGI:1346332 (MGI)
24115 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 6.24 cM Chr19:9985174-10001633 (-)
vitelliform macular dystrophy
OTTMUSG00000028256 (VEGA)
OTTMUSP00000035635 (VEGA)
OTTMUST00000070017 (VEGA)
rat Best1 293735 (Entrez Gene)
Chr1 q43 NP_001011940 (RefSeq)
NM_001011940 (RefSeq)
chimpanzee BEST1 466630 (Entrez Gene)
Chr11 XP_009421533 (RefSeq)
cattle BEST1 508924 (Entrez Gene)
Chr29 NP_001073714 (RefSeq)
NM_001080245 (RefSeq)
dog BEST1 483791 (Entrez Gene)
Chr18 NP_001091014 (RefSeq)
NM_001097545 (RefSeq)
chicken BEST1 423124 (Entrez Gene)
Chr5 XP_421055 (RefSeq)
zebrafish best1 560608 (Entrez Gene)
Chr25 XP_009295979 (RefSeq)
frog, western clawed best1 100302038 (Entrez Gene)
Chr4 NP_001155223 (RefSeq)
NM_001161751 (RefSeq)
macaque, rhesus BEST1 718993 (Entrez Gene)
Chr14 XP_014969469 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory