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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ARHGEF6 HGNC:685 (HGNC)
9459 (Entrez Gene)
300267 (OMIM)
ARHGEF6 (MyGene.info)
HGNC homology
ChrX q26.3 ChrX:136665547-136781656 (-)
non-syndromic X-linked intellectual disability
Q15052 (UniProt | EBI)
NM_001306177 (RefSeq)
mouse Arhgef6 MGI:1920591 (MGI)
73341 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 31.26 cM ChrX:57231485-57338729 (-)
OTTMUSG00000017820 (VEGA)
OTTMUSP00000019411 (VEGA)
OTTMUST00000043148 (VEGA)
rat Arhgef6 363509 (Entrez Gene)
ChrX q37 Q5XXR3 (UniProt | EBI)
NM_001005565 (RefSeq)
chimpanzee ARHGEF6 473803 (Entrez Gene)
ChrX XP_016799765 (RefSeq)
cattle ARHGEF6 533823 (Entrez Gene)
ChrX NP_001179929 (RefSeq)
NM_001193000 (RefSeq)
dog ARHGEF6 610290 (Entrez Gene)
ChrX XP_852793 (RefSeq)
chicken ARHGEF6 422247 (Entrez Gene)
Chr4 Q5ZLR6 (UniProt | EBI)
NM_001006432 (RefSeq)
zebrafish arhgef6 558288 (Entrez Gene)
Chr14 XP_005173279 (RefSeq)
frog, western clawed arhgef6 100489192 (Entrez Gene)
Chr8 XP_012825042 (RefSeq)
macaque, rhesus ARHGEF6 693976 (Entrez Gene)
ChrX NP_001253502 (RefSeq)
NM_001266573 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory