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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TPP1 HGNC:2073 (HGNC)
1200 (Entrez Gene)
607998 (OMIM)
Tripeptidyl peptidase I (MyGene.info)
HGNC homology
Chr11 p15.4 Chr11:6612766-6619461 (-)
neuronal ceroid lipofuscinosis 2
O14773 (UniProt | EBI)
NM_000391 (RefSeq)
mouse Tpp1 MGI:1336194 (MGI)
12751 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 55.97 cM Chr7:105744811-105752235 (-)
neuronal ceroid lipofuscinosis 2
OTTMUSG00000060349 (VEGA)
OTTMUSP00000076833 (VEGA)
OTTMUST00000147669 (VEGA)
rat Tpp1 83534 (Entrez Gene)
Chr1 q32 Q9EQV6 (UniProt | EBI)
NM_031357 (RefSeq)
chimpanzee TPP1 450999 (Entrez Gene)
Chr11 Q5IS74 (UniProt | EBI)
NM_001013007 (RefSeq)
cattle TPP1 515575 (Entrez Gene)
Chr15 Q0V8B6 (UniProt | EBI)
NM_001075718 (RefSeq)
dog TPP1 485337 (Entrez Gene)
Chr21 Q9XSB8 (UniProt | EBI)
NM_001013847 (RefSeq)
chicken TPP1 425576 (Entrez Gene)
Chr1 XP_015136410 (RefSeq)
zebrafish tpp1 798347 (Entrez Gene)
Chr17 NP_001122270 (RefSeq)
NM_001128798 (RefSeq)
frog, western clawed tpp1 100124868 (Entrez Gene)
ChrUN NP_001096294 (RefSeq)
NM_001102824 (RefSeq)
macaque, rhesus TPP1 709838 (Entrez Gene)
Chr14 XP_001108748 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory