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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
317

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TTR HGNC:12405 (HGNC)
7276 (Entrez Gene)
176300 (OMIM)
Chr18 q12.1 Chr18:31591767-31599024 (+)
GRCh38
Amyloidosis, Hereditary, Transthyretin-Related
Carpal Tunnel Syndrome; CTS1
Hyperthyroxinemia, Dystransthyretinemic; DTTRH
P02766 (UniProt | EBI)
NM_000371 (RefSeq)
mouse Ttr MGI:98865 (MGI)
22139 (Entrez Gene)
Gene Tree
VISTA-Point
Chr18 11.47 cM Chr18:20665250-20674324 (+)
GRCm38
ENSMUSG00000061808 (Ensembl Gene Model)
ENSMUSP00000074783 (Ensembl)
ENSMUST00000075312 (Ensembl)
rat Ttr 24856 (Entrez Gene)
Chr18 p P02767 (UniProt | EBI)
NM_012681 (RefSeq)
chimpanzee TTR 493188 (Entrez Gene)
Chr18 Q5U7I5 (UniProt | EBI)
NM_001009137 (RefSeq)
rhesus macaque TTR 705943 (Entrez Gene)
Chr18 NP_001248608 (RefSeq)
NM_001261679 (RefSeq)
cattle TTR 280948 (Entrez Gene)
Chr24 O46375 (UniProt | EBI)
NM_173967 (RefSeq)
dog TTR 480167 (Entrez Gene)
Chr7 XP_537290 (RefSeq)
chicken TTR 396277 (Entrez Gene)
Chr2 P27731 (UniProt | EBI)
NM_205335 (RefSeq)
western clawed frog ttr 100125183 (Entrez Gene)
ChrUN A4QNN7 (UniProt | EBI)
NM_001103069 (RefSeq)
zebrafish ttr 449556 (Entrez Gene)
Chr20 NP_001005598 (RefSeq)
NM_001005598 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory