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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PAPPA HGNC:8602 (HGNC)
5069 (Entrez Gene)
176385 (OMIM)
HGNC homology
Chr9 q33.1 Chr9:116153752-116402321 (+)
Q13219 (UniProt | EBI)
NM_002581 (RefSeq)
mouse Pappa MGI:97479 (MGI)
18491 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 34.14 cM Chr4:65124174-65357509 (+)
ENSMUSG00000028370 (Ensembl Gene Model)
ENSMUSP00000081545 (Ensembl)
ENSMUST00000084501 (Ensembl)
rat Pappa1 313262 (Entrez Gene)
Chr5 q24 NP_001101409 (RefSeq)
NM_001107939 (RefSeq)
chimpanzee PAPPA 464690 (Entrez Gene)
Chr9 XP_016817028 (RefSeq)
cattle PAPPA 282647 (Entrez Gene)
Chr8 XP_024852122 (RefSeq)
dog PAPPA 481692 (Entrez Gene)
Chr11 XP_022280739 (RefSeq)
chicken PAPPA 417245 (Entrez Gene)
Chr17 XP_025011867 (RefSeq)
zebrafish pappaa 101448000 (Entrez Gene)
Chr5 NP_001265734 (RefSeq)
NM_001278805 (RefSeq)
pappab 101448001 (Entrez Gene)
Chr5 NP_001265737 (RefSeq)
NM_001278808 (RefSeq)
frog, western clawed pappa 100495014 (Entrez Gene)
Chr8 XP_002935250 (RefSeq)
macaque, rhesus PAPPA 706783 (Entrez Gene)
Chr15 XP_014972456 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory