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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SNCA HGNC:11138 (HGNC)
6622 (Entrez Gene)
163890 (OMIM)
Alpha-synuclein (MyGene.info)
HGNC homology
Chr4 q22.1 Chr4:89724099-89838324 (-)
autosomal dominant Parkinson's disease 1
autosomal dominant Parkinson's disease 4
Lewy body dementia
P37840 (UniProt | EBI)
NM_007308 (RefSeq)
mouse Snca MGI:1277151 (MGI)
20617 (Entrez Gene)
Gene Tree
HGNC homology
Chr6 29.15 cM Chr6:60731575-60829855 (-)
autosomal dominant Parkinson's disease 1
autosomal dominant Parkinson's disease 4
OTTMUSG00000057624 (VEGA)
OTTMUSP00000073978 (VEGA)
OTTMUST00000141608 (VEGA)
rat Snca 29219 (Entrez Gene)
Chr4 q24 P37377 (UniProt | EBI)
NM_019169 (RefSeq)
chimpanzee SNCA 461375 (Entrez Gene)
Chr4 P61145 (UniProt | EBI)
NM_001009158 (RefSeq)
cattle SNCA 282857 (Entrez Gene)
Chr6 Q3T0G8 (UniProt | EBI)
NM_001034041 (RefSeq)
dog SNCA 478478 (Entrez Gene)
Chr32 XP_022269246 (RefSeq)
chicken SNCA 395393 (Entrez Gene)
Chr4 NP_990004 (RefSeq)
NM_204673 (RefSeq)
frog, western clawed snca 100038302 (Entrez Gene)
Chr1 NP_001090876 (RefSeq)
NM_001097407 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory