Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gnrh1  gonadotropin releasing hormone 1   (Synonyms: LHRH, LNRH)
Results	Reference
1	J:321502 Camera M, Russo I, Zamboni V, Ammoni A, Rando S, Morellato A, Cimino I, Angelini C, Giacobini P, Oleari R, Amoruso F, Cariboni A, Franceschini I, Turco E, Defilippi P, Merlo GR, p140Cap Controls Female Fertility in Mice Acting via Glutamatergic Afference on Hypothalamic Gonadotropin-Releasing Hormone Neurons. Front Neurosci. 2022;16:744693
1	J:268511 Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M, Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Cell Rep. 2018 Jul 3;24(1):79-94
1	J:39356 Good DJ, Porter FD, Mahon KA, Parlow AF, Westphal H, Kirsch IR, Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet. 1997 Apr;15(4):397-401
1	J:285939 Hoffmann HM, Larder R, Lee JS, Hu RJ, Trang C, Devries BM, Clark DD, Mellon PL, Differential CRE Expression in Lhrh-cre and GnRH-cre Alleles and the Impact on Fertility in Otx2-Flox Mice. Neuroendocrinology. 2019;108(4):328-342
1	J:333827 Huang C, Zhao S, Yang Y, Guo T, Ke H, Mi X, Qin Y, Chen ZJ, Zhao S, TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis. J Clin Invest. 2023 Mar 1;133(5)
1	J:257035 Kim YJ, Osborn DP, Lee JY, Araki M, Araki K, Mohun T, Kansakoski J, Brandstack N, Kim HT, Miralles F, Kim CH, Brown NA, Kim HG, Martinez-Barbera JP, Ataliotis P, Raivio T, Layman LC, Kim SH, WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome. EMBO Rep. 2018 Feb;19(2):269-289
1	J:168233 Larder R, Clark DD, Miller NL, Mellon PL, Hypothalamic dysregulation and infertility in mice lacking the homeodomain protein Six6. J Neurosci. 2011 Jan 12;31(2):426-38
1	J:174086 Layman WS, Hurd EA, Martin DM, Reproductive dysfunction and decreased GnRH neurogenesis in a mouse model of CHARGE syndrome. Hum Mol Genet. 2011 Aug 15;20(16):3138-50
1*	J:107587 Matsumoto S, Yamazaki C, Masumoto KH, Nagano M, Naito M, Soga T, Hiyama H, Matsumoto M, Takasaki J, Kamohara M, Matsuo A, Ishii H, Kobori M, Katoh M, Matsushime H, Furuichi K, Shigeyoshi Y, Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4140-5
1	J:308864 Rotgers E, Nicol B, Rodriguez K, Rattan S, Flaws JA, Yao HH, Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice. FASEB J. 2021 Aug;35(8):e21770
1	J:276971 Saadi H, Shan Y, Marazziti D, Wray S, GPR37 Signaling Modulates Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Cells in Mice. Front Cell Neurosci. 2019;13:200
1*	J:233793 Taylor-Burds C, Cheng P, Wray S, Chloride Accumulators NKCC1 and AE2 in Mouse GnRH Neurons: Implications for GABAA Mediated Excitation. PLoS One. 2015;10(6):e0131076
1*	J:125764 Tiong J, Locastro T, Wray S, Gonadotropin-releasing hormone-1 (GnRH-1) is involved in tooth maturation and biomineralization. Dev Dyn. 2007 Nov;236(11):2980-92
1*	J:207824 Tiong JD, Pakiam JG, Wray S, Gonadotropin releasing hormone-1 expression in incisors of mice. Endocrinology. 2004 Aug;145(8):3608-12
1	J:101090 Toba Y, Pakiam JG, Wray S, Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse. Eur J Neurosci. 2005 Jul;22(1):79-92
1	J:242190 Vastagh C, Schwirtlich M, Kwakowsky A, Erdelyi F, Margolis FL, Yanagawa Y, Katarova Z, Szabo G, The spatiotemporal segregation of GAD forms defines distinct GABA signaling functions in the developing mouse olfactory system and provides novel insights into the origin and migration of GnRH neurons. Dev Neurobiol. 2015 Mar;75(3):249-70