Assay
Age
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RT-PCR
Postnatal
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Crx cone-rod homeobox (Synonyms: Crx1) | |
Results | Reference |
1* | J:98077 Alfano G, Vitiello C, Caccioppoli C, Caramico T, Carola A, Szego MJ, McInnes RR, Auricchio A, Banfi S, Natural antisense transcripts associated with genes involved in eye development. Hum Mol Genet. 2005 Apr 1;14(7):913-23 |
1* | J:70841 Bibb LC, Holt JK, Tarttelin EE, Hodges MD, Gregory-Evans K, Rutherford A, Lucas RJ, Sowden JC, Gregory-Evans CY, Temporal and spatial expression patterns of the CRX transcription factor and its downstream targets. Critical differences during human and mouse eye development. Hum Mol Genet. 2001 Jul 15;10(15):1571-9 |
1 | J:278101 Brightman DS, Grant RL, Ruzycki PA, Suzuki R, Hennig AK, Chen S, MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity. Sci Rep. 2018 Aug 9;8(1):11902 |
1* | J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85 |
1 | J:153683 Jia L, Oh EC, Ng L, Srinivas M, Brooks M, Swaroop A, Forrest D, Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17534-9 |
1 | J:160529 Katoh K, Omori Y, Onishi A, Sato S, Kondo M, Furukawa T, Blimp1 suppresses Chx10 expression in differentiating retinal photoreceptor precursors to ensure proper photoreceptor development. J Neurosci. 2010 May 12;30(19):6515-26 |
1 | J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:301112 Maddala R, Gao J, Mathias RT, Lewis TR, Arshavsky VY, Levine A, Backer JM, Bresnick AR, Rao PV, Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract. Sci Rep. 2021 Jan 26;11(1):2203 |
1 | J:119192 Ozawa Y, Nakao K, Shimazaki T, Shimmura S, Kurihara T, Ishida S, Yoshimura A, Tsubota K, Okano H, SOCS3 is required to temporally fine-tune photoreceptor cell differentiation. Dev Biol. 2007 Mar 15;303(2):591-600 |
1 | J:303303 Pan M, Yin Y, Wang X, Wang Q, Zhang L, Hu H, Wang C, Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16 |
1 | J:186563 Prasov L, Glaser T, Pushing the envelope of retinal ganglion cell genesis: Context dependent function of Math5 (Atoh7). Dev Biol. 2012 Aug 15;368(2):214-30 |
1 | J:87739 Rutherford AD, Dhomen N, Smith HK, Sowden JC, Delayed expression of the Crx gene and photoreceptor development in the Chx10-deficient retina. Invest Ophthalmol Vis Sci. 2004 Feb;45(2):375-84 |
1 | J:179784 Sanuki R, Onishi A, Koike C, Muramatsu R, Watanabe S, Muranishi Y, Irie S, Uneo S, Koyasu T, Matsui R, Cherasse Y, Urade Y, Watanabe D, Kondo M, Yamashita T, Furukawa T, miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. Nat Neurosci. 2011 Sep;14(9):1125-34 |
1 | J:216471 Sapkota D, Chintala H, Wu F, Fliesler SJ, Hu Z, Mu X, Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development. Proc Natl Acad Sci U S A. 2014 Sep 30;111(39):E4086-95 |
1 | J:274446 Wei W, Liu B, Jiang H, Jin K, Xiang M, Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Mol Neurobiol. 2019 Mar;56(3):1719-1736 |
1* | J:279788 Wen B, Li S, Li H, Chen Y, Ma X, Wang J, Lu F, Qu J, Hou L, Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium. Sci Rep. 2016 Feb 15;6:21208 |
1* | J:71938 Wu Y, Cutting GR, Developmentally regulated expression of GABA receptor rho1 and rho2 subunits, L7 and cone-rod homeobox (CRX) genes in mouse retina. Brain Res. 2001 Aug 31;912(1):1-8 |
1 | J:287680 Yamamoto H, Kon T, Omori Y, Furukawa T, Functional and Evolutionary Diversification of Otx2 and Crx in Vertebrate Retinal Photoreceptor and Bipolar Cell Development. Cell Rep. 2020 Jan 21;30(3):658-671.e5 |
1 | J:243794 Yan N, Cheng L, Cho K, Malik MT, Xiao L, Guo C, Yu H, Zhu R, Rao RC, Chen DF, Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1. Sci Rep. 2016 Sep 28;6:33887 |
1 | J:339443 Zocchi L, Mehta A, Wu SC, Wu J, Gu Y, Wang J, Suh S, Spitale RC, Benavente CA, Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression. Oncogenesis. 2020 Feb 18;9(2):25 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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