About   Help   FAQ
Gene Expression Literature Summary
Assay
Age
RT-PCR
Adult

26 matching records from 26 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Pdx1  pancreatic and duodenal homeobox 1   (Synonyms: IDX-1, Ipf1, IPF-1, Mody4, pdx-1, STF-1)
Results  Reference
1J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62
1J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8
1J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32
1J:184887 Du A, McCracken KW, Walp ER, Terry NA, Klein TJ, Han A, Wells JM, May CL, Arx is required for normal enteroendocrine cell development in mice and humans. Dev Biol. 2012 May 1;365(1):175-88
1J:141800 Edfalk S, Steneberg P, Edlund H, Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion. Diabetes. 2008 Sep;57(9):2280-7
1J:89720 Fajas L, Annicotte JS, Miard S, Sarruf D, Watanabe M, Auwerx J, Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice. J Clin Invest. 2004 May;113(9):1288-95
1*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:129765 Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H, BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab. 2007 Mar;5(3):207-19
1*J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1J:194010 Iglesias J, Barg S, Vallois D, Lahiri S, Roger C, Yessoufou A, Pradevand S, McDonald A, Bonal C, Reimann F, Gribble F, Debril MB, Metzger D, Chambon P, Herrera P, Rutter GA, Prentki M, Thorens B, Wahli W, PPARbeta/delta affects pancreatic beta cell mass and insulin secretion in mice. J Clin Invest. 2012 Nov 1;122(11):4105-17
1*J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12
1J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79
1J:51571 Krapp A, Knofler M, Ledermann B, Burki K, Berney C, Zoerkler N, Hagenbuchle O, Wellauer PK, The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev. 1998 Dec 1;12(23):3752-63
1J:94589 Lamotte L, Jackerott M, Bucchini D, Jami J, Joshi RL, Deltour L, Knock-in of diphteria toxin A chain gene at Ins2 locus: effects on islet development and localization of Ins2 expression in the brain. Transgenic Res. 2004 Oct;13(5):463-73
1J:164411 Lau J, Hebrok M, Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function. Diabetes. 2010 May;59(5):1211-21
1J:178173 Mastracci TL, Wilcox CL, Arnes L, Panea C, Golden JA, May CL, Sussel L, Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
1J:200656 Mead TJ, Wang Q, Bhattaram P, Dy P, Afelik S, Jensen J, Lefebvre V, A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration. Nucleic Acids Res. 2013 Apr;41(8):4459-69
1J:177060 Medina MC, Molina J, Gadea Y, Fachado A, Murillo M, Simovic G, Pileggi A, Hernandez A, Edlund H, Bianco AC, The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human {beta}-Cells and Its Targeted Inactivation Impairs Insulin Secretion. Endocrinology. 2011 Oct;152(10):3717-27
1J:208938 Reinert RB, Brissova M, Shostak A, Pan FC, Poffenberger G, Cai Q, Hundemer GL, Kantz J, Thompson CS, Dai C, McGuinness OP, Powers AC, Vascular endothelial growth factor-a and islet vascularization are necessary in developing, but not adult, pancreatic islets. Diabetes. 2013 Dec;62(12):4154-64
1J:99302 Rosanas-Urgell A, Marfany G, Garcia-Fernandez J, Pdx1-related homeodomain transcription factors are distinctly expressed in mouse adult pancreatic islets. Mol Cell Endocrinol. 2005 Jun 15;237(1-2):59-66
1J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7
1J:164654 Valtat B, Dupuis C, Zenaty D, Singh-Estivalet A, Tronche F, Breant B, Blondeau B, Genetic evidence of the programming of beta cell mass and function by glucocorticoids in mice. Diabetologia. 2010 Sep 21;
1J:129652 Vuguin PM, Kedees MH, Cui L, Guz Y, Gelling RW, Nejathaim M, Charron MJ, Teitelman G, Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology. 2006 Sep;147(9):3995-4006
1J:132695 Wilding Crawford L, Tweedie Ables E, Oh YA, Boone B, Levy S, Gannon M, Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis. PLoS ONE. 2008;3(2):e1611
1J:174673 Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV, Context-specific {alpha}-to-{beta}-cell reprogramming by forced Pdx1 expression. Genes Dev. 2011 Aug 15;25(16):1680-5
1J:87724 Yoshitomi H, Zaret KS, Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development. 2004 Feb;131(4):807-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2014
MGI 5.20
The Jackson Laboratory