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Gene Expression Literature Summary
Assay
Age
In situ protein (section)
Adult

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
Pcsk1  proprotein convertase subtilisin/kexin type 1   (Synonyms: Nec1, Nec-1, PC1, PC3, Phpp-1, prohormone convertase 1/3, SPC3)
Results  Reference
1J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92
1J:35634 Marcinkiewicz M, Day R, Seidah NG, Chretien M, Ontogeny of the prohormone convertases PC1 and PC2 in the mouse hypophysis and their colocalization with corticotropin and alpha-melanotropin. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4922-6
1J:20976 Marcinkiewicz M, Ramla D, Seidah NG, Chretien M, Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets. Endocrinology. 1994 Oct;135(4):1651-60
1J:187963 Talchai C, Xuan S, Lin HV, Sussel L, Accili D, Pancreatic beta Cell Dedifferentiation as a Mechanism of Diabetic beta Cell Failure. Cell. 2012 Sep 14;150(6):1223-34
1J:85590 Vincent M, Guz Y, Rozenberg M, Webb G, Furuta M, Steiner D, Teitelman G, Abrogation of protein convertase 2 activity results in delayed islet cell differentiation and maturation, increased alpha-cell proliferation, and islet neogenesis. Endocrinology. 2003 Sep;144(9):4061-9
1J:129652 Vuguin PM, Kedees MH, Cui L, Guz Y, Gelling RW, Nejathaim M, Charron MJ, Teitelman G, Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation. Endocrinology. 2006 Sep;147(9):3995-4006
1J:77320 Wilson ME, Kalamaras JA, German MS, Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas. Mech Dev. 2002 Jul;115(1-2):171-6

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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory