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Gene Expression Literature Summary
Assay
Age
RT-PCR
9.5 DPC

6 matching records from 6 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Wnt2  wingless-type MMTV integration site family, member 2   (Synonyms: 2610510E18Rik, Int1l1, Irp, m-irp, Mirp, Wnt-2, Wnt2a)
Results  Reference
1J:261899 Hasten E, McDonald-McGinn DM, Crowley TB, Zackai E, Emanuel BS, Morrow BE, Racedo SE, Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome. Hum Mol Genet. 2018 Jun 1;27(11):1847-1857
1J:186421 Klaus A, Muller M, Schulz H, Saga Y, Martin JF, Birchmeier W, Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10921-6
1J:242314 Racedo SE, Hasten E, Lin M, Devakanmalai GS, Guo T, Ozbudak EM, Cai CL, Zheng D, Morrow BE, Reduced dosage of beta-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome. PLoS Genet. 2017 Mar;13(3):e1006687
1J:344102 Racedo SE, Liu Y, Shi L, Zheng D, Morrow BE, Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals. Dev Biol. 2024 Feb;506:72-84
1J:267472 Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, Horb ME, Luna-Zurita L, Ho RK, Kyba M, Jensen B, Zorn AM, Conlon FL, Moskowitz IP, Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10615-E10624
1*J:229467 Zhang KK, Xiang M, Zhou L, Liu J, Curry N, Heine Suner D, Garcia-Pavia P, Zhang X, Wang Q, Xie L, Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation. Hum Mol Genet. 2016 Mar 15;25(6):1140-51

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory