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Gene Expression Literature Summary
Assay
Age
RT-PCR
9.5 DPC

22 matching records from 22 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Igf2  insulin-like growth factor 2   (Synonyms: Igf-2, Igf-II, M6pr, Mpr, Peg2)
Results  Reference
1J:106778 Arnaud P, Hata K, Kaneda M, Li E, Sasaki H, Feil R, Kelsey G, Stochastic imprinting in the progeny of Dnmt3L-/- females. Hum Mol Genet. 2006 Feb 15;15(4):589-98
1J:186116 Church DN, Phillips BR, Stuckey DJ, Barnes DJ, Buffa FM, Manek S, Clarke K, Harris AL, Carter EJ, Hassan AB, Igf2 ligand dependency of Pten(+/-) developmental and tumour phenotypes in the mouse. Oncogene. 2012 Aug 2;31(31):3635-46
1*J:767 Hannon K, Smith CK 2nd, Bales KR, Santerre RF, Temporal and quantitative analysis of myogenic regulatory and growth factor gene expression in the developing mouse embryo. Dev Biol. 1992 May;151(1):137-44
1*J:192195 Himes KP, Koppes E, Chaillet JR, Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth. Dev Biol. 2013 Jan 1;373(1):72-82
1*J:68455 Howell CY, Bestor TH, Ding F, Latham KE, Mertineit C, Trasler JM, Chaillet JR, Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell. 2001 Mar 23;104(6):829-38
1J:173801 Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP, Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol. 2011 May 15;353(2):420-31
1*J:28395 Kaneko-Ishino T, Kuroiwa Y, Miyoshi N, Kohda T, Suzuki R, Yokoyama M, Viville S, Barton SC, Ishino F, Surani MA, Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization. Nat Genet. 1995 Sep;11(1):52-9
1*J:182357 Kobayashi H, Sakurai T, Sato S, Nakabayashi K, Hata K, Kono T, Imprinted DNA methylation reprogramming during early mouse embryogenesis at the Gpr1-Zdbf2 locus is linked to long cis-intergenic transcription. FEBS Lett. 2012 Mar 23;586(6):827-33
1J:171220 Li P, Cavallero S, Gu Y, Chen TH, Hughes J, Hassan AB, Bruning JC, Pashmforoush M, Sucov HM, IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development. Development. 2011 May;138(9):1795-805
1*J:147318 Lopez-Garcia C, Lopez-Contreras AJ, Cremades A, Castells MT, Marin F, Schreiber F, Penafiel R, Molecular and morphological changes in placenta and embryo development associated with the inhibition of polyamine synthesis during midpregnancy in mice. Endocrinology. 2008 Oct;149(10):5012-23
1*J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461
1*J:47783 Obata Y, Kaneko-Ishino T, Koide T, Takai Y, Ueda T, Domeki I , Shiroishi T , Ishino F , Kono T, Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development. 1998 Apr;125(8):1553-60
1J:112969 Ogawa H, Wu Q, Komiyama J, Obata Y, Kono T, Disruption of parental-specific expression of imprinted genes in uniparental fetuses. FEBS Lett. 2006 Oct 2;580(22):5377-84
1J:130399 Oh R, Ho R, Mar L, Gertsenstein M, Paderova J, Hsien J, Squire JA, Higgins MJ, Nagy A, Lefebvre L, Epigenetic and phenotypic consequences of a truncation disrupting the imprinted domain on distal mouse chromosome 7. Mol Cell Biol. 2008 Feb;28(3):1092-103
1J:170637 Oh-McGinnis R, Bogutz AB, Lefebvre L, Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction. Dev Biol. 2011 Mar 15;351(2):277-86
1J:106104 Rostam Zadehl J, Penkov LI, Klimov EA, Platonov ES, Sulimova GE, TGFalpha reactivates imprinted Igf2 in the parthenogenetic mice embryos and placenta. Genetika. 2005 Oct;41(10):1387-91
1*J:42929 Shemer R, Birger Y, Riggs AD, Razin A, Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10267-72
1J:129049 Takebayashi S, Tamura T, Matsuoka C, Okano M, Major and essential role for the DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions. Mol Cell Biol. 2007 Dec;27(23):8243-58
1*J:10840 Telford NA, Hogan A, Franz CR, Schultz GA, Expression of genes for insulin and insulin-like growth factors and receptors in early postimplantation mouse embryos and embryonal carcinoma cells. Mol Reprod Dev. 1990 Oct;27(2):81-92
1J:105567 Thorvaldsen JL, Fedoriw AM, Nguyen S, Bartolomei MS, Developmental profile of H19 differentially methylated domain (DMD) deletion alleles reveals multiple roles of the DMD in regulating allelic expression and DNA methylation at the imprinted H19/Igf2 locus. Mol Cell Biol. 2006 Feb;26(4):1245-58
1*J:130398 Wagschal A, Sutherland HG, Woodfine K, Henckel A, Chebli K, Schulz R, Oakey RJ, Bickmore WA, Feil R, G9a histone methyltransferase contributes to imprinting in the mouse placenta. Mol Cell Biol. 2008 Feb;28(3):1104-13
1J:310855 Yiu JHC, Cheung SWM, Cai J, Chan KS, Chen J, Cheong LY, Chau HT, Xu A, Li RHW, Woo CW, TLR5 Supports Development of Placental Labyrinthine Zone in Mice. Front Cell Dev Biol. 2021;9:711253

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory