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Gene Expression Literature Summary
Assay
Age
In situ protein (whole mount)
9.5 DPC

7 matching records from 7 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
En2  engrailed 2   (Synonyms: En-2)
Results  Reference
1J:24349 Chen ZF, Behringer RR, twist is required in head mesenchyme for cranial neural tube morphogenesis. Genes Dev. 1995 Mar 15;9(6):686-99
1J:35491 Danielian PS, McMahon AP, Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature. 1996 Sep 26;383(6598):332-4
1J:31181 Davis CA, Holmyard DP, Millen KJ, Joyner AL, Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development. 1991 Feb;111(2):287-98
1J:971 McMahon AP, Joyner AL, Bradley A, McMahon JA, The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell. 1992 May 15;69(4):581-95
1J:27770 Sadler TW, Liu ET, Augustine KA, Antisense targeting of engrailed-1 causes abnormal axis formation in mouse embryos. Teratology. 1995 May;51(5):292-9
1J:95392 Simon HH, Scholz C, O'Leary DD, Engrailed genes control developmental fate of serotonergic and noradrenergic neurons in mid- and hindbrain in a gene dose-dependent manner. Mol Cell Neurosci. 2005 Jan;28(1):96-105
1*J:19212 Wurst W, Auerbach AB, Joyner AL, Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development. 1994 Jul;120(7):2065-75

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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory