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Gene Expression Literature Summary
Assay
Age
In situ protein (section)
9.5 DPC

55 matching records from 55 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Acta2  actin, alpha 2, smooth muscle, aorta   (Synonyms: 0610041G09Rik, Actvs, alphaSMA, a-SMA, SMalphaA)
Results  Reference
1J:126737 Astrof S, Crowley D, Hynes RO, Multiple cardiovascular defects caused by the absence of alternatively spliced segments of fibronectin. Dev Biol. 2007 Nov 1;311(1):11-24
1J:128915 Beliakoff J, Lee J, Ueno H, Aiyer A, Weissman IL, Barsh GS, Cardiff RD, Sun Z, The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development. Mol Cell Biol. 2008 Jan;28(1):282-92
1*J:73775 Byrd N, Becker S, Maye P, Narasimhaiah R, St-Jacques B, Zhang X, McMahon J, McMahon A, Grabel L, Hedgehog is required for murine yolk sac angiogenesis. Development. 2002 Jan;129(2):361-72
1J:98373 Carvalho RL, Jonker L, Goumans MJ, Larsson J, Bouwman P, Karlsson S, Dijke PT, Arthur HM, Mummery CL, Defective paracrine signalling by TGFbeta in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development. 2004 Dec;131(24):6237-47
1J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40
1J:169957 Chen L, Fulcoli FG, Tang S, Baldini A, Tbx1 regulates proliferation and differentiation of multipotent heart progenitors. Circ Res. 2009 Oct 23;105(9):842-51
1J:102537 Compernolle V, Brusselmans K, Franco D, Moorman A, Dewerchin M, Collen D, Carmeliet P, Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha. Cardiovasc Res. 2003 Dec 1;60(3):569-79
1J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14
1J:169692 Copeland JN, Feng Y, Neradugomma NK, Fields PE, Vivian JL, Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac. BMC Dev Biol. 2011;11:12
1J:80720 Costell M, Carmona R, Gustafsson E, Gonzalez-Iriarte M, Fassler R, Munoz-Chapuli R, Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice. Circ Res. 2002 Jul 26;91(2):158-64
1J:174085 Cunningham K, Uchida Y, O'Donnell E, Claudio E, Li W, Soneji K, Wang H, Mukouyama YS, Siebenlist U, Conditional deletion of Ccm2 causes hemorrhage in the adult brain: a mouse model of human cerebral cavernous malformations. Hum Mol Genet. 2011 Aug 15;20(16):3198-206
1J:178290 del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Perez-Pomares JM, de la Pompa JL, Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis. Circ Res. 2011 Apr 1;108(7):824-36
1J:159118 Fotopoulou S, Oikonomou N, Grigorieva E, Nikitopoulou I, Paparountas T, Thanassopoulou A, Zhao Z, Xu Y, Kontoyiannis DL, Remboutsika E, Aidinis V, ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol. 2010 Mar 15;339(2):451-64
1*J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9
1J:70266 Graef IA, Chen F, Chen L, Kuo A, Crabtree GR, Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell. 2001 Jun 29;105(7):863-75
1J:104114 Grier JD, Xiong S, Elizondo-Fraire AC, Parant JM, Lozano G, Tissue-Specific Differences of p53 Inhibition by Mdm2 and Mdm4. Mol Cell Biol. 2006 Jan;26(1):192-8
1J:146415 Hirose T, Karasawa M, Sugitani Y, Fujisawa M, Akimoto K, Ohno S, Noda T, PAR3 is essential for cyst-mediated epicardial development by establishing apical cortical domains. Development. 2006 Apr;133(7):1389-98
1J:192465 Huang J, Elicker J, Bowens N, Liu X, Cheng L, Cappola TP, Zhu X, Parmacek MS, Myocardin regulates BMP10 expression and is required for heart development. J Clin Invest. 2012 Oct 1;122(10):3678-91
1J:107401 Jadrich JL, O'connor MB, Coucouvanis E, The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development. 2006 Apr;133(8):1529-41
1J:118346 Kern CB, Norris RA, Thompson RP, Argraves WS, Fairey SE, Reyes L, Hoffman S, Markwald RR, Mjaatvedt CH, Versican proteolysis mediates myocardial regression during outflow tract development. Dev Dyn. 2007 Mar;236(3):671-83
1J:164800 Koike S, Keino-Masu K, Masu M, Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway. Biochem Biophys Res Commun. 2010 Sep 10;400(1):66-71
1J:64428 Kruger O, Plum A, Kim JS, Winterhager E, Maxeiner S, Hallas G, Kirchhoff S, Traub O, Lamers WH, Willecke K, Defective vascular development in connexin 45-deficient mice. Development. 2000 Oct;127(19):4179-93
1J:82571 Kruithof BP, Van Den Hoff MJ, Tesink-Taekema S, Moorman AF, Recruitment of intra- and extracardiac cells into the myocardial lineage during mouse development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):303-14
1J:68770 Larsson J, Goumans MJ, Sjostrand LJ, van Rooijen MA, Ward D, Leveen P, Xu X, ten Dijke P, Mummery CL, Karlsson S, Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice. EMBO J. 2001 Apr 2;20(7):1663-73
1J:159810 Leclair RJ, Wang Q, Benson MA, Prudovsky I, Lindner V, Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1332-8
1J:187713 Li J, Bowens N, Cheng L, Zhu X, Chen M, Hannenhalli S, Cappola TP, Parmacek MS, Myocardin-like protein 2 regulates TGFbeta signaling in embryonic stem cells and the developing vasculature. Development. 2012 Oct;139(19):3531-42
1J:84789 Li S, Wang DZ, Wang Z, Richardson JA, Olson EN, The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9366-70
1J:88215 Li Z, Takakura N, Oike Y, Imanaka T, Araki K, Suda T, Kaname T, Kondo T, Abe K, Yamamura K, Defective smooth muscle development in qkI-deficient mice. Dev Growth Differ. 2003 Oct-Dec;45(5-6):449-62
1J:152700 Mancini ML, Terzic A, Conley BA, Oxburgh LH, Nicola T, Vary CP, Endoglin plays distinct roles in vascular smooth muscle cell recruitment and regulation of arteriovenous identity during angiogenesis. Dev Dyn. 2009 Aug 24;238(10):2479-2493
1J:181007 Milgrom-Hoffman M, Harrelson Z, Ferrara N, Zelzer E, Evans SM, Tzahor E, The heart endocardium is derived from vascular endothelial progenitors. Development. 2011 Nov;138(21):4777-87
1J:182740 Moya IM, Umans L, Maas E, Pereira PN, Beets K, Francis A, Sents W, Robertson EJ, Mummery CL, Huylebroeck D, Zwijsen A, Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev Cell. 2012 Mar 13;22(3):501-14
1J:75828 Noveroske JK, Lai L, Gaussin V, Northrop JL, Nakamura H, Hirschi KK, Justice MJ, Quaking is essential for blood vessel development. Genesis. 2002 Mar;32(3):218-30
1J:155001 Oh S, Lee D, Kim T, Kim TS, Oh HJ, Hwang CY, Kong YY, Kwon KS, Lim DS, Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. Mol Cell Biol. 2009 Dec;29(23):6309-20
1J:149713 Qyang Y, Martin-Puig S, Chiravuri M, Chen S, Xu H, Bu L, Jiang X, Lin L, Granger A, Moretti A, Caron L, Wu X, Clarke J, Taketo MM, Laugwitz KL, Moon RT, Gruber P, Evans SM, Ding S, Chien KR, The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Cell Stem Cell. 2007 Aug 16;1(2):165-79
1J:77725 Regan CP, Li W, Boucher DM, Spatz S, Su MS, Kuida K, Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9248-53
1J:79050 Scheidl SJ, Nilsson S, Kalen M, Hellstrom M, Takemoto M, Hakansson J, Lindahl P, mRNA expression profiling of laser microbeam microdissected cells from slender embryonic structures. Am J Pathol. 2002 Mar;160(3):801-13
1J:138768 Screen M, Dean W, Cross JC, Hemberger M, Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling. Development. 2008 Oct;135(19):3311-20
1J:144155 Shin D, Anderson DJ, Isolation of arterial-specific genes by subtractive hybridization reveals molecular heterogeneity among arterial endothelial cells. Dev Dyn. 2005 Aug;233(4):1589-604
1J:186473 Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y, Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12064-9
1J:132583 Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP, Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell. 2008 Feb;14(2):298-311
1J:36656 Takahashi Y, Imanaka T, Takano T, Spatial and temporal pattern of smooth muscle cell differentiation during development of the vascular system in the mouse embryo. Anat Embryol (Berl). 1996 Nov;194(5):515-26
1J:64981 Tanaka M, Komuro I, Inagaki H, Jenkins NA, Copeland NG, Izumo S, Nkx3.1, a murine homolog of drosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands. Dev Dyn. 2000 Oct;219(2):248-60
1J:116891 Tanaka M, Okudaira S, Kishi Y, Ohkawa R, Iseki S, Ota M, Noji S, Yatomi Y, Aoki J, Arai H, Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem. 2006 Sep 1;281(35):25822-30
1J:196073 Tasaki T, Kim ST, Zakrzewska A, Lee BE, Kang MJ, Yoo YD, Cha-Molstad HJ, Hwang J, Soung NK, Sung KS, Kim SH, Nguyen MD, Sun M, Yi EC, Kim BY, Kwon YT, UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3800-5
1J:138721 Trindade A, Ram Kumar S, Scehnet JS, Lopes-da-Costa L, Becker J, Jiang W, Liu R, Gill PS, Duarte A, Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos. Blood. 2008 Sep 1;112(5):1720-9
1J:65521 Urness LD, Sorensen LK, Li DY, Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000 Nov;26(3):328-31
1J:121420 Vieira JM, Schwarz Q, Ruhrberg C, Selective requirements for NRP1 ligands during neurovascular patterning. Development. 2007 May;134(10):1833-43
1J:76173 Vitelli F, Morishima M, Taddei I, Lindsay EA, Baldini A, Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum Mol Genet. 2002 Apr 15;11(8):915-22
1J:65678 Waller BR 3rd, McQuinn T, Phelps AL, Markwald RR, Lo CW, Thompson RP, Wessels A, Conotruncal anomalies in the trisomy 16 mouse: An immunohistochemical analysis with emphasis on the involvement of the neural crest. Anat Rec. 2000 Nov 1;260(3):279-93
1J:141490 Welser JV, Lange ND, Flintoff-Dye N, Burkin HR, Burkin DJ, Placental defects in alpha7 integrin null mice. Placenta. 2007 Nov-Dec;28(11-12):1219-28
1J:159214 Wong YH, Lu AC, Wang YC, Cheng HC, Chang C, Chen PH, Yu JY, Fann MJ, Protogenin defines a transition stage during embryonic neurogenesis and prevents precocious neuronal differentiation. J Neurosci. 2010 Mar 24;30(12):4428-39
1J:195957 Xiao Q, Pepe AE, Wang G, Luo Z, Zhang L, Zeng L, Zhang Z, Hu Y, Ye S, Xu Q, Nrf3-Pla2g7 interaction plays an essential role in smooth muscle differentiation from stem cells. Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):730-44
1J:166083 Yang G, Han Y, Tian X, Tao J, Sun M, Kang J, Yan C, Pattern of expression of the CREG gene and CREG protein in the mouse embryo. Mol Biol Rep. 2011;38(3):2133-40
1*J:60748 Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhuang Y, Su B, Mekk3 is essential for early embryonic cardiovascular development. Nat Genet. 2000 Mar;24(3):309-13
1J:98247 You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, Tsai SY, Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature. 2005 May 5;435(7038):98-104

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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory